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Author Details

Val??rie de Cr??cy-Lagard
University of Florida
1990
180
51
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37205517Beyond Blast: Enabling Microbiologists to Better Extract Literature, Taxonomic Distributions and Gene Neighborhood Information for Protein Families.bioRxiv2024
369281767-Deazaguanines in DNA: functional and structural elucidation of a DNA modification system.Nucleic Acids Res2023
37916403Integrative Approach to Probe Alternative Redox Mechanisms in RNA Modifications.Acc Chem Res2023
37572349Four additional natural 7-deazaguanine derivatives in phages and how to make them.Nucleic Acids Res2023
370401654'-Deoxypyridoxine disrupts vitamin B<sub>6</sub> homeostasis in <i>Escherichia coli</i> K12 through combined inhibition of cumulative B<sub>6</sub> uptake and PLP-dependent enzyme activity.Microbiology (Reading)2023
36610787Structural basis of Qng1-mediated salvage of the micronutrient queuine from queuosine-5'-monophosphate as the biological substrate.Nucleic Acids Res2023
36729913Pyridoxal 5'-phosphate synthesis and salvage in Bacteria and Archaea: predicting pathway variant distributions and holes.Microb Genom2023
36218140Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.Protein Sci2022
35737906Dihydrouridine in the Transcriptome: New Life for This Ancient RNA Chemical Modification.ACS Chem Biol2022
35862786Metabolite Damage and Damage Control in a Minimal Genome.mBio2022
36551188Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family.Biomolecules2022
36066904The absence of the queuosine tRNA modification leads to pleiotropic phenotypes revealing perturbations of metal and oxidative stress homeostasis in Escherichia coli K12.Metallomics2022
35961013A roadmap for the functional annotation of protein families: a community perspective.Database (Oxford)2022
32963345A network approach to elucidate and prioritize microbial dark matter in microbial communities.ISME J2021
33685366Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes.RNA Biol2021
33787481Knowns and Unknowns of Vitamin B<sub>6</sub> Metabolism in <i>Escherichia coli</i>.EcoSal Plus2021
33859402Quantitative mapping of the cellular small RNA landscape with AQRNA-seq.Nat Biotechnol2021
34910575Hypermodified DNA in Viruses of E. coli and Salmonella.EcoSal Plus2021
34572495Comparative Genomic Analysis of the DUF34 Protein Family Suggests Role as a Metal Ion Chaperone or Insertase.Biomolecules2021
34652139Epoxyqueuosine Reductase QueH in the Biosynthetic Pathway to tRNA Queuosine Is a Unique Metalloenzyme.Biochemistry2021
34298953<i>Pantoea</i> Bacteriophage vB_PagS_MED16-A Siphovirus Containing a 2'-Deoxy-7-amido-7-deazaguanosine-Modified DNA.Int J Mol Sci2021
32718697Functions of Bacterial tRNA Modifications: From Ubiquity to Diversity.Trends Microbiol2021
32290235Reductive Evolution and Diversification of C5-Uracil Methylation in the Nucleic Acids of Mollicutes.Biomolecules2020
32085421Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast.Biomolecules2020
32041795Archaeosine Modification of Archaeal tRNA: Role in Structural Stabilization.J Bacteriol2020
31679841Bacterial RNA Degradosomes: Molecular Machines under Tight Control.Trends Biochem Sci2020
32776704An Enzyme Containing the Conserved Domain of Unknown Function DUF62 Acts as a Stereoselective (R<sub>s</sub> ,S<sub>c</sub> )-S-Adenosylmethionine Hydrolase.Chembiochem2020
32941607Detection of preQ0 deazaguanine modifications in bacteriophage CAjan DNA using Nanopore sequencing reveals same hypermodification at two distinct DNA motifs.Nucleic Acids Res2020
32967910An Unusual Route for <i>p</i>-Aminobenzoate Biosynthesis in Chlamydia trachomatis Involves a Probable Self-Sacrificing Diiron Oxygenase.J Bacteriol2020
32629984Survey and Validation of tRNA Modifications and Their Corresponding Genes in <i>Bacillus subtilis</i> sp Subtilis Strain 168.Biomolecules2020
32796037The DUF328 family member YaaA is a DNA-binding protein with a novel fold.J Biol Chem2020
32526159Clostridioides difficile Senses and Hijacks Host Heme for Incorporation into an Oxidative Stress Defense System.Cell Host Microbe2020
32385138Specificity in the biosynthesis of the universal tRNA nucleoside <i>N</i><sup>6</sup>-threonylcarbamoyl adenosine (t<sup>6</sup>A)-TsaD is the gatekeeper.RNA2020
32241862Whole-Genome Sequence of <i>Streptomyces kaniharaensis</i> Shomura and Niida SF-557.Microbiol Resour Announc2020
32515440Uncovering the chemistry of C-C bond formation in C-nucleoside biosynthesis: crystal structure of a C-glycoside synthase/PRPP complex.Chem Commun (Camb)2020
30511849Can Protein Expression Be Regulated by Modulation of tRNA Modification Profiles?Biochemistry2019
31730149PMP-diketopiperazine adducts form at the active site of a PLP dependent enzyme involved in formycin biosynthesis.Chem Commun (Camb)2019
317845197-Deazaguanine modifications protect phage DNA from host restriction systems.Nat Commun2019
31511377Deoxyinosine and 7-Deaza-2-Deoxyguanosine as Carriers of Genetic Information in the DNA of <i>Campylobacter</i> Viruses.J Virol2019
31481610Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.Proc Natl Acad Sci U S A2019
30745370tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii.J Bacteriol2019
30657448Essential metabolism for a minimal cell.Elife2019
28726545The t<sup>6</sup>A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans.RNA Biol2018
30159947Identification of the minimal bacterial 2'-deoxy-7-amido-7-deazaguanine synthesis machinery.Mol Microbiol2018
30010922Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.Nucleic Acids Res2018
30268903Newly-discovered enzymes that function in metabolite damage-control.Curr Opin Chem Biol2018
29382740A plastidial pantoate transporter with a potential role in pantothenate synthesis.Biochem J2018
29654173Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function.Biosci Rep2018
29106616MODOMICS: a database of RNA modification pathways. 2017 update.Nucleic Acids Res2018
29228171Gene Graphics: a genomic neighborhood data visualization web application.Bioinformatics2018
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Collaborators

Geoffrey Hutinet
University of Florida
Co-authored papers 13
Ian K Blaby
DOE Joint Genome Institute, Lawrence Berkeley National Laboratory
Co-authored papers 13
Christopher S Henry
Argonne National Laboratory
Co-authored papers 10
Crysten E Blaby-Haas
Lawrence Berkeley National Laboratory
Co-authored papers 10
Oliver Fiehn
University of California davis
Co-authored papers 8
Antoine Danchin
University of Hong Kong
Co-authored papers 6
John A Gerlt
University of Illinois at Urbana-Champaign
Co-authored papers 6
Dmitry A Rodionov
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Andrei L Osterman
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
Peter R Weigele
New England Biolabs Inc.
Co-authored papers 5
John F Hunt
Columbia University
Co-authored papers 4
Thomas J Begley
University at Albany
Co-authored papers 3
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University of California at San Diego
Co-authored papers 3
Ana Conesa
Institute for Integrative Systems Biology, Spanish National Research Council (CSIC)
Co-authored papers 3
Robert Olson
University of Chicago
Co-authored papers 2
Steven C Almo
Albert Einstein College of Medicine
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Samuel M D Seaver
Argonne National Laboratory
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Arthur S Edison
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Alex Bateman
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Rick Stevens
Argonne National Laboratory
Co-authored papers 2
Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Co-authored papers 2
Peter D Karp
Pangea Systems Inc., USA and Marine Biological Laboratory
Co-authored papers 2
Lars Hestbjerg Hansen
Co-authored papers 2
Adam M Deutschbauer
Lawrence Berkeley National Laboratory
Co-authored papers 2
Iddo Friedberg
Iowa State University
Co-authored papers 2
Alexei Savchenko
University of Toronto
Co-authored papers 2
Maria J Martin
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Stephen G Chamberlin
Southampton General Hospital
Co-authored papers 1
Stacey Cleveland
University of Florida
Co-authored papers 1
Steven E Brenner
University of California berkeley
Co-authored papers 1
Release 1.2