Author details

Full Name

Hiroaki Kitano

Affiliation

ORCID

Career Start Year

1998

Papers

134

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37322439	eSPRESSO: topological clustering of single-cell transcriptomics data to reveal informative genes for spatio-temporal architectures of cells.		2023
37552896	The Evolution, Assembly, and Dynamics of Marine Holobionts.		2023
37474783	Nicotinamide mononucleotide (NMN) alleviates the poly(I:C)-induced inflammatory response in human primary cell cultures.	Sci Rep	2023
37081096	Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity.		2023
35194106	The role of the endolithic alga Ostreobium spp. during coral bleaching recovery.	Scientific Reports	2022
35437721	Toxicity Analysis of Pentachlorophenol Data with a Bioinformatics Tool Set.	Methods in Molecular Biology	2022
35671575	Social impact and governance of AI and neurotechnologies.	Neural Networks	2022
34939300	COVID-19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.	Mol Syst Biol	2021
33686086	Publisher Correction: LimeMap: a comprehensive map of lipid mediator metabolic pathways.	npj Systems Biology and Applications	2021
33941241	Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer's disease.	Alzheimer's Research and Therapy	2021
34145287	Nobel Turing Challenge: creating the engine for scientific discovery.	npj Systems Biology and Applications	2021
33608574	Effects of maoto (ma-huang-tang) on host lipid mediator and transcriptome signature in influenza virus infection.	Scientific Reports	2021
33504811	LimeMap: a comprehensive map of lipid mediator metabolic pathways.	npj Systems Biology and Applications	2021
34664389	COVID19 Disease Map, a computational knowledge repository of virus-host interaction mechanisms.	Mol Syst Biol	2021
34593802	Elucidating gene expression adaptation of phylogenetically divergent coral holobionts under heat stress.	Nature Communications	2021
32845085	SBML Level 3: an extensible format for the exchange and reuse of biological models.	Mol Syst Biol	2020
32371892	COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms.	Sci Data	2020
32628677	A Geometric Clustering Tool (AGCT) to robustly unravel the inner cluster structures of time-series gene expressions.	PLoS ONE	2020
32678106	Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms.	Sci Data	2020
30811474	Lenvatinib plus anti-PD-1 antibody combination treatment activates CD8+ T cells through reduction of tumor-associated macrophage and activation of the interferon pathway.	PLoS ONE	2019
31798962	Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds.	npj Systems Biology and Applications	2019
31863054	A prospective compound screening contest identified broader inhibitors for Sirtuin 1.	Sci Rep	2019
30868372	Integrative and theoretical research on the architecture of a biological system and its disorder.	Journal of Physiological Sciences	2019
30563907	Network-Guided Discovery of Influenza Virus Replication Host Factors.	mBio	2018
30261835	Sequence homology in eukaryotes (SHOE): interactive visual tool for promoter analysis.	BMC Genomics	2018
29075514	Deconstructing the traditional Japanese medicine "Kampo": compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms.	npj Systems Biology and Applications	2017
28355572	Precise Temporal Profiling of Signaling Complexes in Primary Cells Using SWATH Mass Spectrometry.	Cell Rep	2017
29158586	Insights into gene expression profiles induced by Socs3 depletion in keratinocytes.	Scientific Reports	2017
27866895	Empty Niches after Extinctions Increase Population Sizes of Modern Corals.	Current Biology	2016
28725465	Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways.	npj Systems Biology and Applications	2016
27131787	Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data.	Nucleic Acids Research	2016
27131384	systemsDock: a web server for network pharmacology-based prediction and analysis.	Nucleic Acids Res	2016
26860652	Multilevel modeling of physiological systems on PhysioDesigner.	Folia Pharmacologica Japonica	2016
26821131	Digital health revolution: perfect storm or perfect opportunity for pharmaceutical R&D?	Drug Discovery Today	2016
28155657	A machine learning approach for the identification of key markers involved in brain development from single-cell transcriptomic data.	BMC Genomics	2016
26673252	CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts.	PLoS One	2015
28725460	Accelerating systems biology research and its real world deployment.	npj Systems Biology and Applications	2015
28725458	Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology.	npj Systems Biology and Applications	2015
25929466	VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.	BMC Bioinformatics	2015
25585963	Oscillation of cAMP and Ca(2+) in cardiac myocytes: a systems biology approach.	Journal of Physiological Sciences	2015
25807527	Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies.	Nat Commun	2015
26523530	Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research.	Environ Health Perspect	2015
26441671	Databases for multilevel biophysiology research available at Physiome.jp.	Frontiers in Physiology	2015
26607293	Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target.	Sci Rep	2015
26046528	An Ultrasensitive Mechanism Regulates Influenza Virus-Induced Inflammation.	PLoS Pathog	2015
26388775	Identifying problematic drugs based on the characteristics of their targets.	Front Pharmacol	2015
24687050	Integrative knowledge management to enhance pharmaceutical R&D.	Nat Rev Drug Discov	2014
25464832	Influenza virus-host interactome screen as a platform for antiviral drug development.	Cell Host Microbe	2014
23832570	Integrating pathways of Parkinson's disease in a molecular interaction map.	Mol Neurobiol	2014
24899188	Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses.	J Virol	2014