Author details

Full Name

Adam Butler

Affiliation

Wellcome Sanger Institute

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34791067	Variant Library Annotation Tool (VaLiAnT): an oligonucleotide library design and annotation tool for saturation genome editing and other deep mutational scanning experiments.	Bioinformatics	2022
35659150	Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study.	Eur Urol	2022
35941135	Unified classification and risk-stratification in Acute Myeloid Leukemia.	Nat Commun	2022
33054126	<i>CDKN2A</i> deletion is a frequent event associated with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS).	Haematologica	2021
34824211	Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture.	Nat Commun	2021
34646017	Convergent somatic mutations in metabolism genes in chronic liver disease.	Nature	2021
31649132	RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-sequencing.	Haematologica	2020
30849372	Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis.	Cell	2019
30988298	Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.	Nat Commun	2019
31097696	Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening.	Nat Commun	2019
30829413	Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma.	Am J Hematol	2019
29656891	Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.	Cell	2018
30103702	Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting.	BMC Genomics	2018
30304655	Classification and Personalized Prognosis in Myeloproliferative Neoplasms.	N Engl J Med	2018
29662167	Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.	Nat Genet	2018
29789651	Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.	Leukemia	2018
28643781	Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.	Nat Commun	2017
29026114	The driver landscape of sporadic chordoma.	Nat Commun	2017
28945760	Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.	PLoS Genet	2017
27276561	Genomic Classification and Prognosis in Acute Myeloid Leukemia.	N Engl J Med	2016
27615322	Mutational signatures of ionizing radiation in second malignancies.	Nat Commun	2016
27930809	ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data.	Curr Protoc Bioinformatics	2016
27930805	cgpCaVEManWrapper: Simple Execution of CaVEMan in Order to Detect Somatic Single Nucleotide Variants in NGS Data.	Curr Protoc Bioinformatics	2016
27666519	Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.	Nat Commun	2016
27136393	The topography of mutational processes in breast cancer genomes.	Nat Commun	2016
27135926	Landscape of somatic mutations in 560 breast cancer whole-genome sequences.	Nature	2016
25730763	Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.	Nat Genet	2015
26647970	A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.	Nat Commun	2015
26678382	cgpPindel: Identifying Somatically Acquired Insertion and Deletion Events from Paired End Sequencing.	Curr Protoc Bioinformatics	2015
26678383	VAGrENT: Variation Annotation Generator.	Curr Protoc Bioinformatics	2015
26099045	Subclonal diversification of primary breast cancer revealed by multiregion sequencing.	Nat Med	2015
26018901	Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.	Nat Genet	2015
24413735	RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.	Nat Genet	2014
25260652	Polygenic in vivo validation of cancer mutations using transposons.	Genome Biol	2014
25271376	Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.	Elife	2014
25082706	Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.	Science	2014
24714652	Processed pseudogenes acquired somatically during cancer development.	Nat Commun	2014
24633157	Recurrent PTPRB and PLCG1 mutations in angiosarcoma.	Nat Genet	2014
24728294	Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer.	Nat Genet	2014
24429703	Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.	Nat Commun	2014
23770606	Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.	Nat Genet	2013
24325359	Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.	N Engl J Med	2013
24162739	Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone.	Nat Genet	2013
24148783	The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.	Genome Biol	2013
23900255	Computational approaches to identify functional genetic variants in cancer genomes.	Nat Methods	2013
24030381	Clinical and biological implications of driver mutations in myelodysplastic syndromes.	Blood	2013
23630320	Single-cell paired-end genome sequencing reveals structural variation per cell cycle.	Nucleic Acids Res	2013
23778141	Whole exome sequencing of adenoid cystic carcinoma.	J Clin Invest	2013
22397650	Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.	N Engl J Med	2012
22722201	The landscape of cancer genes and mutational processes in breast cancer.	Nature	2012

1 - 50 of 90

Ander Diaz-Navarro

Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo

Career Start Year 2018

Number of shared co-authors 12

Richard de Borja

The Hospital for Sick Children

Career Start Year 2012

Number of shared co-authors 41

Benjamin Raeder

Career Start Year 2012

Number of shared co-authors 26

Gordon Saksena

Broad Institute of Massachusetts Institute of Technology and Harvard

Career Start Year 2011

Number of shared co-authors 38

Emilie Lalonde

University of Pennsylvania

Career Start Year 2010

Number of shared co-authors 19

Joshua F McMichael

Washington University

Career Start Year 2009

Number of shared co-authors 12

Lixing Yang

University of Chicago, USA University of Chicago Comprehensive Cancer Center

Career Start Year 2008

Number of shared co-authors 17

Ken Chen

University of Texas MD Anderson Cancer Center

Career Start Year 2007

Number of shared co-authors 20

Kilannin Krysiak

Washington University School of Medicine

Career Start Year 2007

Number of shared co-authors 3

Paz Polak

McGill University

Career Start Year 2006

Number of shared co-authors 10

Robert C Onofrio

The Broad Institute of Harvard and MIT

Career Start Year 2005

Number of shared co-authors 36

Jamie K Teer

H. Lee Moffitt Cancer Center and Research Institute

Career Start Year 2005

Number of shared co-authors 14

Chip Stewart

Broad Institute of MIT and Harvard

Career Start Year 2004

Number of shared co-authors 41

Jianmin Wang

Roswell Park Comprehensive Cancer Center

Career Start Year 2003

Number of shared co-authors 1

Olivier Harismendy

University of California

Career Start Year 2003

Number of shared co-authors 8

Trevor J Pugh

Princess Margaret Cancer Centre, University Health Network

Career Start Year 2003

Number of shared co-authors 44

David E Larson

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 2003

Number of shared co-authors 8

Michael D McLellan

McDonnell Genome Institute, Washington University in St. Louis

Career Start Year 2003

Number of shared co-authors 23

Obi L Griffith

Washington University

Career Start Year 2003

Number of shared co-authors 19

James M Eldred

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 2003

Number of shared co-authors 9

Vladimir Makarov

Center for Immunotherapy and Precision-Immuno-Oncology, Cleveland Clinic

Career Start Year 2001

Number of shared co-authors 7

Gad Getz

Broad Institute of the Massachusetts Institute of Technology and Harvard

Career Start Year 2000

Number of shared co-authors 65

Michael N Edmonson

St. Jude Children's Research Hospital

Career Start Year 1999

Number of shared co-authors 5

Carrie Sougnez

The Broad Institute of Harvard and MIT

Career Start Year 1998

Number of shared co-authors 57

Barbara A Weir

Janssen Research and Development LLC

Career Start Year 1997

Number of shared co-authors 17

Robert S Fulton

McDonnell Genome Institute, Washington University School of Medicine

Career Start Year 1994

Number of shared co-authors 55

Marco A Marra

University of British Columbia

Career Start Year 1993

Number of shared co-authors 96

Jinghui Zhang

Changhai Hospital, Second Military Medical University

Career Start Year 1992

Number of shared co-authors 49

Elaine R Mardis

The Ohio State University

Career Start Year 1988

Number of shared co-authors 71

Matthew Meyerson

Broad Institute

Career Start Year 1983

Number of shared co-authors 62

row(s) 1 - 30 of 30

Jon Teague

Wellcome Sanger Institute

Co-authored papers 57

Phillip A Futreal

The University of Texas MD Anderson Cancer Center

Co-authored papers 56

Peter J Campbell

Wellcome Sanger Institute

Co-authored papers 53

Michael R Stratton

Wellcome Sanger Institute

Co-authored papers 53

Keiran Raine

Wellcome Sanger Institute

Co-authored papers 47

Andrew Menzies

Wellcome Sanger Institute

Co-authored papers 44

David Jones

Wellcome Sanger Institute

Co-authored papers 40

Patrick S Tarpey

Wellcome Trust Sanger Institute

Co-authored papers 35

Sarah O'Meara

Clinical Research Facility, Mercy University Hospital

Co-authored papers 34

Serena Nik-Zainal

Early Cancer Institute, University of Cambridge

Co-authored papers 30

David C Wedge

Manchester Cancer Research Centre, University of Manchester

Co-authored papers 28

Jonathan Hinton

Inivata Ltd

Co-authored papers 27

Laura Mudie

Wellcome Trust Sanger Institute

Co-authored papers 26

Chris Greenman

University of East Anglia

Co-authored papers 26

Peter Van Loo

The Francis Crick Institute

Co-authored papers 25

Sarah Edkins

Co-authored papers 23

Stuart McLaren

Wellcome Trust Sanger Institute

Co-authored papers 23

Rebecca Shepherd

Murdoch Children's Research Institute, Royal Children's Hospital

Co-authored papers 22

Ludmil B Alexandrov

Moores Cancer Center, university of california san diego

Co-authored papers 18

Sara Widaa

Co-authored papers 18

Lucy A Stebbings

Wellcome Trust Sanger Institute

Co-authored papers 17

Gemma Buck

Co-authored papers 16

Inigo Martincorena

Wellcome Sanger Institute

Co-authored papers 16

Manasa Ramakrishna

Co-authored papers 15

Gunes Gundem

Memorial Sloan Kettering Cancer Center

Co-authored papers 15

Ultan McDermott

Wellcome Sanger Institute

Co-authored papers 14

Susanna L Cooke

Institute of Cancer Sciences, University of Glasgow

Co-authored papers 14

Claire Hardy

Wellcome Sanger Institute

Co-authored papers 13

Adrienne M Flanagan

University College London, UCL Cancer Institute

Co-authored papers 13

Mark Maddison

Wellcome Sanger Institute

Co-authored papers 12

1 - 30

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