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Author Details
Full Name
Tommi S Jaakkola
Affiliation
Massachusetts Institute of Technology
ORCID
Career Start Year
1992
Papers
37
H Index
27
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37064532
EigenFold: Generative Protein Structure Prediction with Diffusion Models.
ArXiv
2023
38076509
Removing Biases from Molecular Representations via Information Maximization.
ArXiv
2023
37433327
De novo design of protein structure and function with RFdiffusion.
Nature
2023
37231267
Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii.
Nat Chem Biol
2023
36065847
Benchmarking AlphaFold-enabled molecular docking predictions for antibiotic discovery.
Mol Syst Biol
2022
34526388
Deep learning identifies synergistic drug combinations for treating COVID-19.
Proc Natl Acad Sci U S A
2021
32302574
A Deep Learning Approach to Antibiotic Discovery.
Cell
2020
32084340
A Deep Learning Approach to Antibiotic Discovery.
Cell
2020
32243158
Current and Future Roles of Artificial Intelligence in Medicinal Chemistry Synthesis.
J Med Chem
2020
31361484
Analyzing Learned Molecular Representations for Property Prediction.
J Chem Inf Model
2019
31814400
Correction to Analyzing Learned Molecular Representations for Property Prediction.
J Chem Inf Model
2019
30746086
A graph-convolutional neural network model for the prediction of chemical reactivity.
Chem Sci
2018
30906084
Modeling Persistent Trends in Distributions.
J Am Stat Assoc
2018
28696688
Convolutional Embedding of Attributed Molecular Graphs for Physical Property Prediction.
J Chem Inf Model
2017
28573205
Prediction of Organic Reaction Outcomes Using Machine Learning.
ACS Cent Sci
2017
27456004
A synergistic DNA logic predicts genome-wide chromatin accessibility.
Genome Res
2016
24441470
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
Nat Biotechnol
2014
22689769
Lineage-based identification of cellular states and expression programs.
Bioinformatics
2012
20966006
Discovering homotypic binding events at high spatial resolution.
Bioinformatics
2010
17696603
Automated discovery of functional generality of human gene expression programs.
PLoS Comput Biol
2007
16597252
Modeling the combinatorial functions of multiple transcription factors.
J Comput Biol
2006
16873502
Semi-supervised analysis of gene expression profiles for lineage-specific development in the Caenorhabditis elegans embryo.
Bioinformatics
2006
16900145
High-resolution computational models of genome binding events.
Nat Biotechnol
2006
15998451
Validation and refinement of gene-regulatory pathways on a network of physical interactions.
Genome Biol
2005
15285891
Physical network models.
J Comput Biol
2004
12801867
K-ary clustering with optimal leaf ordering for gene expression data.
Bioinformatics
2003
12935332
Continuous representations of time-series gene expression data.
J Comput Biol
2003
12934016
Comparing the continuous representation of time-series expression profiles to identify differentially expressed genes.
Proc Natl Acad Sci U S A
2003
14555958
Computational discovery of gene modules and regulatory networks.
Nat Biotechnol
2003
11928497
Combining location and expression data for principled discovery of genetic regulatory network models.
Pac Symp Biocomput
2002
12209052
Bayesian network approach to cell signaling pathway modeling.
Sci STKE
2002
11472989
Fast optimal leaf ordering for hierarchical clustering.
Bioinformatics
2001
11262961
Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks.
Pac Symp Biocomput
2001
11572776
Serial regulation of transcriptional regulators in the yeast cell cycle.
Cell
2001
10890390
A discriminative framework for detecting remote protein homologies.
J Comput Biol
2000
10786297
Using the Fisher kernel method to detect remote protein homologies.
Proc Int Conf Intell Syst Mol Biol
1999
20725286
Binary surface-relief gratings for array illumination in digital optics.
Appl Opt
1992
1 - 37 of 37
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Co-authored papers
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