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Author Details

Maria Kost-Alimova
1993
80
30
PMIDPaper TitleJournal TitlePublished Year
36865221FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.bioRxiv2023
37344608Optimizing the Cell Painting assay for image-based profiling.Nat Protoc2023
37075753FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.Cell Metab2023
35732739Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy.Nature2022
35439415Phenotypic Screening for Small Molecules that Protect β-Cells from Glucolipotoxicity.ACS Chem Biol2022
35559170High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells.ACS Omega2022
34725346Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin.Nature Communications2021
33534641Predicting cell health phenotypes using image-based morphology profiling.Mol Biol Cell2021
33444290Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease.J Clin Invest2021
33176151TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.Cell Rep2020
33294858A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury.Cell Rep Med2020
31348885Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.Cell2019
31784515Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation.Nat Commun2019
30962421A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.Nat Commun2019
30898838Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers.Cancer Res2019
27560178Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.Nat Protoc2016
27260156Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.Cancer Discov2016
26061247Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.J Med Chem2016
26396593Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery.Epigenetics and Chromatin2015
25938254Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.J Vis Exp2015
26139243The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.Cancer Res2015
25119024Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.Nature2014
25352948Telomere dysfunction suppresses multiple endocrine neoplasia in mice.Genes Cancer2014
23831727Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy.Nat Cell Biol2013
22341440Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.Cell2012
22341455Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.Cell2012
21321360Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications.Blood2011
21307849Telomere dysfunction induces metabolic and mitochondrial compromise.Nature2011
21113150Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.Nature2011
19219067Horizontal transfer of tumor DNA to endothelial cells in vivo.Cell Death and Differentiation2009
18773450Microdissection molecular copy-number counting (microMCC)--unlocking cancer archives with digital PCR.Journal of Pathology2008
18230801Segmental duplications and evolutionary plasticity at tumor chromosome break-prone regions.Genome Research2008
17257397Mandatory chromosomal segment balance in aneuploid tumor cells.BMC Cancer2007
17175380Multipoint interphase FISH in childhood T-acute lymphoblastic leukemia detects subpopulations that carry different chromosome 3 aberrations.Cancer Genetics and Cytogenetics2007
17174104Modeling non-random deletions in cancer.Seminars in Cancer Biology2007
16432833Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice.International Journal of Cancer2006
17196103Array-CGH and multipoint FISH to decode complex chromosomal rearrangements.BMC Genomics2006
16364767Jumping translocation of 17q11 approximately qter and 3q25 approximately q28 duplication in a variant Philadelphia t(9;14;22)(q34;q32;q11) in a childhood chronic myelogenous leukemia.Cancer Genetics and Cytogenetics2006
16405433Multipoint interphase FISH analysis of chromosome 3 abnormalities in 28 childhood AML patients.European Journal of Haematology2006
16736500CHCHD7-PLAG1 and TCEA1-PLAG1 gene fusions resulting from cryptic, intrachromosomal 8q rearrangements in pleomorphic salivary gland adenomas.Genes Chromosomes and Cancer2006
16249810[Identification of 3q21q26 syndrome by "multipoint" interphase FISH analyses in childhood myeloid leukemia].Magyar Onkologia2005
15913951Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the "elimination test".Genomics2005
15942690CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12.International Journal of Molecular Medicine2005
15188454Microcell-mediated chromosome transfer provides evidence that polysomy promotes structural instability in tumor cell chromosomes through asynchronous replication and breakage within late-replicating regions.Genes Chromosomes and Cancer2004
12618328Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice.Cancer Letters2003
12738884Coincidence of synteny breakpoints with malignancy-related deletions on human chromosome 3.Proceedings of the National Academy of Sciences of the United States of America2003
12461651Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3.Mammalian Genome2002
12234672Mouse cytosolic and mitochondrial deoxyribonucleotidases: cDNA cloning of the mitochondrial enzyme, gene structures, chromosomal mapping and comparison with the human orthologs.Gene2002
12103363Optimisation of the degenerate oligonucleotide primed PCR (DOP-PCR) for capillary thermocycler.2002
12007195The microcell hybrid-based "elimination test" identifies a 1-Mb putative tumor-suppressor region at 3p22.2-p22.1 centromeric to the homozygous deletion region detected in lung cancer.Genes Chromosomes and Cancer2002
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