Author details

Full Name

Samuel G Mackintosh

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37378433	CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.		2023
37938770	TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.	Nature	2023
37898615	Antiviral responses in a Jamaican fruit bat intestinal organoid model of SARS-CoV-2 infection.		2023
37782107	Characterization of methionine dependence in melanoma cells.		2023
37685904	Exosomal MicroRNA and Protein Profiles of Hepatitis B Virus-Related Hepatocellular Carcinoma Cells.		2023
37458933	Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels.		2023
37066392	Characterization of methionine dependence in melanoma cells.		2023
36750097	Piperlongumine conjugates induce targeted protein degradation.		2023
35172013	Proteomics Indicates Lactate Dehydrogenase Is Prognostic in Acetaminophen-Induced Acute Liver Failure Patients and Reveals Altered Signaling Pathways.	Toxicological Sciences	2022
35525905	Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic.	Oncogene	2022
36178855	Subchronic Electronic Cigarette Exposures Have Overlapping Protein Biomarkers with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.	American Journal of Respiratory Cell and Molecular Biology	2022
35758636	Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton.	eLife	2022
36561186	Antiviral response mechanisms in a Jamaican Fruit Bat intestinal organoid model of SARS-CoV-2 infection.		2022
34469831	A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells.	Cell Chem Biol	2022
34604676	Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle.	ACS Omega	2021
34072766	RuvB-Like Protein 2 Interacts with the NS1 Protein of Influenza A Virus and Affects Apoptosis That Is Counterbalanced by Type I Interferons.	Viruses	2021
33849067	Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer.	Nucleic Acids Res	2021
34163069	Phase separation drives aberrant chromatin looping and cancer development.	Nature	2021
33894670	PHF19 inhibition as a therapeutic target in multiple myeloma.	Current Research in Translational Medicine	2021
33823544	A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing.	Nucleic Acids Research	2021
33594072	ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.	Nat Commun	2021
33146391	Early Gestational Exposure to Inhaled Ozone Impairs Maternal Uterine Artery and Cardiac Function.	Toxicological Sciences	2021
34562454	DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells.	Journal of Biological Chemistry	2021
34835974	Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model.	Nutrients	2021
33004350	Epigenetic Control of Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion.	Cancer Research	2020
32027144	Accurate and Sensitive Quantitation of the Dynamic Heat Shock Proteome Using Tandem Mass Tags.	Journal of Proteome Research	2020
32022592	Respiratory defects in the <i>Crtap</i>KO mouse model of osteogenesis imperfecta.	Am J Physiol Lung Cell Mol Physiol	2020
32071147	Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome.	Molecular and Cellular Proteomics	2020
31722523	Exploiting Correlations between Protein Abundance and the Functional Status of and To Identify Virulence Factors of Potential Importance in the Pathogenesis of Osteomyelitis.	ACS Infectious Diseases	2020
32347222	ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data.	Molecular Omics	2020
31651977	Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations.	Toxicological Sciences	2020
33315917	Registered report protocol: Quantitative analysis of septin Cdc10-associated proteome in Cryptococcus neoformans.	PLoS ONE	2020
33038060	Resistant starch slows the progression of CKD in the 5/6 nephrectomy mouse model.	Physiological Reports	2020
31152063	Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation.	Journal of Biological Chemistry	2019
30699108	Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats.	PLoS ONE	2019
30739529	Proteomic characterization of the arsenic response locus in S. cerevisiae.	Epigenetics	2019
30855040	DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA.	Chemical Communications	2019
31068440	Metabolic reprogramming toward oxidative phosphorylation identifies a therapeutic target for mantle cell lymphoma.	Sci Transl Med	2019
30674537	Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma.	Cancer Research	2019
31383640	PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation.	Blood	2019
30889866	Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus.	Brain Sciences	2019
29766639	Oxidation resistance 1 is a novel senolytic target.	Aging Cell	2018
30209945	Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome.	Journal of Proteome Research	2018
30245818	A novel prostate cancer immunotherapy using prostate-specific antigen peptides and skin test reagent as an adjuvant.	SAGE Open Medicine	2018
28082109	1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.	Toxicology	2017
28350824	Time- and radiation-dose dependent changes in the plasma proteome after total body irradiation of non-human primates: Implications for biomarker selection.	PLoS ONE	2017
28400597	Indicators of responsiveness to immune checkpoint inhibitors.	Scientific Reports	2017
29225558	Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1.	Clinical Proteomics	2017
27777970	PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.	JCI insight	2016
27027282	DNA methylation on N(6)-adenine in mammalian embryonic stem cells.	Nature	2016