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Author Details

Amit Khera
2004
331
71
PMIDPaper TitleJournal TitlePublished Year
37291107South Asian medical cohorts reveal strong founder effects and high rates of homozygosity.Nat Commun2023
36314243Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting in Nonhuman Primate and Mouse Models.Circulation2023
36315649Advances and Applications of Polygenic Scores for Coronary Artery Disease.Annual Review of Medicine2023
37814896Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research.Circ Genom Precis Med2023
37567021Age-Related Differences in the Contribution of Systolic Blood Pressure and Biomarkers to Cardiovascular Disease Risk Prediction: The Atherosclerosis Risk in Communities (ARIC) Study.Am J Cardiol2023
37414900A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.Nat Med2023
37158070Impact of Family History of Premature Coronary Artery Disease on Noninvasive Testing in Stable Chest Pain.J Am Heart Assoc2023
36650173BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases.Nat Commun2023
37205493Rare penetrant mutations confer severe risk of common diseases.medRxiv2023
37014069Causal effect of adiposity on the risk of 19 gastrointestinal diseases: a Mendelian randomization study.2023
37323864Association of Acculturation and Cardiometabolic Disease Among Immigrants of South Asian Ancestry.2023
37262146Rare penetrant mutations confer severe risk of common diseases.Science2023
36563697Machine learning to assess coronary artery disease status-is it helpful?2023
37128940Popular Dietary Patterns: Alignment With American Heart Association 2021 Dietary Guidance: A Scientific Statement From the American Heart Association.Circulation2023
37068134How Low Can You Go? New Evidence Supports No Lower Bound to Low-Density Lipoprotein Cholesterol Level in Secondary Prevention.Circulation2023
37188660GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.Nat Commun2023
37377635Exploring the link between Gilbert's syndrome and atherosclerotic cardiovascular disease: insights from a subpopulation-based analysis of over one million individuals.Eur Heart J Open2023
37186683Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease.Circulation2023
36937991Genomic analysis of lean individuals with NAFLD identifies monogenic disorders in a prospective cohort study.2023
36931545Coronary artery calcium, hepatic steatosis, and atherosclerotic cardiovascular disease risk in patients with type 2 diabetes mellitus: Results from the Dallas heart study.2023
36681150The Relationship Between Coronary Artery Calcification and Carotid Intima Media Thickness and Hippocampal Volume: An Analysis From the Dallas Heart Study.2023
36723951Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease.JAMA Cardiol2023
37495702Author Correction: A single-cell atlas of human and mouse white adipose tissue.Nature2023
37492105Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins.Cell Genom2023
35157518Statin Use in Pregnancy: Is It Time For a Paradigm Shift?Circulation2022
36372681Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics.Obesity (Silver Spring)2022
36048760Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.PLoS Genet2022
35773565COVID-19 and Cardiometabolic Health: Lessons Gleaned from the Pandemic and Insights for the Next Wave.Curr Atheroscler Rep2022
35654975A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.Nat Genet2022
35836215Polygenic risk for type 2 diabetes, lifestyle, metabolic health, and cardiovascular disease: a prospective UK Biobank study.Cardiovascular Diabetology2022
36169945Measured Blood Pressure, Genetically Predicted Blood Pressure, and Cardiovascular Disease Risk in the UK Biobank.JAMA Cardiology2022
35896726Silhouette images enable estimation of body fat distribution and associated cardiometabolic risk.NPJ Digit Med2022
35835500Polygenic Score Assessed in Young Adulthood and Onset of Subclinical Atherosclerosis and Coronary Heart Disease.Journal of the American College of Cardiology2022
35583889Rare and Common Genetic Variation Underlying the Risk of Hypertrophic Cardiomyopathy in a National Biobank.JAMA Cardiol2022
35583136Estimated Yield of Screening for Heterozygous Familial Hypercholesterolemia With and Without Genetic Testing in US Adults.J Am Heart Assoc2022
35381001Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.PLoS Genetics2022
36346053Association of Number of Live Births With Electrocardiographic and Cardiac Structural Changes.Journal of the American Heart Association2022
36007985Polygenic Risk Score Predicts Sudden Death in Patients With Coronary Disease and Preserved Systolic Function.J Am Coll Cardiol2022
35568683Applying an LDL-C threshold-based approach to identify individuals with familial hypercholesterolemia.Journal of Clinical Lipidology2022
35943062Coronary Artery Calcium Score to Refine the Use of PCSK9i in Asymptomatic Individuals: A Multicohort Study.J Am Heart Assoc2022
36147540Clinical Implementation of Combined Monogenic and Polygenic Risk Disclosure for Coronary Artery Disease.JACC Adv2022
35869152Prediction performance and fairness heterogeneity in cardiovascular risk models.Sci Rep2022
35614072The potential of polygenic scores to improve cost and efficiency of clinical trials.Nat Commun2022
35361355Patients With Myocarditis Associated With COVID-19 Vaccination.Journal of the American College of Cardiology2022
36061534Associations between polygenic risk of coronary artery disease and type 2 diabetes, lifestyle, and cardiovascular mortality: A prospective UK Biobank study.Front Cardiovasc Med2022
36061365GlycA, hsCRP differentially associated with MI, ischemic stroke: In the Dallas Heart Study and Multi-Ethnic Study of Atherosclerosis: GlycA, hsCRP Differentially Associated MI, Stroke.Am J Prev Cardiol2022
35675159Association of Genome-Wide Polygenic Risk Score for Body Mass Index With Cardiometabolic Health From Childhood Through Midlife.Circulation. Genomic and precision medicine2022
35544052Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality.JAMA Cardiol2022
35785971Highlights in ASCVD Primary Prevention for 2021.Journal of the American Heart Association2022
35665268Cardiovascular Disease Risk Modeling for Astronauts: Making the Leap From Earth to Space.Frontiers in Cardiovascular Medicine2022
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Cardiovascular Research Center, Massachusetts General Hospital
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Center for Computational Health
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Broad Institute of Harvard and the Massachusetts Institute of Technology
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University of Texas Southwestern Medical Center
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University of Texas Southwestern Medical Center Dallas TX USA.
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Vanderbilt-Ingram Cancer Center, Vanderbilt University
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Broad Institute of MIT and Harvard
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Center for Health Data Science and Analytics
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Baylor College of Medicine
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Beth Israel Deaconess Medical Center
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Cardiovascular Research Center, Massachusetts General Hospital
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