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Author Details

Ruben Zamora
University of Pittsburgh
1994
111
37
PMIDPaper TitleJournal TitlePublished Year
36681798MetfOrmin BenefIts Lower Extremities with Intermittent Claudication (MOBILE IC): randomized clinical trial protocol.BMC Cardiovasc Disord2023
37889540Defining spatiotemporal gene modules in liver regeneration using Analytical Dynamic Visual Spatial Omics Representation (ADViSOR).Hepatol Commun2023
38034362A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes.iScience2023
37251389Peripheral nerve repair is associated with augmented cross-tissue inflammation following vascularized composite allotransplantation.Front Immunol2023
37095162Central role for neurally dysregulated IL-17A in dynamic networks of systemic and local inflammation in combat casualties.Sci Rep2023
36710253Interleukin-17 as a spatiotemporal bridge from acute to chronic inflammation: Novel insights from computational modeling.WIREs Mech Dis2023
36039923Transcriptomic, Proteomic, and Morphologic Characterization of Healing in Volumetric Muscle Loss.Tissue Eng Part A2022
35663944Inferring Tissue-Specific, TLR4-Dependent Type 17 Immune Interactions in Experimental Trauma/Hemorrhagic Shock and Resuscitation Using Computational Modeling.Front Immunol2022
32924145Exercise Training Decreases Hepatic Injury and Metastases Through Changes in Immune Response to Liver Ischemia/Reperfusion in Mice.Hepatology2021
33519820Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver Failure.Front Immunol2021
33537029Computational Derivation of Core, Dynamic Human Blunt Trauma Inflammatory Endotypes.Front Immunol2021
33860683The Use of Multiplexing to Identify Cytokine and Chemokine Networks in the Immune-Inflammatory Response to Trauma.Antioxid Redox Signal2021
34988152Inflammatory signals and network connections implicate cell-mediated immunity in chronic venous insufficiency.Ann Transl Med2021
34017323The Effects of Tacrolimus on Tissue-Specific, Protein-Level Inflammatory Networks in Vascularized Composite Allotransplantation.Front Immunol2021
33935273Baseline Plasma Inflammatory Profile Is Associated With Response to Neoadjuvant Chemotherapy in Patients With Pancreatic Adenocarcinoma.J Immunother2021
33958628A putative "chemokine switch" that regulates systemic acute inflammation in humans.Sci Rep2021
34167455Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks.Mol Med2021
33453380Analysis of the Plasma Metabolome after Trauma, Novel Circulating Sphingolipid Signatures, and In-Hospital Outcomes.J Am Coll Surg2021
33239421IRF3 Signaling within the Mouse Stroma Influences Sepsis Pathogenesis.J Immunol2021
33093290Early dynamic orchestration of immunologic mediators identifies multiply injured patients who are tolerant or sensitive to hemorrhage.J Trauma Acute Care Surg2021
31318836An Aging-Related Single-Nucleotide Polymorphism is Associated With Altered Clinical Outcomes and Distinct Inflammatory Profiles in Aged Blunt Trauma Patients.Shock2020
31929407Association Between Inflammatory Pathways and Phenotypes of Pulmonary Dysfunction Using Cluster Analysis in Persons Living With HIV and HIV-Uninfected Individuals.J Acquir Immune Defic Syndr2020
33437775Insights into the association between coagulopathy and inflammation: abnormal clot mechanics are a warning of immunologic dysregulation following major injury.Ann Transl Med2020
30504418Computational Analysis Supports IL-17A as a Central Driver of Neutrophil Extracellular Trap-Mediated Injury in Liver Ischemia Reperfusion.J Immunol2019
31781170<i>MPPED2</i> Polymorphism Is Associated With Altered Systemic Inflammation and Adverse Trauma Outcomes.Front Genet2019
31824494Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma.Front Immunol2019
31555685Decoding the secreted inflammatory response of primary human hepatocytes to hypoxic stress <i>in vitro</i>.Ann Transl Med2019
30979951HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen.Sci Rep2019
31058776Hepatic Encephalopathy in Children With Acute Liver Failure: Utility of Serum Neuromarkers.J Pediatr Gastroenterol Nutr2019
31163056Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries.PLoS One2019
28930911An Enrichment Strategy Yields Seven Novel Single Nucleotide Polymorphisms Associated With Mortality and Altered Th17 Responses Following Blunt Trauma.Shock2018
30886940Inflammation and Disease: Modelling and Modulation of the Inflammatory Response to Alleviate Critical Illness.Curr Opin Syst Biol2018
30399158A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice.PLoS Comput Biol2018
29439934Suppressed networks of inflammatory mediators characterize chronic venous insufficiency.J Vasc Surg Venous Lymphat Disord2018
29087767Current Anti-Integrin Therapy for Ocular Disease.Semin Ophthalmol2018
27900388Data-Driven Modeling for Precision Medicine in Pediatric Acute Liver Failure.Mol Med2017
28452881Differential inflammatory networks distinguish responses to bone marrow-derived versus adipose-derived mesenchymal stem cell therapies in vascularized composite allotransplantation.J Trauma Acute Care Surg2017
29234326Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice.Front Immunol2017
29312006"Thinking" vs. "Talking": Differential Autocrine Inflammatory Networks in Isolated Primary Hepatic Stellate Cells and Hepatocytes under Hypoxic Stress.Front Physiol2017
28944195Effect of phacoemulsification on intraocular pressure in patients with primary open angle glaucoma and pseudoexfoliation glaucoma.Int J Ophthalmol2017
27513538Computational Analysis Supports an Early, Type 17 Cell-Associated Divergence of Blunt Trauma Survival and Mortality.Crit Care Med2016
27847476Dynamic Profiling: Modeling the Dynamics of Inflammation and Predicting Outcomes in Traumatic Brain Injury Patients.Front Pharmacol2016
27867357Machine Perfusion of Porcine Livers with Oxygen-Carrying Solution Results in Reprogramming of Dynamic Inflammation Networks.Front Pharmacol2016
27546764Individual-specific principal component analysis of circulating inflammatory mediators predicts early organ dysfunction in trauma patients.J Crit Care2016
25342131Injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages.FASEB J2015
26560096Insights into the Role of Chemokines, Damage-Associated Molecular Patterns, and Lymphocyte-Derived Mediators from Computational Models of Trauma-Induced Inflammation.Antioxid Redox Signal2015
26372210CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer.PLoS One2015
26635801Cardiac Arrest Disrupts Caspase-1 and Patterns of Inflammatory Mediators Differently in Skin and Muscle Following Localized Tissue Injury in Rats: Insights from Data-Driven Modeling.Front Immunol2015
26064799Impact of chemically-modified tetracycline 3 on intertwined physiological, biochemical, and inflammatory networks in porcine sepsis/ARDS.Int J Burns Trauma2015
25925680Trauma in silico: Individual-specific mathematical models and virtual clinical populations.Sci Transl Med2015
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Collaborators

University of Pittsburgh
Co-authored papers 83
University of Pittsburgh
Co-authored papers 48
University of Pittsburgh
Co-authored papers 37
University of Pittsburgh
Co-authored papers 17
Medical Subspecialities Institute, Cleveland Clinic
Co-authored papers 15
University of Pittsburgh
Co-authored papers 11
Vanderbilt Children's Medical Center
Co-authored papers 9
University of Pittsburgh Medical Center
Co-authored papers 7
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
Co-authored papers 5
Pontificia Universidad Javeriana
Co-authored papers 5
University of Pittsburgh Medical Center
Co-authored papers 4
University of Pittsburgh
Co-authored papers 4
University Medical Center Groningen
Co-authored papers 4
University of Vermont
Co-authored papers 4
University of Pittsburgh Medical Center
Co-authored papers 3
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
and Clinical Translational Science, University of Pittsburgh
Co-authored papers 3
University of Pittsburgh
Co-authored papers 2
Spectral Medical Inc.
Co-authored papers 2
Co-authored papers 2
University of Pittsburgh
Co-authored papers 2
University of Tennessee
Co-authored papers 2
Co-authored papers 2
The Pennsylvania State University, University Park
Co-authored papers 2
Hunterdon Medical Center
Co-authored papers 1
Center for Critical Care Nephrology, University of Pittsburgh
Co-authored papers 1
University of Pittsburgh School of Medicine
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1