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Author Details

John R Seavitt
Baylor College of Medicine
1992
32
19
PMIDPaper TitleJournal TitlePublished Year
37301944Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity.Commun Biol2023
37486182Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance.Dis Model Mech2023
35552317Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen.Pain2022
35448538Untargeted Metabolomics of Slc13a5 Deficiency Reveal Critical Liver-Brain Axis for Lipid Homeostasis.Metabolites2022
34450031COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay.Am J Hum Genet2021
31591642Soft windowing application to improve analysis of high-throughput phenotyping data.Bioinformatics2020
33370286Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.PLoS Genet2020
32504080A global Slc7a7 knockout mouse model demonstrates characteristic phenotypes of human lysinuric protein intolerance.Hum Mol Genet2020
32542000The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities.PLoS One2020
30854487Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts.Commun Biol2019
30773277Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes.Am J Hum Genet2019
29600991Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".Nat Methods2018
30157441Rapid and Integrative Discovery of Retina Regulatory Molecules.Cell Rep2018
30100824The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation.Conserv Genet2018
29925370Comparative analysis of single-stranded DNA donors to generate conditional null mouse alleles.BMC Biol2018
28011639Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction.J Biol Chem2017
28343629Biallelic Variants in OTUD6B Cause an Intellectual Disability Syndrome Associated with Seizures and Dysmorphic Features.Am J Hum Genet2017
29026089A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Nat Commun2017
29144450Corrigendum: High-throughput discovery of novel developmental phenotypes.Nature2017
28650954Prevalence of sexual dimorphism in mammalian phenotypic traits.Nat Commun2017
28650483Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.Nat Genet2017
27250922CRIPT exonic deletion and a novel missense mutation in a female with short stature, dysmorphic features, microcephaly, and pigmentary abnormalities.Am J Med Genet A2016
27671873Three-dimensional microCT imaging of mouse development from early post-implantation to early postnatal stages.Dev Biol2016
27626380High-throughput discovery of novel developmental phenotypes.Nature2016
22751139Aiolos promotes TH17 differentiation by directly silencing Il2 expression.Nat Immunol2012
22080921Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.Nat Immunol2011
15189737The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development.Immunity2004
11799125Unconventional potentiation of gene expression by Ikaros.J Biol Chem2002
10602003CD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction.Eur J Immunol1999
10358156Regulation of integrin-mediated T cell adhesion by the transmembrane protein tyrosine phosphatase CD45.J Immunol1999
10330160Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development.Mol Cell Biol1999
1431103Molecular cloning of the murine IL-1 beta converting enzyme cDNA.J Immunol1992
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Collaborators

Anne M Dickinson
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 18
Kent C Lloyd
University of California davis
Co-authored papers 12
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 11
Ann M Flenniken
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 11
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 11
Steve D M Brown
Mary Lyon Centre Harwell Science and Innovation Campus Oxfordshire UK.
Co-authored papers 11
Lauryl M J Nutter
The Hospital for Sick Children
Co-authored papers 10
Sara Wells
Mary Lyon Centre at Medical Research Council
Co-authored papers 10
Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 10
Helen Parkinson
European Bioinformatics Institute
Co-authored papers 10
Arthur L Beaudet
Baylor College of Medicine
Co-authored papers 10
Stephen A Murray
Columbia University.
Co-authored papers 10
Ann-Marie Mallon
The Turing Institute
Co-authored papers 10
Terrence F Meehan
European Bioinformatics Institute
Co-authored papers 9
Jeremy Mason
European Molecular Biology Laboratory - European Bioinformatics Institute
Co-authored papers 9
Paul Flicek
European Bioinformatics Institute
Co-authored papers 8
Yann Herault
Institut Clinique de la Souris (ICS), Universite de Strasbourg, CNRS, INSERM
Co-authored papers 8
Robert E Braun
University of Maine
Co-authored papers 8
Monica J Justice
The Hospital for Sick Children
Co-authored papers 7
Lynette Bower
University of California davis
Co-authored papers 7
Karen L Svenson
Co-authored papers 7
Damian Smedley
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 7
Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
Co-authored papers 6
Xiang Gao
Nanjing Biomedical Research Institute, Nanjing University
Co-authored papers 6
Mark Moore
Co-authored papers 6
Glauco P Tocchini-Valentini
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 6
Juan Gallegos
Baylor College of Medicine
Co-authored papers 6
William C Skarnes
Wellcome Trust Sanger Institute
Co-authored papers 5
Valerie Gailus-Durner
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 5
David B West
Children's Hospital Oakland Research Institute
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Release 1.2