Author details

Full Name

Clive N Svendsen

Affiliation

ORCID

Career Start Year

1985

Papers

245

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37460827	Reversal of dual epigenetic repression of non-canonical Wnt-5a normalises diabetic corneal epithelial wound healing and stem cells.		2023
37762529	Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons.		2023
37743503	GMP-grade human neural progenitors delivered subretinally protect vision in rat model of retinal degeneration and survive in minipigs.		2023
37640947	Survival of the fittest glia.		2023
37786347	Human Neural Progenitors Expressing GDNF Enhance Retinal Protection in a Rodent Model of Retinal Degeneration.		2023
37084724	Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration.		2023
36764301	Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects.	Neuron	2023
35123656	Lineage tracing: The gold standard to claim direct reprogramming inÂ vivo.	Molecular Therapy	2022
35715505	Regenerative and restorative medicine for eye disease.	Nat Med	2022
35527562	The proSAAS Chaperone Provides Neuroprotection and Attenuates Transsynaptic Î±-Synuclein Spread in Rodent Models of Parkinson's Disease.	Journal of Parkinson's Disease	2022
36205191	Tissue clearing of human iPSC-derived organ-chips enables high resolution imaging and analysis.	Lab on a Chip	2022
36064599	Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial.	Nature Medicine	2022
35357974	Sodium Phenylbutyrate Rescues Thyroid Hormone Transport in Brain Endothelial-Like Cells.	Thyroid	2022
35350867	AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.	Thyroid	2022
35046530	Getting the upper hand in ALS.	Gene Therapy	2022
34783606	Emerging technologies and their impact on regulatory science.	Exp Biol Med (Maywood)	2022
35115730	Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.	Nat Neurosci	2022
34965417	Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis.	Cell Rep	2021
33956384	Oligodendrocyte progenitor cell maturation is dependent on dual function of MCT8 in the transport of thyroid hormone across brain barriers and the plasma membrane.	GLIA	2021
33784499	Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.	Cell Rep	2021
34334425	Stem Cell-Derived Dopamine Neurons: Will They Replace DBS as the Leading Neurosurgical Treatment for Parkinson's Disease?	J Parkinsons Dis	2021
33181273	Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells.	Nanomedicine: Nanotechnology, Biology, and Medicine	2021
33382996	Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures.		2021
34746703	Microglial transcription profiles in mouse and human are driven by APOE4 and sex.	iScience	2021
33396621	Modeling Intestinal Epithelial Response to Interferon-Î³ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids.	International Journal of Molecular Sciences	2020
32321511	Recent advances in human iPSC-derived models of the blood-brain barrier.	Fluids and Barriers of the CNS	2020
32142662	Multi-lineage Human iPSC-Derived Platforms for Disease Modeling and Drug Discovery.		2020
32176199	Generation of a Human iPSC-Based Blood-Brain Barrier Chip.	Journal of Visualized Experiments	2020
32054965	Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer's disease.	Communications Biology	2020
31988461	iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates.	Nat Med	2020
32093254	Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD.	International Journal of Molecular Sciences	2020
32521508	Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls.	iScience	2020
32511402	Human iPSC-Derived Cardiomyocytes are Susceptible to SARS-CoV-2 Infection.		2020
32673563	G<sub>4</sub>C<sub>2</sub> Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD.	Neuron	2020
32560741	Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.	Molecular Autism	2020
32835305	Human iPSC-Derived Cardiomyocytes Are Susceptible to SARS-CoV-2 Infection.	Cell Reports Medicine	2020
31316341	Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support.	Frontiers in Neuroscience	2019
30468382	Quantum Capacitance Based Amplified Graphene Phononics for Studying Neurodegenerative Diseases.	ACS applied materials & interfaces	2019
30515959	In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival.	Proteomics	2019
30820468	Young bone marrow transplantation preserves learning and memory in old mice.	Communications Biology	2019
31173718	Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications.	Cell Stem Cell	2019
29576540	Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development.	Stem Cell Reports	2018
29930984	Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.	Cellular and Molecular Gastroenterology and Hepatology	2018
30150108	Report of the international conference on manufacturing and testing of pluripotent stem cells.	Biologicals	2018
30080719	Stem cell transplantation for amyotrophic lateral sclerosis.	Current Opinion in Neurology	2018
29311338	Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.	Proceedings of the National Academy of Sciences of the United States of America	2018
29566793	Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.	Neuron	2018
29706501	Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells.	Stem Cell Reports	2018
29476127	Huntington modeling improves with age.	Nature Neuroscience	2018
29656478	Transplantation of Neural Progenitor Cells Expressing Glial Cell Line-Derived Neurotrophic Factor into the Motor Cortex as a Strategy to Treat Amyotrophic Lateral Sclerosis.	Stem Cells	2018