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Author Details

Marcus B Smolka
Weill Institute for Cell and Molecular Biology, Cornell University
1998
80
33
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37066328Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation.bioRxiv2023
37863026ATR takes a crack at the nuclear envelope.Mol Cell2023
37790579Phosphoribosyl modification of poly-ubiquitin chains at the <i>Legionella</i>-containing vacuole prohibiting autophagy adaptor recognition.Res Sq2023
38045423Multi-Step Control of Homologous Recombination by Mec1/ATR Ensures Robust Suppression of Gross Chromosomal Rearrangements.bioRxiv2023
37873301The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice.bioRxiv2023
37398453A TOPBP1 Allele Causing Male Infertility Uncouples XY Silencing Dynamics From Sex Body Formation.bioRxiv2023
35133274Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.Elife2022
35695711A field guide to the proteomics of post-translational modifications in DNA repair.Proteomics2022
35394024Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation.Hum Mol Genet2022
36130596DNA-PKcs promotes fork reversal and chemoresistance.Mol Cell2022
35896617Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer.Oncogene2022
35952650Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor.ACS Chem Biol2022
35133275Phosphoproteomics of ATR signaling in mouse testes.Elife2022
34018207Structural basis of TRAPPIII-mediated Rab1 activation.EMBO J2021
33491328In-depth and 3-dimensional exploration of the budding yeast phosphoproteome.EMBO Rep2021
33764556Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper-resection.EMBO J2021
33932350Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse.Mol Cell2021
34458407Fe-NTA Microcolumn Purification of Phosphopeptides from Immunoprecipitation (IP) Eluates for Mass Spectrometry Analysis.Bio Protoc2021
32176524Checkpoint Responses to DNA Double-Strand Breaks.Annu Rev Biochem2020
31839598MaXLinker: Proteome-wide Cross-link Identifications with High Specificity and Sensitivity.Mol Cell Proteomics2020
33093574Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network.Sci Rep2020
32743550Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling.NAR Cancer2020
32622269Glucosylation by the Legionella Effector SetA Promotes the Nuclear Localization of the Transcription Factor TFEB.iScience2020
32814778The Rad53<sup>CHK1/CHK2</sup>-Spt21<sup>NPAT</sup> and Tel1<sup>ATM</sup> axes couple glucose tolerance to histone dosage and subtelomeric silencing.Nat Commun2020
32725817ATR signaling in mammalian meiosis: From upstream scaffolds to downstream signaling.Environ Mol Mutagen2020
32505345Characterization of an anti-FLAG antibody binding protein in V. cholerae.Biochem Biophys Res Commun2020
31091453PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling.Cell Rep2019
31690664Deubiquitination of phosphoribosyl-ubiquitin conjugates by phosphodiesterase-domain-containing <i>Legionella</i> effectors.Proc Natl Acad Sci U S A2019
31682223Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ.Elife2019
31340146Mec1<sup>ATR</sup> Autophosphorylation and Ddc2<sup>ATRIP</sup> Phosphorylation Regulates DNA Damage Checkpoint Signaling.Cell Rep2019
31393028DNA damage kinase signaling: checkpoint and repair at 30 years.EMBO J2019
31618110Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain.Mol Biol Cell2019
30987063Next-Generation Sequencing Enables Spatiotemporal Resolution of Human Centromere Replication Timing.Genes (Basel)2019
29043653Quantitative Analysis of DNA Damage Signaling Responses to Chemical and Genetic Perturbations.Methods Mol Biol2018
30010936ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells.Nucleic Acids Res2018
29899143Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling.Genes Dev2018
27375025PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1.Oncogene2017
28228534TOPBP1<sup>Dpb11</sup> plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1<sup>Rad9</sup>.J Cell Biol2017
27165041Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast.Chromosoma2017
26811424TOPBP1 takes RADical command in recombinational DNA repair.J Cell Biol2016
26490958Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Nucleic Acids Res2016
27193190The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.Acta Neuropathol Commun2016
26765334Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation.PLoS Genet2016
25752575Phosphoproteomics reveals distinct modes of Mec1/ATR signaling during DNA replication.Mol Cell2015
26362319Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase.Genetics2015
26370502Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.J Cell Biol2015
26207098Primary Structure of a Trypsin Inhibitor (Copaifera langsdorffii Trypsin Inhibitor-1) Obtained from C. langsdorffii Seeds.J Biomol Tech2015
26113155Assembly of Slx4 signaling complexes behind DNA replication forks.EMBO J2015
25896509Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.EMBO J2015
24791994Identification of DNA damage checkpoint-dependent protein interactions in Saccharomyces cerevisiae using quantitative mass spectrometry.Methods Mol Biol2014
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Release 1.2