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Author Details

Ariel E Feldstein
University of California San Diego
1997
218
73
PMIDPaper TitleJournal TitlePublished Year
38092312BRP39 Regulates Neutrophil Recruitment in NLRP3 Inflammasome-Induced Liver Inflammation.Cell Mol Gastroenterol Hepatol2024
36059147Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.Hepatology2023
37598239JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.Sci Rep2023
37664463Pyroptosis and gasdermins-Emerging insights and therapeutic opportunities in metabolic dysfunction-associated steatohepatitis.Front Cell Dev Biol2023
37953339Correction to: Myeloidâ¿¿specific deletion of chitinaseâ¿¿3â¿¿like 1 protein ameliorates murine dietâ¿¿induced steatohepatitis progression.J Mol Med (Berl)2023
37893181Extracellular Vesicles as Therapeutic and Diagnostic Tools for Chronic Liver Diseases.Biomedicines2023
37973811Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders.Sci Rep2023
37256266Antisense Oligonucleotide Therapy Decreases IL-1β Expression and Prolongs Survival in Mutant Nlrp3 Mice.J Immunol2023
37308266Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis.J Pharmacol Exp Ther2023
37166517Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression.J Mol Med (Berl)2023
34592216Pyroptosis in Steatohepatitis and Liver Diseases.J Mol Biol2022
35787975Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis.Cell Mol Gastroenterol Hepatol2022
36384118Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH.Cell Rep2022
35987202A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.Cell Metab2022
36263326The role of oxidized lipid species in insulin resistance and NASH in children.Front Endocrinol (Lausanne)2022
36194627NLRP3 activation in neutrophils induces lethal autoinflammation, liver inflammation, and fibrosis.EMBO Rep2022
34997987NOD-like receptor protein 3 activation causes spontaneous inflammation and fibrosis that mimics human NASH.Hepatology2022
35264978Cell-to-Cell Communications in Alcohol-Associated Liver Disease.Front Physiol2022
35297549A low n-6 to n-3 polyunsaturated fatty acid ratio diet improves hyperinsulinaemia by restoring insulin clearance in obese youth.Diabetes Obes Metab2022
35194091Protein and miRNA profile of circulating extracellular vesicles in patients with primary sclerosing cholangitis.Sci Rep2022
32763266Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.J Hepatol2021
34921208Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis.Sci Rep2021
34403987Feeding mice a diet high in oxidized linoleic acid metabolites does not alter liver oxylipin concentrations.Prostaglandins Leukot Essent Fatty Acids2021
34685598Bile Acids Activate NLRP3 Inflammasome, Promoting Murine Liver Inflammation or Fibrosis in a Cell Type-Specific Manner.Cells2021
34107544Novel Mechanisms for Resolution of Liver Inflammation: Therapeutic Implications.Semin Liver Dis2021
34233370Insights into Nonalcoholic Fatty-Liver Disease Heterogeneity.Semin Liver Dis2021
33208407Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.Gut2021
33440159Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH.Cell Rep2021
32833053Mechanisms of nonalcoholic fatty liver disease and implications for surgery.Langenbecks Arch Surg2021
32740968The Power of Single-Cell Analysis for the Study of Liver Pathobiology.Hepatology2021
31585800MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury.Mol Ther2020
31759091Identification of actin network proteins, talin-1 and filamin-A, in circulating extracellular vesicles as blood biomarkers for human myalgic encephalomyelitis/chronic fatigue syndrome.Brain Behav Immun2020
31996485ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.JCI Insight2020
32652034A Low Ï¿-6 to Ï¿-3 PUFA Ratio (n-6:n-3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth.J Nutr2020
32923831Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH.Hepatol Commun2020
32526788The NLRP3 Inflammasome in Alcoholic and Nonalcoholic Steatohepatitis.Semin Liver Dis2020
32556367Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice.J Mol Med (Berl)2020
28279074Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?Antioxid Redox Signal2019
31832567Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints.Hepatol Commun2019
30180270NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice.Hepatology2019
31184999Human induced pluripotent stem cell-derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis.JCI Insight2019
31295147Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.J Clin Invest2019
31278377NAFLD in children: new genes, new diagnostic modalities and new drugs.Nat Rev Gastroenterol Hepatol2019
31100758Novel Drivers of the Inflammatory Response in Liver Injury and Fibrosis.Semin Liver Dis2019
30982591Extracellular vesicles, the liquid biopsy of the future.J Hepatol2019
30766966Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018.Hepatol Commun2019
30467936Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects.Pediatr Diabetes2019
28902427NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.Hepatology2018
30161179Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis.PLoS One2018
30053599Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice.Biochim Biophys Acta Mol Cell Biol Lipids2018
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Collaborators

Mie University Graduate School of Medicine
Co-authored papers 33
Mayo Clinic
Co-authored papers 23
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Children's Hospital Los Angeles
Co-authored papers 6
University of Washington
Co-authored papers 5
university of california san diego
Co-authored papers 4
Mie University Graduate School of Medicine
Co-authored papers 4
University of California San Diego
Co-authored papers 3
Escola de Administracao de Empresas - FGV, Stanford University, University of California San Diego, University of Sao Paulo, Yale School of Medicine
Co-authored papers 3
University of California San Diego (university of california san diego)
Co-authored papers 3
University of Michigan ann arbor
Co-authored papers 3
Co-authored papers 3
Charite-Universitatsmedizin Berlin
Co-authored papers 3
Pinnacle Clinical Research Center
Co-authored papers 3
Co-authored papers 3
University Clinic for Visceral Surgery and Medicine, Bern University
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Center for Liver Diseases, Inova Fairfax Hospital
Co-authored papers 2
Ann and Robert H Lurie Children's Hospital of Chicago
Co-authored papers 2
Herbert Wertheim School of Public Health, University of California San Diego
Co-authored papers 2
University of Colorado Denver
Co-authored papers 2
Haeundae Paik Hospital, Inje University College of Medicine
Co-authored papers 2
Virginia Commonwealth University
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
John Hunter Children's Hospital
Co-authored papers 1
Shiley Eye Institute, University of California
Co-authored papers 1