Author details

Full Name

Xin He

Affiliation

ORCID

Career Start Year

2013

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36824788	DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network.	Res Sq	2023
37591828	Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation.		2023
35576194	Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning.	PLoS Comput Biol	2022
34489471	A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci.	Nat Commun	2021
33791774	DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways.	Brief Bioinform	2021
33647928	CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression.		2021
33268355	Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.	Sci Adv	2020
32472065	Publisher Correction: Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics.	Nat Genet	2020
32451458	Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics.	Nat Genet	2020
32601472	Genetic analyses support the contribution of mRNA N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) modification to human disease heritability.	Nat Genet	2020
32522981	mTADA is a framework for identifying risk genes from de novo mutations in multiple traits.	Nat Commun	2020
32912334	Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits.		2020
32732423	Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.	Science	2020
31363082	Detailed modeling of positive selection improves detection of cancer driver genes.	Nat Commun	2019
29875476	A comparative study of the genetic components of three subcategories of autism spectrum disorder.	Mol Psychiatry	2019
31117646	Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.	J Am Chem Soc	2019
30792016	Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice.	Molecular Metabolism	2019
29700473	An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.	Nat Genet	2018
30134165	PAK2 Haploinsufficiency Results in Synaptic Cytoskeleton Impairment and Autism-Related Behavior.	Cell Reports	2018
29754769	A Statistical Framework for Mapping Risk Genes from De Novo Mutations in Whole-Genome-Sequencing Studies.	American Journal of Human Genetics	2018
28052920	Evolution of transcript modification by <i>N</i><sup>6</sup>-methyladenosine in primates.	Genome Res	2017
28831199	Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders.	Mol Psychiatry	2017
29262854	Integrated Bayesian analysis of rare exonic variants to identify risk genes for schizophrenia and neurodevelopmental disorders.	Genome Med	2017
25849321	Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.	Mol Psychiatry	2016
25939403	Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.	Mol Psychiatry	2016
26400819	De novo ChIP-seq analysis.	Genome Biol	2015
26402605	Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.	Neuron	2015
24602502	DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics.	Mol Autism	2014
25363760	Synaptic, transcriptional and chromatin genes disrupted in autism.	Nature	2014
23643380	Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS.	Am J Hum Genet	2013
23966865	Integrated model of de novo and inherited genetic variants yields greater power to identify risk genes.	PLoS Genet	2013
24267886	Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.	Cell	2013