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Author Details

Jianjun Shen
The University of Texas MD Anderson Cancer Center
1998
115
44
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36690626The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer.Nat Commun2023
36945532Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia.bioRxiv2023
35030986Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study.Epigenetics2022
35395077Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients.Clin Cancer Res2022
35593195Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients.Cancer Commun (Lond)2022
35810190Multi-modal molecular programs regulate melanoma cell state.Nat Commun2022
32553564Noninvasive Assessment of Epidermal Genomic Markers of UV Exposure in Skin.J Invest Dermatol2021
33652981ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer.Int J Mol Sci2021
34858481LBX2-AS1 Activates FSTL3 by Binding to Transcription Factor RARα to Foster Proliferation, Migration, and Invasion of Thyroid Cancer.Front Genet2021
34737271SPINDOC binds PARP1 to facilitate PARylation.Nat Commun2021
34508101Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.Nat Commun2021
34503086<i>Usp22</i> Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice.Cancers (Basel)2021
33986289Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.Nat Commun2021
34087996Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation.Stem Cell Res2021
32153043Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway.Cell Biochem Funct2020
31966025Multisite Evaluation of Next-Generation Methods for Small RNA Quantification.J Biomol Tech2020
31903115Musashi-1 promotes stress-induced tumor progression through recruitment of AGO2.Theranostics2020
33168647Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis.Cancer Res2020
33133260Interaction between regulatory T cells and mast cells via IL-9 and TGF-β production.Oncol Lett2020
32885167Defining the mutation signatures of DNA polymerase θ in cancer genomes.NAR Cancer2020
32997990Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription.Cell Rep2020
30290271Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus.Neurobiol Dis2019
31296163Systematic evaluation of RNA-Seq preparation protocol performance.BMC Genomics2019
31226215Structural basis of specific DNA binding by the transcription factor ZBTB24.Nucleic Acids Res2019
31043384Correction: Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral <i>env</i> RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth.Clin Cancer Res2019
30916320PRMT1 loss sensitizes cells to PRMT5 inhibition.Nucleic Acids Res2019
31086186Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung.Nat Commun2019
30718289USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.Development2019
30321403DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells.Nucleic Acids Res2019
29342309Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas.J Natl Cancer Inst2018
31938436Expression and clinical significance of HOXA5, E-cadherin, and β-catenin in cervical squamous cell carcinoma.Int J Clin Exp Pathol2018
30001199DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.Genome Biol2018
30190514Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses.Nat Commun2018
30254371Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment.Sci Rep2018
30456381CARM1 methylates MED12 to regulate its RNA-binding ability.Life Sci Alliance2018
29659998The arginine methyltransferase CARM1 represses p300â¿¢ACTâ¿¢CREMÏ¿ activity and is required for spermiogenesis.Nucleic Acids Res2018
29458327Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes.BMC Genomics2018
28965926Exposure to 4100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin.Comp Biochem Physiol C Toxicol Pharmacol2018
29276153Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration.Stem Cell Reports2018
29249668GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation.Stem Cell Reports2018
28679769Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral <i>env</i> RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth.Clin Cancer Res2017
28414320Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells.Oncogenesis2017
28112170MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes.Nat Commun2017
28297567Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer.Stem Cells Transl Med2017
28418924RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer.Oncotarget2017
28570559Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.PLoS Genet2017
28881767Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model.Oncotarget2017
28504676Developing Spindlin1 small-molecule inhibitors by using protein microarrays.Nat Chem Biol2017
26869351Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice.Cancer Prev Res (Phila)2016
27588403DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations.Oncotarget2016
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Collaborators

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Co-authored papers 33
Center for Biomedical Research Support, The University of Texas at Austin
Co-authored papers 14
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Co-authored papers 5
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Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
Samuel Oschin Cancer Center, Cedars Sinai Medical Center
Co-authored papers 4
Basic Medical College, Qingdao University
Co-authored papers 4
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Duke University School of Medicine
Co-authored papers 2
Research Unit Analytical Pathology, German Research Center for Environmental Health
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
North China Electric Power University
Co-authored papers 2
Center for Coregulator Research, Baylor College of Medicine
Co-authored papers 2
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Co-authored papers 2
Taipei Medical University
Co-authored papers 2
Roswell Park Comprehensive Cancer Center
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The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
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Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
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University of California San Diego
Co-authored papers 1
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