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Author Details

Steven Hayward
Johns Hopkins University School of Medicine
1973
118
62
PMIDPaper TitleJournal TitlePublished Year
32129471The CD151-midkine pathway regulates the immune microenvironment in inflammatory breast cancer.J Pathol2020
31801865Kaposi's Sarcoma-Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM.J Virol2020
31341058Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression without Virion Production.J Virol2019
28566383Drug Modulators of B Cell Signaling Pathways and Epstein-Barr Virus Lytic Activation.J Virol2017
25557482Hypermethylation of the interferon regulatory factor 5 promoter in Epstein-Barr virus-associated gastric carcinoma.J Microbiol2015
26427042Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation.Oncotarget2015
26714015Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling.PLoS Pathog2015
26109723A Screen for Extracellular Signal-Regulated Kinase-Primed Glycogen Synthase Kinase 3 Substrates Identifies the p53 Inhibitor iASPP.J Virol2015
23608036Potential of protein kinase inhibitors for treating herpesvirus-associated disease.Trends Microbiol2013
24023761Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.PLoS One2013
22398289SUMO binding by the Epstein-Barr virus protein kinase BGLF4 is crucial for BGLF4 function.J Virol2012
23093938Phosphorylation of the chromatin binding domain of KSHV LANA.PLoS Pathog2012
22379092A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.J Virol2012
21447826Bortezomib induction of C/EBPβ mediates Epstein-Barr virus lytic activation in Burkitt lymphoma.Blood2011
22018239Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.Cell Host Microbe2011
21990424Comparison of humoral immune responses to Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus using a viral proteome microarray.J Infect Dis2011
21526939The Ying-Yang of the virus-host interaction: control of the DNA damage response.Future Microbiol2011
20847044De novo DNA methyltransferase DNMT3b interacts with NEDD8-modified proteins.J Biol Chem2010
19244323Protein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4.J Virol2009
17360619RNA-binding proteins that inhibit RNA virus infection.Proc Natl Acad Sci U S A2007
17911266Modulation of LMP1 protein expression by EBV-encoded microRNAs.Proc Natl Acad Sci U S A2007
17609264Manipulation of the toll-like receptor 7 signaling pathway by Epstein-Barr virus.J Virol2007
17634226The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc.J Virol2007
17688306Molecular piracy: manipulation of the ubiquitin system by Kaposi's sarcoma-associated herpesvirus.Rev Med Virol2007
17314169Kaposi's sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation.J Virol2007
16298362Multiplex PCR-based DNA array for simultaneous detection of three human herpesviruses, EVB, CMV and KSHV.Exp Mol Pathol2006
16705130Notch and Wnt signaling: mimicry and manipulation by gamma herpesviruses.Sci STKE2006
16983096Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA.Proc Natl Acad Sci U S A2006
16414987Contribution of C/EBP proteins to Epstein-Barr virus lytic gene expression and replication in epithelial cells.J Virol2006
15596820The Epstein-Barr virus replication protein BBLF2/3 provides an origin-tethering function through interaction with the zinc finger DNA binding protein ZBRK1 and the KAP-1 corepressor.J Virol2005
15951807S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding.Nat Cell Biol2005
15996546p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.Neuron2005
16051835Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen.J Virol2005
15650197Regulation of expression of the Epstein-Barr virus BamHI-A rightward transcripts.J Virol2005
15070768Inhibition of Epstein-Barr virus-induced growth proliferation by a nuclear antigen EBNA2-TAT peptide.Proc Natl Acad Sci U S A2004
15288264Viral interactions with the Notch pathway.Semin Cancer Biol2004
15316101MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription.Nucleic Acids Res2004
15507659EBNA2 is required for protection of latently Epstein-Barr virus-infected B cells against specific apoptotic stimuli.J Virol2004
14991150Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers.J Mol Med (Berl)2004
15078966CCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs during induction of the EBV lytic cycle.J Virol2004
12502863CCAAT/enhancer binding protein alpha interacts with ZTA and mediates ZTA-induced p21(CIP-1) accumulation and G(1) cell cycle arrest during the Epstein-Barr virus lytic cycle.J Virol2003
12885907Cell cycle arrest by Kaposi's sarcoma-associated herpesvirus replication-associated protein is mediated at both the transcriptional and posttranslational levels by binding to CCAAT/enhancer-binding protein alpha and p21(CIP-1).J Virol2003
14645583Lytic viral replication as a contributor to the detection of Epstein-Barr virus in breast cancer.J Virol2003
12634372A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.J Virol2003
12592400A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.Nat Med2003
12829841The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta.J Virol2003
12477864Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposi's sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activator (RTA) and RAP.J Virol2003
12111827A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling.J Neurosci Res2002
12388720Protein interactions targeting the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus to cell chromosomes.J Virol2002
12195020Epstein-Barr virus EBNA2 blocks Nur77- mediated apoptosis.Proc Natl Acad Sci U S A2002
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Collaborators

Washington University
Co-authored papers 10
Co-authored papers 7
David Geffen School of Medicine, University of California-Los Angeles
Co-authored papers 5
Eastern Virginia Medical School
Co-authored papers 3
University Laboratory Animal Resources, University of California irvine
Co-authored papers 2
Co-authored papers 2
Pepperdine University
Co-authored papers 2
Johns Hopkins School of Medicine
Co-authored papers 2
de Duve Institute, Universite catholique de Louvain
Co-authored papers 1
Cancer Research Center of Hawaii: University of Hawai'i Cancer Center.
Co-authored papers 1
Co-authored papers 1
University of Connecticut School of Medicine
Co-authored papers 1
Co-authored papers 1
University of California santa barbara
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Columbia University
Co-authored papers 1
Johns Hopkins University School of Medicine
Co-authored papers 1
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 1
Co-authored papers 1
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Co-authored papers 1
Institute of Cancer and Genomic Sciences, The University of Birmingham
Co-authored papers 1
Brigham and Women's Hospital, Blavatnik Institute, Harvard Medical School
Co-authored papers 1