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Author Details

Nir Friedman
Weizmann Institute of Science
2000
57
33
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36661220Quantifying changes in the T cell receptor repertoire during thymic development.Elife2023
37325645Viral infection reveals hidden sharing of TCR CDR3 sequences between individuals.Front Immunol2023
37217651The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.Nat Cancer2023
37184893Correction of T-Cell Repertoire and Autoimmune Diabetes in NOD Mice by Non-myeloablative T-Cell Depleted Allogeneic HSCT.Stem Cells Transl Med2023
36937426Modulating the proliferative and cytotoxic properties of patient-derived TIL by a synthetic immune niche of immobilized CCL21 and ICAM1.Front Oncol2023
35967295A hierarchy of selection pressures determines the organization of the T cell receptor repertoire.Front Immunol2022
36624839From pseudo to real-time dynamics of T cell thymic differentiation.iScience2022
34651586Combined presentation and immunogenicity analysis reveals a recurrent RAS.Q61K neoantigen in melanoma.J Clin Invest2021
33835499Avidity optimization of a MAGE-A1-specific TCR with somatic hypermutation.Eur J Immunol2021
34642250Dynamic changes in tRNA modifications and abundance during T cell activation.Proc Natl Acad Sci U S A2021
32433950Endocrine Autoimmune Disease as a Fragility of Immune Surveillance against Hypersecreting Mutants.Immunity2020
30833553Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire.Nat Commun2019
31408441Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses.J Clin Invest2019
31457092Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes.Sci Adv2019
30399156Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition.PLoS One2018
29942308Expansion and Antitumor Cytotoxicity of T-Cells Are Augmented by Substrate-Bound CCL21 and Intercellular Adhesion Molecule 1.Front Immunol2018
30209080Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.Cancer Discov2018
29903938Induction of CD4 T cell memory by local cellular collectivity.Science2018
28073756Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires.Bioinformatics2017
28481982McPAS-TCR: a manually curated catalogue of pathology-associated T cell receptor sequences.Bioinformatics2017
28330904Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation.J Exp Med2017
28450864Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization.Front Immunol2017
29296744Substrate-bound CCL21 and ICAM1 combined with soluble IL-6 collectively augment the expansion of antigen-specific murine CD4<sup>+</sup> T cells.Blood Adv2017
28731407T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences.Elife2017
28716917Diverse continuum of CD4<sup>+</sup> T-cell states is determined by hierarchical additive integration of cytokine signals.Proc Natl Acad Sci U S A2017
26793190Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy.Front Immunol2016
26606974Clonal expansion under the microscope: studying lymphocyte activation and differentiation using live-cell imaging.Immunol Cell Biol2016
27136076Wishbone identifies bifurcating developmental trajectories from single-cell data.Nat Biotechnol2016
26384546Perforin-Positive Dendritic Cells Exhibit an Immuno-regulatory Role in Metabolic Syndrome and Autoimmunity.Immunity2015
26572103Universal Quake Statistics: From Compressed Nanocrystals to Earthquakes.Sci Rep2015
24421210Do all creatures possess an acquired immune system of some sort?Bioessays2014
25043040Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells.Nature2014
25024161T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity.Genome Res2014
25095879Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.Bioinformatics2014
25171404Paradoxical signaling by a secreted molecule leads to homeostasis of cell levels.Cell2014
24951031Engineering of synthetic cellular microenvironments: implications for immunity.J Autoimmun2014
23334501Dynamic single-cell measurements of gene expression in primary lymphocytes: challenges, tools and prospects.Brief Funct Genomics2013
24312094CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.Front Immunol2013
24244020Coupled IL-2-dependent extracellular feedbacks govern two distinct consecutive phases of CD4 T cell activation.J Immunol2013
23935451Mapping differentiation under mixed culture conditions reveals a tunable continuum of T cell fates.PLoS Biol2013
23219532Dynamic response diversity of NFAT isoforms in individual living cells.Mol Cell2013
23335631CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging.Proc Natl Acad Sci U S A2013
22562798Design principles of cell circuits with paradoxical components.Proc Natl Acad Sci U S A2012
23003192Universal critical dynamics in high resolution neuronal avalanche data.Phys Rev Lett2012
23002851Statistics of dislocation slip avalanches in nanosized single crystals show tuned critical behavior predicted by a simple mean field model.Phys Rev Lett2012
22984176Chromatin conformation governs T-cell receptor Jβ gene segment usage.Proc Natl Acad Sci U S A2012
23072772Monitoring the dynamics of primary T cell activation and differentiation using long term live cell imaging in microwell arrays.Lab Chip2012
22925037Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.BMC Syst Biol2012
20554028Glatiramer acetate reduces Th-17 inflammation and induces regulatory T-cells in the CNS of mice with relapsing-remitting or chronic EAE.J Neuroimmunol2010
15728384Quantitative kinetic analysis of the bacteriophage lambda genetic network.Proc Natl Acad Sci U S A2005
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Collaborators

Eric Shifrut
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 14
Asaf Madi
Co-authored papers 5
Benjamin Geiger
Co-authored papers 4
Yardena Samuels
Weizmann Institute of Science
Co-authored papers 3
Steven A Rosenberg
University of Colorado School of Medicine
Co-authored papers 2
Dana Pe'er
Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Fran??ois Van Laethem
National Cancer Institute, National Institutes of Health
Co-authored papers 2
Arie Admon
Co-authored papers 2
Richard A Scolyer
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Itay Tirosh
Weizmann Institute of Medical Sciences
Co-authored papers 1
Xingzhi Song
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Noah Stern
Weizmann Institute of Science
Co-authored papers 1
Ido Amit
Weizmann Institute of Science
Co-authored papers 1
Jennifer A Wargo
Co-authored papers 1
Amos Tanay
Weizmann Institute of Science
Co-authored papers 1
Eytan Ruppin
National Cancer Institute
Co-authored papers 1
Nuria Lopez-Bigas
Universitat Pompeu Fabra
Co-authored papers 1
Michael B Winter
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Pedro Paz
Bayer HealthCare Pharmaceuticals
Co-authored papers 1
Stefan Frantz
Co-authored papers 1
Charles S Craik
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Fred Aswad
Bayer US LLC
Co-authored papers 1
Mitchell P Levesque
University Hospital Zurich
Co-authored papers 1
Eran Elinav
German Cancer Research Center
Co-authored papers 1
Jaime Prilusky
Weizmann Institute of Science
Co-authored papers 1
Dina Schneidman-Duhovny
The Hebrew University of Jerusalem
Co-authored papers 1
Natalia Khuri
Stanford University
Co-authored papers 1
David J Adams
Wellcome Sanger Institute
Co-authored papers 1
Guang Qiang Dong
University of California san francisco
Co-authored papers 1
Release 1.2