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Author Details

Rachel E Bennett
Massachusetts General Hospital, Harvard Medical School
2011
33
22
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36824974Endothelial Cells are Heterogeneous in Different Brain Regions and are Dramatically Altered in Alzheimer's Disease.bioRxiv2023
37553663Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells.Mol Neurodegener2023
37324243Spatial characterization of tangle-bearing neurons and ghost tangles in the human inferior temporal gyrus with three-dimensional imaging.Brain Commun2023
37208174Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease.J Neurosci2023
37376759An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature.Hum Gene Ther2023
36656755Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue.Elife2023
34957486APOE4 derived from astrocytes leads to blood-brain barrier impairment.Brain2022
33893219Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.J Neurosci2021
35531351Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.Nat Aging2021
33741591Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.Sci Adv2021
32236736PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy.Acta Neuropathol2020
33076986Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.Acta Neuropathol Commun2020
33041998Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.Front Neurol2020
32811565Tau reduction in aged mice does not impact Microangiopathy.Acta Neuropathol Commun2020
30653936Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.Neuron2019
31788496Selection of an Efficient AAV Vector for Robust CNS Transgene Expression.Mol Ther Methods Clin Dev2019
31661038[<sup>18</sup>F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series.Acta Neuropathol Commun2019
31249873Experimental evidence for the age dependence of tau protein spread in the brain.Sci Adv2019
29733334Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.Brain2018
30189209Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.Neuron2018
30413160Partial reduction of microglia does not affect tau pathology in aged mice.J Neuroinflammation2018
29472250Tau protein liquid-liquid phase separation can initiate tau aggregation.EMBO J2018
29358399Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.Proc Natl Acad Sci U S A2018
28531180Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.PLoS One2017
28500862Enhanced Tau Aggregation in the Presence of Amyloid β.Am J Pathol2017
28882310Studying tau protein propagation and pathology in the mouse brain using adeno-associated viruses.Methods Cell Biol2017
25687633Array tomography for the detection of non-dilated, injured axons in traumatic brain injury.J Neurosci Methods2015
25684677The pathophysiology of repetitive concussive traumatic brain injury in experimental models; new developments and open questions.Mol Cell Neurosci2015
24797413Acute reduction of microglia does not alter axonal injury in a mouse model of repetitive concussive traumatic brain injury.J Neurotrauma2014
23584199Human apolipoprotein E4 worsens acute axonal pathology but not amyloid-β immunoreactivity after traumatic brain injury in 3xTG-AD mice.J Neuropathol Exp Neurol2013
22343314Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury.Neurosci Lett2012
22607167Controlled cortical impact traumatic brain injury acutely disrupts wakefulness and extracellular orexin dynamics as determined by intracerebral microdialysis in mice.J Neurotrauma2012
21666502Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivity.J Neuropathol Exp Neurol2011
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Collaborators

Bradley T Hyman
Massachusetts General Hospital
Co-authored papers 22
Miwei Hu
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 7
Ashley B Robbins
University of Pennsylvania
Co-authored papers 5
Matthew P Frosch
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 5
Eloise Hudry
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 4
Leonard Petrucelli
Co-authored papers 2
Roderick Y H Lim
University of Basel
Co-authored papers 2
Sudeshna Das
Massachusetts General Hospital
Co-authored papers 2
J Gavin Daigle
Co-authored papers 2
Larisa E Kapinos
University of Basel
Co-authored papers 2
Juan C Troncoso
Co-authored papers 2
Jeffrey D Rothstein
Co-authored papers 2
Rose Pitstick
Co-authored papers 2
George A Carlson
Co-authored papers 2
Keith A Johnson
Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 1
Xinrui Cao
Harvard T.H. Chan School of Public Health
Co-authored papers 1
Sarah C Hopp
University of Texas Health Science Center San Antonio
Co-authored papers 1
Rebecca A Betensky
New York University.
Co-authored papers 1
Charles R Vanderburg
Massachusetts General Hospital and Harvard Medical School
Co-authored papers 1
Timothy Clark (CM4AI)
University of Virginia
Co-authored papers 1
Steven E Arnold
Massachusetts General Hospital
Co-authored papers 1
Tim Clark
Co-authored papers 1
Mirra Chung
Co-authored papers 1
Fyodor D Urnov
Innovative Genomics Institute, University of California berkeley
Co-authored papers 1
Anthony A Hyman
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 1
Minghui Wang
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Release 1.2