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Author Details

Laura Caberlotto
The Microsoft Research University of Trento
1997
49
25
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37174725Protein Networks Associated with Native Metabotropic Glutamate 1 Receptors (mGlu<sub>1</sub>) in the Mouse Cerebellum.Cells2023
33546175Degree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease Genes.Biology (Basel)2021
33197196Selective Inhibitors of G2019S-LRRK2 Kinase Activity.J Med Chem2020
31813757Gene expression signature of antidepressant treatment response/non-response in Flinders Sensitive Line rats subjected to maternal separation.Eur Neuropsychopharmacol2020
30850634Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases.Sci Rep2019
29529088Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy.PLoS One2018
29950584Cross-species evidence from human and rat brain transcriptome for growth factor signaling pathway dysregulation in major depression.Neuropsychopharmacology2018
27713095Nutrition for the ageing brain: Towards evidence for an optimal diet.Ageing Res Rev2017
27079753Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Alzheimers Dement2016
27612656Systems biology integration of proteomic data in rodent models of depression reveals involvement of the immune response and glutamatergic signaling.Proteomics Clin Appl2016
27585646Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer's disease.Sci Rep2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
25362968Systems biology meets -omic technologies: novel approaches to biomarker discovery and companion diagnostic development.Expert Rev Mol Diagn2015
26608884Systems biology approaches to study the molecular effects of caloric restriction and polyphenols on aging processes.Genes Nutr2015
26154857Novel drug target identification for the treatment of dementia using multi-relational association mining.Sci Rep2015
24551850Network analysis of neurodegenerative disease highlights a role of Toll-like receptor signaling.Biomed Res Int2014
24908109A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy.BMC Syst Biol2014
23793101Differential effects of glycogen synthase kinase 3 (GSK3) inhibition by lithium or selective inhibitors in the central nervous system.Naunyn Schmiedebergs Arch Pharmacol2013
24265728The central role of AMP-kinase and energy homeostasis impairment in Alzheimer's disease: a multifactor network analysis.PLoS One2013
20868698Central administration of NPY or an NPY-Y5 selective agonist increase in vivo extracellular monoamine levels in mesocorticolimbic projecting areas.Neuropharmacology2011
21055451Neuropeptide Y-Y2 receptor knockout mice: influence of genetic background on anxiety-related behaviors.Neuroscience2011
19846047Chronic psychosocial stress alters NPY system: different effects in rat and tree shrew.Prog Neuropsychopharmacol Biol Psychiatry2010
21074426The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists.Bioorg Med Chem Lett2010
20813523Discovery and structure-activity relationship of a novel spirocarbamate series of NPY Y5 antagonists.Bioorg Med Chem Lett2010
20832426Adenoviral-mediated Cre expression effectively suppresses GlyT1 binding in the thalamic area of GlyT1 conditional knock-out mice.J Neurosci Methods2010
20951033Design, synthesis and SAR of a novel series of benzimidazoles as potent NPY Y5 antagonists.Bioorg Med Chem Lett2010
20630754Synthesis and structure-activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists.Bioorg Med Chem Lett2010
19607714Evaluation of expression and function of the H+/myo-inositol transporter HMIT.BMC Cell Biol2009
19581086The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists.Bioorg Med Chem Lett2009
18077069Acute stress differentially affects corticotropin-releasing hormone mRNA expression in the central amygdala of the "depressed" flinders sensitive line and the control flinders resistant line rats.Prog Neuropsychopharmacol Biol Psychiatry2008
18973598Chronic stress-induced alterations in amygdala responsiveness and behavior--modulation by trait anxiety and corticotropin-releasing factor systems.Eur J Neurosci2008
16904299Electroconvulsive stimuli selectively affect behavior and neuropeptide Y (NPY) and NPY Y(1) receptor gene expressions in hippocampus and hypothalamus of Flinders Sensitive Line rat model of depression.Eur Neuropsychopharmacol2007
16959374Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze.Peptides2006
15845098Down-regulation of amygdala preprotachykinin A mRNA but not 3H-SP receptor binding sites in subjects affected by mood disorders and schizophrenia.Eur J Neurosci2005
12968131Corticotropin-releasing hormone (CRH) mRNA expression in rat central amygdala in cannabinoid tolerance and withdrawal: evidence for an allostatic shift?Neuropsychopharmacology2004
12752772Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain.Eur J Neurosci2003
11830177Leptin suppression of hypothalamic NPY expression and feeding, but not amygdala NPY expression and experimental anxiety.Pharmacol Biochem Behav2002
11707630Differential expression of NPY and its receptors in alcohol-preferring AA and alcohol-avoiding ANA rats.Alcohol Clin Exp Res2001
11244494Differential expression of diacylglycerol kinase iota and L18A mRNAs in the brains of alcohol-preferring AA and alcohol-avoiding ANA rats.Mol Psychiatry2001
11377922Neuropeptide Y Y(1) and Y(2) receptor mRNA expression in the prefrontal cortex of psychiatric subjects. Relationship of Y(2) subtype to suicidal behavior.Neuropsychopharmacology2001
11058155Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression.Proc Natl Acad Sci U S A2000
11207429Characterization of NPY mRNA-expressing cells in the human brain: co-localization with Y2 but not Y1 mRNA in the cerebral cortex, hippocampus, amygdala, and striatum.J Chem Neuroanat2000
10501568Reduced neuropeptide Y mRNA expression in the prefrontal cortex of subjects with bipolar disorder.Neuroreport1999
10327163Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression.Neurosci Lett1999
9729278Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment.Brain Res Mol Brain Res1998
9692720On the relationship of neuropeptide Y Y1 receptor-immunoreactive neuronal structures to the neuropeptide Y-immunoreactive nerve terminal networks. A double immunolabelling analysis in the rat brain.Neuroscience1998
9692752Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain.Neuroscience1998
9143015NPY Y1 receptor like immunoreactivity exists in a subpopulation of beta-endorphin immunoreactive nerve cells in the arcuate nucleus: a double immunolabelling analysis in the rat.Neurosci Lett1997
9215705Localization of neuropeptide Y Y1 mRNA in the human brain: abundant expression in cerebral cortex and striatum.Eur J Neurosci1997
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Collaborators

University of Trento
Co-authored papers 9
Co-authored papers 8
University of Pisa
Co-authored papers 6
Queen's University Belfast
Co-authored papers 1
Winship Cancer Institute, Emory University
Co-authored papers 1
Louisiana Tech University
Co-authored papers 1
University of Ottawa
Co-authored papers 1
Co-authored papers 1
university of california san diego Health System
Co-authored papers 1
and Barnett Institute, Northeastern University
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Armed Forces Radiobiology Research Institute
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Chang Gung Memorial Hospital-Linko, Chang Gung University
Co-authored papers 1
University of Kentucky
Co-authored papers 1
The University of Texas Southwestern Medical Center
Co-authored papers 1
Oncode Institute
Co-authored papers 1
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 1
Co-authored papers 1
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 1
The Barcelona Institute for Science and Technology
Co-authored papers 1
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 1
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Co-authored papers 1
Rush University Medical Center
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1