Author details

Full Name

Eugene C Chen

Affiliation

Department of Drug Metabolism and Pharmacokinetics, Inc.

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36630933	Evaluation of bottom-up modeling of the blood-brain barrier to improve brain penetration prediction via physiologically based pharmacokinetic modeling.	Biopharm Drug Dispos	2023
35089508	High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.	Pharm Res	2022
35488474	New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium.	Clin Pharmacol Ther	2022
31699807	Changes in Organic Anion Transporting Polypeptide Uptake in HEK293 Overexpressing Cells in the Presence and Absence of Human Plasma.	Drug Metab Dispos	2020
29768081	Unremarkable impact of Oatp inhibition on the liver concentration of fluvastatin, lovastatin and pitavastatin in wild-type and Oatp1a/1b knockout mouse.	Xenobiotica	2019
29786857	Effect of OATP1B1/1B3 Inhibitor GDC-0810 on the Pharmacokinetics of Pravastatin and Coproporphyrin I/III in Healthy Female Subjects.	J Clin Pharmacol	2018
30222362	Evaluating the Utility of Canine Mdr1 Knockout Madin-Darby Canine Kidney I Cells in Permeability Screening and Efflux Substrate Determination.	Mol Pharm	2018
30335192	Assessment of OATP transporter-mediated drug-drug interaction using physiologically-based pharmacokinetic (PBPK) modeling - a case example.	Biopharm Drug Dispos	2018
29659562	Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content.	PLoS Biol	2018
28230985	Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1).	J Med Chem	2017
26507723	The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers.	Clin Pharmacokinet	2016
25695691	Phase I Study of Vorinostat as a Radiation Sensitizer with 131I-Metaiodobenzylguanidine (131I-MIBG) for Patients with Relapsed or Refractory Neuroblastoma.	Clin Cancer Res	2015
26528626	Metformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3).	Mol Pharm	2015
25920679	Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metformin.	Mol Pharmacol	2015
24961373	OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.	Proc Natl Acad Sci U S A	2014
22231567	Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.	Pharmacogenomics J	2013
24013810	Profiling solute carrier transporters in the human blood-brain barrier.	Clin Pharmacol Ther	2013
20639304	Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.	J Pharmacol Exp Ther	2010
20859243	Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin.	Pharmacogenet Genomics	2010

1 - 19 of 19

Giovanni Bocci

The University of New Mexico School of Medicine

Career Start Year 2016

Number of shared co-authors 0

Pajaree Chariyavilaskul

Chulalongkorn University

Career Start Year 2013

Number of shared co-authors 0

Kunal S Taskar

Drug Metabolism and Pharmacokinetics

Career Start Year 2009

Number of shared co-authors 1

Lawrence Lin

University of California San Francisco

Career Start Year 2009

Number of shared co-authors 7

Jason A Sprowl

School of Pharmacy and Pharmaceutical Sciences, University at Buffalo

Career Start Year 2007

Number of shared co-authors 3

Shuiying Hu

The Ohio State University

Career Start Year 2005

Number of shared co-authors 4

Rasmus Jansson-L??fmark

Unit for Pharmacokinetics and Drug Metabolism, University of Gothenburg

Career Start Year 2005

Number of shared co-authors 2

Li Gong

Stanford University

Career Start Year 2004

Number of shared co-authors 4

Leslie W Chinn

Genentech Inc.

Career Start Year 2003

Number of shared co-authors 6

Rubin Lubomirov

Clinical Development

Career Start Year 2003

Number of shared co-authors 0

Thomas J Urban

Eshelman School of Pharmacy, University of North Carolina

Career Start Year 2003

Number of shared co-authors 11

Lie Li

Sino-French Hoffmann Institute, Guangzhou Medical University

Career Start Year 2003

Number of shared co-authors 2

Bradley L Urquhart

Schulich School of Medicine and Dentistry, Western University

Career Start Year 2003

Number of shared co-authors 0

Thomas D Nolin

University of Pittsburgh School of Pharmacy

Career Start Year 2002

Number of shared co-authors 0

Lang Li

Harbin Medical University

Career Start Year 2002

Number of shared co-authors 0

Noel Southall

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 2002

Number of shared co-authors 0

Yasuto Kido

Shionogi & Co.

Career Start Year 1999

Number of shared co-authors 7

Lara M Mangravite

Children's Hospital Oakland Research Institute

Career Start Year 1998

Number of shared co-authors 4

Alice A Gibson

The Ohio State University

Career Start Year 1997

Number of shared co-authors 2

Mary F Paine

Washington State University

Career Start Year 1996

Number of shared co-authors 1

Wei Wu

University of California

Career Start Year 1996

Number of shared co-authors 0

Matthias Schwab

and of Biochemistry and Pharmacy, University of Tuebingen

Career Start Year 1996

Number of shared co-authors 6

Anne T Nies

and University of Tuebingen, University of Tuebingen

Career Start Year 1995

Number of shared co-authors 5

Zhuyin Li

National Center for Advancing Translational Sciences, National Institutes of Health

Career Start Year 1994

Number of shared co-authors 0

Sharyn D Baker

Ohio State University

Career Start Year 1994

Number of shared co-authors 2

Alex Sparreboom

Ohio State University

Career Start Year 1994

Number of shared co-authors 5

Giuliano Ciarimboli

University Hospital Munster

Career Start Year 1989

Number of shared co-authors 2

Francois Pognan

Novartis

Career Start Year 1988

Number of shared co-authors 1

Teri E Klein

Stanford University

Career Start Year 1986

Number of shared co-authors 6

Lawrence J Lesko

Department of Pharmaceutics, University of Florida

Career Start Year 1979

Number of shared co-authors 1

row(s) 1 - 30 of 30

Kathleen M Giacomini

University of California San Francisco

Co-authored papers 13

Sook Wah Yee

University of California San Francisco

Co-authored papers 9

Ligong Chen

Tsinghua University

Co-authored papers 6

Xiaomin Liang

Gilead Sciences Inc.

Co-authored papers 5

Huan-Chieh Chien

University of California San Francisco

Co-authored papers 4

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 3

Ethan G Geier

Weill Institute for Neurosciences, University of California san francisco

Co-authored papers 3

Kari M Morrissey

Amunix Pharmaceuticals

Co-authored papers 2

Doug Stryke

University of California San Francisco

Co-authored papers 2

P??r Matsson

University of Gothenburg

Co-authored papers 2

Thomas E Ferrin

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 2

Avner Schlessinger

Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai

Co-authored papers 2

Susan J Johns

Center for Visualization, Washington State University

Co-authored papers 2

Michiaki Kubo

Co-authored papers 1

Susan L Cohn

Co-authored papers 1

Arik A Zur

Schools of Pharmacy and Medicine, University of California san francisco

Co-authored papers 1

Yong Huang

Collegeville

Co-authored papers 1

Daphne A Haas-Kogan

Co-authored papers 1

Kevan M Shokat

University of California San Francisco

Co-authored papers 1

Wolfgang Sad??e

College of Medicine, The Ohio State University

Co-authored papers 1

Ji Ha Choi

College of Medicine, Ewha Womans University

Co-authored papers 1

Joseph F Costello

University of California san francisco

Co-authored papers 1

Xujia Zhou

University of California san francisco

Co-authored papers 1

Deanna L Kroetz

University of California San Francisco

Co-authored papers 1

Steven G DuBois

Co-authored papers 1

Niklas Handin

Western Human Nutrition Research Center

Co-authored papers 1

Swati S More

Center for Drug Design, University of Minnesota

Co-authored papers 1

Richard A Castro

University of California san francisco

Co-authored papers 1

Michael A Portman

Seattle Children's Hospital

Co-authored papers 1

Bradley Pawlikowski

University of Colorado

Co-authored papers 1

1 - 30

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