Author details

Full Name

Aaron McKenna

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37066261	GENOME REPORT: Chromosome-scale genome assembly of the African spiny mouse ( <i>Acomys cahirinus</i> ).	bioRxiv	2023
35695379	Multiplexed Assembly and Annotation of Synthetic Biology Constructs Using Long-Read Nanopore Sequencing.	ACS Synthetic Biology	2022
35452605	Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped cortical development.	Cell Syst	2022
34610329	Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice.	Dev Cell	2021
35990087	ESTIMATION OF CELL LINEAGE TREES BY MAXIMUM-LIKELIHOOD PHYLOGENETICS.	Annals of Applied Statistics	2021
34115987	Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states.	Cancer Cell	2021
32907634	Impact of industrial production system parameters on chicken microbiomes: mechanisms to improve performance and reduce Campylobacter.	Microbiome	2020
33068532	Emergence of Neuronal Diversity during Vertebrate Brain Development.	Neuron	2020
31249005	Recording development with single cell dynamic lineage tracing.	Development (Cambridge)	2019
29608178	Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain.	Nat Biotechnol	2018
29976198	FlashFry: a fast and flexible tool for large-scale CRISPR target design.	BMC Biol	2018
30257219	Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data.	Cell Rep	2018
30197638	A Review of the Effect of Management Practices on Prevalence in Poultry Farms.	Frontiers in Microbiology	2018
30374341	Comprehensive Longitudinal Microbiome Analysis of the Chicken Cecum Reveals a Shift From Competitive to Environmental Drivers and a Window of Opportunity for .	Frontiers in Microbiology	2018
28712454	CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.	Am J Hum Genet	2017
28594900	Systematic genomic and translational efficiency studies of uveal melanoma.	PLoS One	2017
27167109	A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine.	Oncotarget	2016
27229144	Whole-organism lineage tracing by combinatorial and cumulative genome editing.	Science	2016
26192918	Paired exome analysis of Barrett's esophagus and adenocarcinoma.	Nat Genet	2015
25957691	Prospective derivation of a living organoid biobank of colorectal cancer patients.	Cell	2015
26181029	Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma.	JAMA Oncol	2015
26410082	Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.	Cancer Discov	2015
24836576	Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.	Nat Med	2014
25512523	Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.	Proc Natl Acad Sci U S A	2014
24265154	MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.	Cancer Discov	2014
24265153	The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.	Cancer Discov	2014
24390348	Landscape of genomic alterations in cervical carcinomas.	Nature	2014
24434212	Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy.	Cancer Cell	2014
24323028	Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.	J Clin Oncol	2014
24366412	Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy.	Prostate Cancer Prostatic Dis	2014
24909177	Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences.	Oncogene	2014
24630729	Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.	Cell	2014
25186949	The genomic landscape of pediatric Ewing sarcoma.	Cancer Discov	2014
23334666	The genetic landscape of high-risk neuroblastoma.	Nat Genet	2013
24120142	The somatic genomic landscape of glioblastoma.	Cell	2013
23770567	Mutational heterogeneity in cancer and the search for new cancer-associated genes.	Nature	2013
24185511	Somatic mutation of CDKN1B in small intestine neuroendocrine tumors.	Nat Genet	2013
23796897	A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival.	Genes Dev	2013
23313954	Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors.	Nat Genet	2013
23633565	Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.	Proc Natl Acad Sci U S A	2013
23525077	Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.	Nat Genet	2013
23415222	Evolution and impact of subclonal mutations in chronic lymphocytic leukemia.	Cell	2013
23334667	Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.	Nat Genet	2013
23374354	Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.	Cell	2013
22820256	Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.	Nature	2012
22544022	Absolute quantification of somatic DNA alterations in human cancer.	Nat Biotechnol	2012
21798893	The mutational landscape of head and neck squamous cell carcinoma.	Science	2011
21478889	A framework for variation discovery and genotyping using next-generation DNA sequencing data.	Nat Genet	2011
21803805	ContEst: estimating cross-contamination of human samples in next-generation sequencing data.	Bioinformatics	2011
20644199	The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.	Genome Res	2010