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Author Details

Richard M Weinshilboum
Mayo Clinic
1968
532
94
PMIDPaper TitleJournal TitlePublished Year
36153008Cytochrome P450 Transcriptional Regulation by Testis-Specific Y-Encoded-Like Protein: Identification of Novel Upstream Transcription Factors.Drug Metab Dispos2023
37689244Epigenetic regulation of GABA catabolism in iPSC-derived neurons: The molecular links between FGF21 and histone methylation.Mol Metab2023
37438244Corrigendum to "Genetic predisposition to major depressive disorder differentially impacts alcohol consumption and high-risk drinking situations in men and women with alcohol use disorder" [Drug Alcohol Depend. 243 (2023) 109753].Drug Alcohol Depend2023
37226243Integration of multiomics data shows down regulation of mismatch repair and tubulin pathways in triple-negative chemotherapy-resistant breast tumors.Breast Cancer Res2023
36924119Dynamic assessment of serum chromogranin A and treatment response with abiraterone acetate in metastatic castration-resistant prostate cancer.Prostate2023
36779846Bayesian Machine Learning Enables Identification of Transcriptional Network Disruptions Associated with Drug-Resistant Prostate Cancer.Cancer Res2023
36469363Pharmacological Targeting of Androgen Receptor Elicits Context-Specific Effects in Estrogen Receptor-Positive Breast Cancer.Cancer Res2023
36608483Genetic predisposition to major depressive disorder differentially impacts alcohol consumption and high-risk drinking situations in men and women with alcohol use disorder.Drug Alcohol Depend2023
34667110Anastrozole Regulates Fatty Acid Synthase in Breast Cancer.Mol Cancer Ther2022
35771974Toward a Definition of "No Meaningful Benefit" From Antidepressant Treatment: An Equipercentile Analysis With Cross-Trial Validation Across Multiple Rating Scales.J Clin Psychiatry2022
35653140Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer.Clin Cancer Res2022
35734391Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response.NAR Cancer2022
35649342BETA: a comprehensive benchmark for computational drug-target prediction.Brief Bioinform2022
35861636ACE2 and TMPRSS2 SARS-CoV-2 infectivity genes: deep mutational scanning and characterization of missense variants.Hum Mol Genet2022
35752286Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.Mol Metab2022
35778714Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: a machine learning approach using clinical trial data.Arthritis Res Ther2022
35656806Proteomic Biomarkers of Sacubitril/Valsartan Treatment Response in Heart Failure With Preserved Ejection Fraction: Molecular Insights Into Sex Differences.Circ Heart Fail2022
35712048Identifying the Common Genetic Basis of Antidepressant Response.Biol Psychiatry Glob Open Sci2022
36518674Testis- specific Y-encoded- like protein 1 and cholesterol metabolism: Regulation of <i>CYP1B1</i> expression through Wnt signaling.Front Pharmacol2022
365239783D CRISPR screen in prostate cancer cells reveals PARP inhibitor sensitization through TBL1XR1-SMC3 interaction.Front Oncol2022
36135372Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment.Mol Cancer Res2022
35864174TRAF4 hyperactivates HER2 signaling and contributes to Trastuzumab resistance in HER2-positive breast cancer.Oncogene2022
36302966Single cell transcriptomics reveals distinct transcriptional responses to oxycodone and buprenorphine by iPSC-derived brain organoids from patients with opioid use disorder.Mol Psychiatry2022
36128656Glucocorticoids mediate transcriptome-wide alternative polyadenylation: Potential mechanistic and clinical implications.Clin Transl Sci2022
36263124Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.Front Pharmacol2022
36120372Plasma TNFSF10 levels associated with acamprosate treatment response in patients with alcohol use disorder.Front Pharmacol2022
35016259Genetic variants associated with acamprosate treatment response in alcohol use disorder patients: A multiple omics study.Br J Pharmacol2022
35288936Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration-Resistant Prostate Cancer.Clin Pharmacol Ther2022
35288932Evidence for machine learning guided early prediction of acute outcomes in the treatment of depressed children and adolescents with antidepressants.J Child Psychol Psychiatry2022
35041929Targeted Genotyping in Clinical Pharmacogenomics: What Is Missing?J Mol Diagn2022
35331649Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study.Genet Med2022
35330412Multi-Omics Characterization of Early- and Adult-Onset Major Depressive Disorder.J Pers Med2022
34902228Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics-Driven Machine Learning Approach.Arthritis Care Res (Hoboken)2022
35110416Genetic Polymorphisms and Correlation with Treatment-Induced Cardiotoxicity and Prognosis in Patients with Breast Cancer.Clin Cancer Res2022
32753686TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.Mol Psychiatry2021
33718782Impact of Pharmacogenomic Information on Values of Care and Quality of Life Associated with Codeine and Tramadol-Related Adverse Drug Events.Mayo Clin Proc Innov Qual Outcomes2021
33766079Correction to: Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study.Breast Cancer Res2021
33766079Correction to: Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study.Breast Cancer Res2021
33510640Selective Serotonin Reuptake Inhibitor Pharmaco-Omics: Mechanisms and Prediction.Front Pharmacol2021
33658230<i>SLCO1B1</i>: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.Drug Metab Dispos2021
34486896Genetics and antiepileptic mood stabilizer treatment response in bipolar disorder: what do we know?Pharmacogenomics2021
34848679Chronic cortisol differentially impacts stem cell-derived astrocytes from major depressive disorder patients.Transl Psychiatry2021
34535768TCF7L2 lncRNA: a link between bipolar disorder and body mass index through glucocorticoid signaling.Mol Psychiatry2021
34620827Multi-omics driven predictions of response to acute phase combination antidepressant therapy: a machine learning approach with cross-trial replication.Transl Psychiatry2021
34078650Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY).Clin Cancer Res2021
34078650Patient-Derived Xenograft Engraftment and Breast Cancer Outcomes in a Prospective Neoadjuvant Study (BEAUTY).Clin Cancer Res2021
34302059Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study.Neuropsychopharmacology2021
34101624FOXA1 overexpression suppresses interferon signaling and immune response in cancer.J Clin Invest2021
34145270Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX).NPJ Breast Cancer2021
34001842ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen and selective estrogen receptor modulator dependent fashion.Pharmacogenet Genomics2021
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Collaborators

Liewei Wang
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Co-authored papers 152
James N Ingle
Mayo Clinic
Co-authored papers 59
Matthew P Goetz
Mayo Clinic
Co-authored papers 51
Eric D Wieben
Mayo Clinic Rochester
Co-authored papers 46
Gregory D Jenkins
Mayo Clinic
Co-authored papers 43
Joanna M Biernacka
Mayo Clinic
Co-authored papers 43
Daniel J Schaid
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Michiaki Kubo
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Vera J Suman
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Mark A Frye
The Mayo Clinic
Co-authored papers 21
Brooke L Fridley
H. Lee Moffitt Cancer Center and Research Institute
Co-authored papers 20
Judy C Boughey
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Daniel K Hall-Flavin
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Co-authored papers 16
Janet E Olson
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Russ B Altman
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Japanese Foundation for Cancer Research
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Peter A Fasching
Otto-Friedrich-University Bamberg
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Lois Shepherd
Queens University
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Naveen L Pereira
Mayo Clinic
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Robert R Freimuth
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 12
John L Black
Mayo Clinic
Co-authored papers 12
Scott J Hebbring
Marshfield Clinic Research Institute
Co-authored papers 12
Mary V Relling
Departments of Pharmaceutical Sciences.
Co-authored papers 11
Fergus J Couch
Mayo Clinic
Co-authored papers 11
Mark J Ratain
University of Chicago
Co-authored papers 10
Hugues Sicotte
Mayo Clinic
Co-authored papers 9
Pedro J Caraballo
Mayo Clinic
Co-authored papers 8
Matthew J Ellis
Co-authored papers 8
Release 1.2