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Author Details

Reijo Laaksonen
1974
186
50
PMIDPaper TitleJournal TitlePublished Year
36813803Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods.Sci Rep2023
36419336Effect of Diets on Plasma and Aorta Lipidome: A Study in the apoE Knockout Mouse Model.Molecular Nutrition and Food Research2023
37834795Coronary Event Risk Test (CERT) as a Risk Predictor for the 10-Year Clinical Outcome of Patients with Peripheral Artery Disease.2023
37574027Short and medium chain acylcarnitines as markers of outcome in diabetic and non-diabetic subjects with acute coronary syndromes.2023
34417607Comparison of recent ceramide-based coronary risk prediction scores in cardiovascular disease patients.European Journal of Preventive Cardiology2022
36308332Ceramides and Phosphatidylcholines Associate with Cardiovascular Diseases in the Elderly.Clinical Chemistry2022
35365690Ceramides and phospholipids in plasma extracellular vesicles are associated with high risk of major cardiovascular events after carotid endarterectomy.Scientific Reports2022
35916742Circulating trimethylamine N-oxide levels do not predict 10-year survival in patients with or without coronary heart disease.Journal of Internal Medicine2022
35716045Plasma ceramides independently predict all-cause mortality in men aged 85.Age and Ageing2022
33483748TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies.Cardiovascular Research2022
34060615Primary cardiovascular risk prediction by LDL-cholesterol in Caucasian middle-aged and older adults: a joint analysis of three cohorts.European Journal of Preventive Cardiology2022
33624052Plasma ceramide and phospholipid-based risk score and the risk of cardiovascular death in patients after acute coronary syndrome.Eur J Prev Cardiol2022
34453528Prior myocardial infarction, coronary artery disease extent, diabetes mellitus, and CERT2 score for risk stratification in stable coronary artery disease.Eur J Prev Cardiol2022
34533314Coffee, Atrial Fibrillation, and Circulating Ceramides in Patients with Chronic Heart Failure.Journal of Agricultural and Food Chemistry2021
35919880Absolute and relative risk prediction in cardiovascular primary prevention with a modified SCORE chart incorporating ceramide-phospholipid risk score and diabetes mellitus.2021
35919088Trimethyllysine predicts all-cause and cardiovascular mortality in community-dwelling adults and patients with coronary heart disease.2021
36643994Assessment of plasma ceramides as predictor for subclinical atherosclerosis.Atheroscler Plus2021
34015112Improving 1-year mortality prediction in ACS patients using machine learning.European Heart Journal: Acute Cardiovascular Care2021
34098163Uncovering the shared lipidomic markers of subclinical osteoporosis-atherosclerosis comorbidity: The Young Finns Study.Bone2021
34337800Lipid profiles of patients with manifest coronary versus peripheral atherosclerosis - Is there a difference?J Intern Med2021
34564448A Randomized Controlled Dietary Intervention Improved the Serum Lipid Signature towards a Less Atherogenic Profile in Patients with Rheumatoid Arthritis.Metabolites2021
31209498Development and validation of a ceramide- and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients.European Heart Journal2020
32375553Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy.Journal of the American Heart Association2020
31759205Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study.Bone2020
32651186Different rates of flux through the biosynthetic pathway for long-chain versus very-long-chain sphingolipids.Journal of Lipid Research2020
33133018Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.Frontiers in Endocrinology2020
33122478Sex-specific associations of TCF7L2 variants with fasting glucose, type 2 diabetes and coronary heart disease among Turkish adults.Anatol J Cardiol2020
33058843Ceramides improve atherosclerotic cardiovascular disease risk assessment beyond standard risk factors.Clinica Chimica Acta2020
31386900Associations between specific plasma ceramides and severity of coronary-artery stenosis assessed by coronary angiography.2020
31207892Dedifferentiation of Primary Hepatocytes is Accompanied with Reorganization of Lipid Metabolism Indicated by Altered Molecular Lipid and miRNA Profiles.International Journal of Molecular Sciences2019
30203836The rs2516839 variation of USF1 gene is associated with 4-year mortality of nonagenarian women: The Vitality 90+ study.Ann Hum Genet2019
30146765hiPSC-derived hepatocytes closely mimic the lipid profile of primary hepatocytes: A future personalised cell model for studying the lipid metabolism of the liver.Journal of Cellular Physiology2019
31222113Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.Sci Rep2019
31270131New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults.J Lipid Res2019
30685440LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization study.Atherosclerosis2019
29546476Ceramide stearic to palmitic acid ratio predicts incident diabetes.Diabetologia2018
28943493The European Collaborative Project on Inflammation and Vascular Wall Remodeling in Atherosclerosis - Intravascular Ultrasound (ATHEROREMO-IVUS) study.EuroIntervention2018
29982602Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths.Eur Heart J2018
30571175Association of Plasma Ceramides With Myocardial Perfusion in Patients With Coronary Artery Disease Undergoing Stress Myocardial Perfusion Scintigraphy.Arteriosclerosis, Thrombosis, and Vascular Biology2018
29858423Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients.Journal of Lipid Research2018
29366988PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions.Atherosclerosis2018
28291223Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE mice.Scientific Reports2017
28343758Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.Eur J Vasc Endovasc Surg2017
28935963Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study.Sci Rep2017
28566218Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.Lancet Diabetes Endocrinol2017
28128285Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study.Sci Rep2017
27731410No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.Sci Rep2016
26922344Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides.Analytical and Bioanalytical Chemistry2016
27125947Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.Eur Heart J2016
27259052Fast and Accurate Construction of Confidence Intervals for Heritability.Am J Hum Genet2016
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