Skip to Main Content

Author Details

Charles Patrick Reynolds
Cancer Center, Texas Tech University Health Sciences Center
1975
287
73
PMIDPaper TitleJournal TitlePublished Year
36550020Non-synonymous, synonymous, and non-coding nucleotide variants contribute to recurrently altered biological processes during retinoblastoma progression.Genes Chromosomes Cancer2023
37199745Phase I trial of intravenous fenretinide (4-HPR) plus safingol in advanced malignancies.Cancer Chemother Pharmacol2023
35211994Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.EMBO J2022
35947641Alternative Lengthening of Telomeres in Cancer Confers a Vulnerability to Reactivation of p53 Function.Cancer Res2022
33323683The O6-methyguanine-DNA methyltransferase inhibitor O6-benzylguanine enhanced activity of temozolomide + irinotecan against models of high-risk neuroblastoma.Anticancer Drugs2021
33578855Neuroblastoma Invasion Strategies Are Regulated by the Extracellular Matrix.Cancers (Basel)2021
34408079ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156.Sci Transl Med2021
33079733Vorinostat and fenretinide synergize in preclinical models of T-cell lymphoid malignancies.Anticancer Drugs2021
33423090A phase I study of intravenous fenretinide (4-HPR) for patients with malignant solid tumors.Cancer Chemother Pharmacol2021
33332735Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.EMBO Mol Med2021
32409685MYC transcription activation mediated by OCT4 as a mechanism of resistance to 13-cisRA-mediated differentiation in neuroblastoma.Cell Death Dis2020
31637848miR-15a-5p, miR-15b-5p, and miR-16-5p inhibit tumor progression by directly targeting MYCN in neuroblastoma.Mol Oncol2020
30272587Cytotoxicity and molecular activity of fenretinide and metabolites in T-cell lymphoid malignancy, neuroblastoma, and ovarian cancer cell lines in physiological hypoxia.Anticancer Drugs2019
31780656The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status.Nat Commun2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31484706Fenretinide via NOXA Induction, Enhanced Activity of the BCL-2 Inhibitor Venetoclax in High BCL-2-Expressing Neuroblastoma Preclinical Models.Mol Cancer Ther2019
30952988Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models.Nat Biomed Eng2019
30836314Hydrophilic interaction liquid chromatography-tandem mass spectrometric approach for simultaneous determination of safingol and D-erythro-sphinganine in human plasma.J Chromatogr B Analyt Technol Biomed Life Sci2019
30563935Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.Clin Cancer Res2019
28921800Initial testing (stage 1) of M6620 (formerly VX-970), a novel ATR inhibitor, alone and combined with cisplatin and melphalan, by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2018
29967609A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931.Front Immunol2018
30046297Corrigendum: A Comprehensive Safety Trial of Chimeric Antibody 14.18 With GM-CSF, IL-2, and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: Children's Oncology Group Study ANBL0931.Front Immunol2018
30251395Cytotoxic activity of difluoromethylornithine compared with fenretinide in neuroblastoma cell lines.Pediatr Blood Cancer2018
29769286Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma.Sci Transl Med2018
29603591Phase I study of vorinostat in combination with isotretinoin in patients with refractory/recurrent neuroblastoma: A new approaches to Neuroblastoma Therapy (NANT) trial.Pediatr Blood Cancer2018
27650817Initial testing (stage 1) of the curaxin CBL0137 by the pediatric preclinical testing program.Pediatr Blood Cancer2017
28340497P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models.Int J Cancer2017
28429653Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives.Exp Biol Med (Maywood)2017
28350380Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.Sci Data2017
28420721Phase I Study of Fenretinide Delivered Intravenously in Patients with Relapsed or Refractory Hematologic Malignancies: A California Cancer Consortium Trial.Clin Cancer Res2017
28119491Reactive Oxygen Species-Mediated Synergism of Fenretinide and Romidepsin in Preclinical Models of T-cell Lymphoid Malignancies.Mol Cancer Ther2017
29206221Corrigendum: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.Sci Data2017
28636942Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres.Cell Rep2017
28656755Microfluidic Separation of Lymphoblasts for the Isolation of Acute Lymphoblastic Leukemia Using the Human Transferrin Receptor as a Capture Target.Anal Chem2017
27786412Initial testing of VS-4718, a novel inhibitor of focal adhesion kinase (FAK), against pediatric tumor models by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2017
26080839Modulation of Glucocorticoid Resistance in Pediatric T-cell Acute Lymphoblastic Leukemia by Increasing BIM Expression with the PI3K/mTOR Inhibitor BEZ235.Clin Cancer Res2016
28881577A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.Oncotarget2016
26438783Crizotinib Synergizes with Chemotherapy in Preclinical Models of Neuroblastoma.Clin Cancer Res2016
26398108Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program.Pediatr Blood Cancer2016
27747870Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer.Br J Pharmacol2016
27238606Initial Testing (Stage 1) of MK-8242-A Novel MDM2 Inhibitor-by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2016
27530131Reactive Oxygen Species Mediates the Synergistic Activity of Fenretinide Combined with the Microtubule Inhibitor ABT-751 against Multidrug-Resistant Recurrent Neuroblastoma Xenografts.Mol Cancer Ther2016
27496711Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis.Cancer Res2016
27092812A Phase I New Approaches to Neuroblastoma Therapy Study of Buthionine Sulfoximine and Melphalan With Autologous Stem Cells for Recurrent/Refractory High-Risk Neuroblastoma.Pediatr Blood Cancer2016
26797892Initial Testing of NSC 750854, a Novel Purine Analog, Against Pediatric Tumor Models by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2016
25263539Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673.Pediatr Blood Cancer2015
26154614Initial testing (stage 1) of the anti-microtubule agents cabazitaxel and docetaxel, by the pediatric preclinical testing program.Pediatr Blood Cancer2015
26153194Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma.Pediatr Blood Cancer2015
25845499Preservation of high glycolytic phenotype by establishing new acute lymphoblastic leukemia cell lines at physiologic oxygen concentration.Exp Cell Res2015
25711293Disialoganglioside-specific human natural killer cells are effective against drug-resistant neuroblastoma.Cancer Immunol Immunother2015
  • 1 - 50 of 287

Recommended Authors

University Children's Hospital of Cologne
Career Start Year 2003
Number of shared co-authors 6
Perelman School of Medicine at the University of Pennsylvania
Career Start Year 2002
Number of shared co-authors 23
Princess Margaret Cancer Centre
Career Start Year 1999
Number of shared co-authors 0
College of Human Medicine, Michigan State University
Career Start Year 1998
Number of shared co-authors 0
St. Jude Children's Research Hospital
Career Start Year 1997
Number of shared co-authors 2
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Career Start Year 1996
Number of shared co-authors 10
University Children's Hospital
Career Start Year 1994
Number of shared co-authors 4
Hopp Children's Cancer Center Heidelberg (KiTZ)
Career Start Year 1993
Number of shared co-authors 9
Oregon Health and Science University
Career Start Year 1993
Number of shared co-authors 7
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Career Start Year 1990
Number of shared co-authors 2
Ruth Rappaport Children's Hospital
Career Start Year 1988
Number of shared co-authors 0
Center for Cancer Research, National Cancer Institute
Career Start Year 1987
Number of shared co-authors 9
National Institute of Neurological Disorders and Stroke
Career Start Year 1986
Number of shared co-authors 0
Leeds Institute of Medical Research, St. James's University Hospital
Career Start Year 1986
Number of shared co-authors 6
Children's Hospital at Montefiore.
Career Start Year 1986
Number of shared co-authors 7
University of California san francisco
Career Start Year 1985
Number of shared co-authors 9
Clinical Research Division, Fred Hutchinson Cancer Center
Career Start Year 1985
Number of shared co-authors 9
University of California San Francisco
Career Start Year 1985
Number of shared co-authors 0
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Career Start Year 1984
Number of shared co-authors 6
Institut Curie
Career Start Year 1983
Number of shared co-authors 9
Baylor College of Medicine
Career Start Year 1982
Number of shared co-authors 26
Boston Children's Hospital and Harvard Medical School
Career Start Year 1982
Number of shared co-authors 16
Children's Cancer Research Institute, Medical University of Vienna
Career Start Year 1978
Number of shared co-authors 9
National Cancer Institute
Career Start Year 1978
Number of shared co-authors 2
Mayo Clinic
Career Start Year 1977
Number of shared co-authors 3
University Hospital Munster
Career Start Year 1976
Number of shared co-authors 1
Institute of Biomedical Engineering (IBME), University of Oxford
Career Start Year 1976
Number of shared co-authors 2
Princess Margaret Cancer Centre, University Health Network
Career Start Year 1975
Number of shared co-authors 0
University of Texas M.D. Anderson Cancer Center
Career Start Year 1974
Number of shared co-authors 12
Heersink School of Medicine, The University of Alabama at Birmingham
Career Start Year 1970
Number of shared co-authors 4

Collaborators

Children's Hospital of Philadelphia
Co-authored papers 83
National Cancer Institute
Co-authored papers 74
The University of Texas Health Science Center at San Antonio
Co-authored papers 70
University of Texas MD Anderson Cancer Center
Co-authored papers 62
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 61
Co-authored papers 61
Co-authored papers 59
St. Jude Children's Research Hospital.
Co-authored papers 43
The University of Texas Health Science Center at San Antonio
Co-authored papers 29
Center for Epigenetics, Van Andel Research Institute
Co-authored papers 20
Co-authored papers 11
Co-authored papers 9
Yale University School of Medicine
Co-authored papers 6
British Columbia Cancer Research Centre
Co-authored papers 5
Co-authored papers 5
Co-authored papers 4
Greehey Children's Cancer Research Institute
Co-authored papers 4
St. Jude Children's Research Hospital
Co-authored papers 4
Co-authored papers 3
School of Clinical Medicine
Co-authored papers 3
Children's Hospital of Philadelphia, USA. [2] Center for Childhood Cancer Research
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
Center for Cancer Research, National Cancer Institute
Co-authored papers 3
David Geffen School of Medicine at university of california los angeles
Co-authored papers 3
University of Texas MD Anderson Cancer Center
Co-authored papers 3
University of Pennsylvania Perelman School of Medicine
Co-authored papers 3
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 2
Co-authored papers 2
University of Chicago
Co-authored papers 2