Author details

Full Name

Zhiheng Yu

Affiliation

Howard Hughes Medical Institute

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37644062	Functionalization and higher-order organization of liposomes with DNA nanostructures.	Nat Commun	2023
35338845	Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.	Mol Cell	2022
35476445	Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition.	Sci Adv	2022
36263072	The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.	bioRxiv	2022
36224386	Structure of the OMEGA nickase IsrB in complex with Ï¿RNA and target DNA.	Nature	2022
33986273	CryoEM structure of the antibacterial target PBP1b at 3.3â¿¿Ã¿ resolution.	Nat Commun	2021
33658209	Cryo-EM structures of excitatory amino acid transporter 3 visualize coupled substrate, sodium, and proton binding and transport.	Sci Adv	2021
34903670	Structure and RNA template requirements of <i>Arabidopsis</i> RNA-DEPENDENT RNA POLYMERASE 2.	Proc Natl Acad Sci U S A	2021
32581365	Structure of human GABA<sub>B</sub> receptor in an inactive state.	Nature	2020
33230314	The structural basis of Rubisco phase separation in the pyrenoid.	Nat Plants	2020
32686698	Microdomains form on the luminal face of neuronal extracellular vesicle membranes.	Sci Rep	2020
32873390	Loss of GM130 does not impair oocyte meiosis and embryo development in mice.	Biochem Biophys Res Commun	2020
32665714	Author Correction: Structure of human GABA<sub>B</sub> receptor in an inactive state.	Nature	2020
30542156	Structure of Plasmodium falciparum Rh5-CyRPA-Ripr invasion complex.	Nature	2019
31704029	Cryo-EM Structure of the Human FLCN-FNIP2-Rag-Ragulator Complex.	Cell	2019
31740855	Structure of an endosomal signaling GPCR-G protein-Î²-arrestin megacomplex.	Nat Struct Mol Biol	2019
31427728	T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.	Nat Microbiol	2019
30733444	Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.	Nat Commun	2019
29590090	Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.	Nature	2018
29950717	Cryo-EM structure of an essential Plasmodium vivax invasion complex.	Nature	2018
29539637	Integrative structure and functional anatomy of a nuclear pore complex.	Nature	2018
27916517	A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation.	Structure	2017
29146813	Structural basis of bacterial transcription activation.	Science	2017
28784753	Near-atomic resolution cryoelectron microscopy structure of the 30-fold homooligomeric SpoIIIAG channel essential to spore formation in <i>Bacillus subtilis</i>.	Proc Natl Acad Sci U S A	2017
28827185	Best practices for managing large CryoEM facilities.	J Struct Biol	2017
26314863	Correction: Structural basis for the prion-like MAVS filaments in antiviral innate immunity.	Elife	2015
24569476	Structural basis for the prion-like MAVS filaments in antiviral innate immunity.	Elife	2014
23079241	Unclosed HIV-1 capsids suggest a curled sheet model of assembly.	J Mol Biol	2013
24189638	Quantitative characterization of electron detectors for transmission electron microscopy.	J Struct Biol	2013
23761076	Electron cryotomography of ESCRT assemblies and dividing Sulfolobus cells suggests that spiraling filaments are involved in membrane scission.	Mol Biol Cell	2013
22178500	The Î³-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism.	Dev Cell	2012
19959710	Loss of oriented cell division does not initiate cyst formation.	J Am Soc Nephrol	2010
20522532	Inhibition of podocyte FAK protects against proteinuria and foot process effacement.	J Am Soc Nephrol	2010
18263604	Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.	Hum Mol Genet	2008
18836075	Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.	Proc Natl Acad Sci U S A	2008
18974761	Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.	Kidney Int	2008
18280501	Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p.	J Mol Biol	2008
17360534	Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease.	Proc Natl Acad Sci U S A	2007
16537653	Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif.	J Cell Sci	2006
17406539	Electron cryotomography sample preparation using the Vitrobot.	Nat Protoc	2006
16790429	The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells.	J Biol Chem	2006
14742446	Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.	J Biol Chem	2004

1 - 42 of 42

Jianhua Zhao

University of California san francisco

Career Start Year 2013

Number of shared co-authors 2

Sarah Keegan

Institute for Systems Genetics, New York University Langone Medical Center

Career Start Year 2013

Number of shared co-authors 9

Axel F Brilot

University of California san francisco

Career Start Year 2012

Number of shared co-authors 3

Sergei Pourmal

University of California san francisco

Career Start Year 2010

Number of shared co-authors 1

Christopher H S Aylett

Imperial College London

Career Start Year 2010

Number of shared co-authors 2

Melody G Campbell

Fred Hutchinson Cancer Center

Career Start Year 2007

Number of shared co-authors 4

Elizabeth Villa

University of California San Diego, USA Howard Hughes Medical Institute

Career Start Year 2005

Number of shared co-authors 14

Martin Beck

Max Planck Institute of Biophysics

Career Start Year 2004

Number of shared co-authors 0

Gabriel C Lander

The Scripps Research Institute

Career Start Year 2003

Number of shared co-authors 3

Yao Cong

University of Chinese Academy of Sciences

Career Start Year 2003

Number of shared co-authors 2

Wei Dai

Yuecheng District Centers for Disease Control and Prevention

Career Start Year 2003

Number of shared co-authors 2

Adam Frost

University of California San Francisco

Career Start Year 2002

Number of shared co-authors 3

Maofu Liao

Harvard Medical School

Career Start Year 2000

Number of shared co-authors 6

Kay Gr??newald

Leibniz Institute of Virology

Career Start Year 2000

Number of shared co-authors 1

Wen Jiang

Purdue University. Electronic address: .

Career Start Year 2000

Number of shared co-authors 6

Georgios Skiniotis

Stanford University School of Medicine

Career Start Year 1999

Number of shared co-authors 1

Yifan Cheng

Quantitative Bioscience Institute, University of California san francisco

Career Start Year 1997

Number of shared co-authors 7

Ohad Medalia

University of Zurich

Career Start Year 1997

Number of shared co-authors 6

Damarys Loew

Institut Curie, PSL Research University

Career Start Year 1996

Number of shared co-authors 0

J. B Heymann

Frederick National Laboratory for Cancer Research, Inc.

Career Start Year 1994

Number of shared co-authors 7

Robyn Roth

Washington University School of Medicine

Career Start Year 1993

Number of shared co-authors 0

Michael H B Stowell

University of Colorado Boulder

Career Start Year 1993

Number of shared co-authors 3

Kenji Iwasaki

Institute for Protein Research, Osaka University

Career Start Year 1990

Number of shared co-authors 1

James H Hurley

University of California Berkeley

Career Start Year 1989

Number of shared co-authors 3

Henning Stahlberg

Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne

Career Start Year 1988

Number of shared co-authors 5

David A Agard

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Career Start Year 1977

Number of shared co-authors 9

Helen R Saibil

Institute of Structural and Molecular Biology, University of London

Career Start Year 1976

Number of shared co-authors 3

Wah Chiu

Stanford University

Career Start Year 1975

Number of shared co-authors 7

Michael F Schmid

Stanford University

Career Start Year 1974

Number of shared co-authors 6

Alasdair C Steven

National Institutes of Health

Career Start Year 1974

Number of shared co-authors 7

row(s) 1 - 30 of 30

Rick K Huang

National Cancer Institute, National Institutes of Health

Co-authored papers 9

Natalie C J Strynadka

The University of British Columbia

Co-authored papers 4

Grant J Jensen

California Institute of Technology, Brigham Young University

Co-authored papers 4

Michael Jason de la Cruz

Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center

Co-authored papers 3

William J Rice

New York University Grossman School of Medicine

Co-authored papers 3

Lloyd G Cantley

Yale University School of Medicine

Co-authored papers 3

David M Sabatini

Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology

Co-authored papers 2

Oliver Fiehn

University of California davis

Co-authored papers 2

Joachim Frank

Columbia University

Co-authored papers 2

Christopher W Akey

Boston University, Chobanian and Avedisian School of Medicine

Co-authored papers 2

Wayne A Hendrickson

Columbia University

Co-authored papers 2

Tong Shen

Co-authored papers 2

Lily Jun-Shen Huang

University of Texas Southwestern Medical Center

Co-authored papers 2

Rajesh K Soni

Herbert Irving Comprehensive Cancer Center, Columbia University

Co-authored papers 2

Steven J Ludtke

Baylor College of Medicine

Co-authored papers 2

Paul A Slesinger

Friedman Brain Institute, Icahn School of Medicine at Mount Sinai

Co-authored papers 2

Javier Fernandez-Martinez

The Rockefeller University

Co-authored papers 1

Richard D Pearson

Co-authored papers 1

Jennifer L Gerton

Stowers Institute for Medical Research

Co-authored papers 1

Chen Xu

University of Massachusetts Chan Medical School

Co-authored papers 1

Martin F Jarrold

Indiana University

Co-authored papers 1

Junjie Wang

The Rockefeller University

Co-authored papers 1

Wenzhu Zhang

Dalian University of Technology

Co-authored papers 1

Manjunatha Shivaraju

Center for Regenerative Medicine, Massachusetts General Hospital

Co-authored papers 1

Ignacia Echeverria

University of California san francisco

Co-authored papers 1

Roxana Mironska

The Rockefeller University

Co-authored papers 1

Christopher Aiken

Co-authored papers 1

Bridget Carragher

Columbia University

Co-authored papers 1

Wesley I Sundquist

University of Utah School of Medicine

Co-authored papers 1

Shenping Wu

Yale University

Co-authored papers 1

1 - 30

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