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Author Details

Nicholas P Restifo
National Cancer Institute, National Institutes of Health (NIH)
1985
349
133
PMIDPaper TitleJournal TitlePublished Year
37377887Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.Cancer Res Commun2023
37159663Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.Cell Rep Methods2023
37377887Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.Cancer Res Commun2023
37159663Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.Cell Rep Methods2023
34710751Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity.Curr Opin Immunol2022
36007524Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.Med2022
36002586Fine-tuning T cell function through engineered orthogonal chimeric cytokine receptors.Cell Res2022
35926468Cancer genes disfavoring T cell immunity identified via integrated systems approach.Cell Rep2022
34710751Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity.Curr Opin Immunol2022
36002586Fine-tuning T cell function through engineered orthogonal chimeric cytokine receptors.Cell Res2022
35926468Cancer genes disfavoring T cell immunity identified via integrated systems approach.Cell Rep2022
36007524Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.Med2022
33382402STING agonist promotes CAR T cell trafficking and persistence in breast cancer.J Exp Med2021
33893050Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion.Cytotherapy2021
33271120Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.Immunity2021
33382402STING agonist promotes CAR T cell trafficking and persistence in breast cancer.J Exp Med2021
34526724An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.Nature2021
33893050Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion.Cytotherapy2021
34526724An engineered IL-2 partial agonist promotes CD8<sup>+</sup> T cell stemness.Nature2021
33271120Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.Immunity2021
32231230Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.Sci Rep2020
31959727Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.J Immunother Cancer2020
32231230Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.Sci Rep2020
31996390Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.Clin Cancer Res2020
32284588Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.Nat Med2020
32516591Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.Cancer Cell2020
33234163Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.Stem Cell Res Ther2020
33125888Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy.Cell2020
33334372Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.Stem Cell Res Ther2020
31996390Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.Clin Cancer Res2020
31959727Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models.J Immunother Cancer2020
33334372Correction to: Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.Stem Cell Res Ther2020
33125888Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy.Cell2020
33234163Definitive hematopoietic stem/progenitor cells from human embryonic stem cells through serum/feeder-free organoid-induced differentiation.Stem Cell Res Ther2020
32284588Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.Nat Med2020
32516591Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies.Cancer Cell2020
30694219T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.J Clin Invest2019
31591590Developing neoantigen-targeted T cell-based treatments for solid tumors.Nat Med2019
31844254Identifying the source of tumour-infiltrating T cells.Nature2019
31628526Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation.Cancer Immunol Immunother2019
31710026Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells.J Vis Exp2019
31092734An effective mouse model for adoptive cancer immunotherapy targeting neoantigens.JCI Insight2019
30923193T cell stemness and dysfunction in tumors are triggered by a common mechanism.Science2019
30694219T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.J Clin Invest2019
31449236A Three-dimensional Thymic Culture System to Generate Murine Induced Pluripotent Stem Cell-derived Tumor Antigen-specific Thymic Emigrants.J Vis Exp2019
31405895Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells.J Exp Med2019
30778251The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.Nat Immunol2019
30714987Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.J Clin Invest2019
30882547Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma.J Immunother2019
30712990Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.Mol Cell2019
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Collaborators

University of Colorado School of Medicine
Co-authored papers 143
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 76
Co-authored papers 27
National Cancer Institute
Co-authored papers 19
Jonsson Comprehensive Cancer Center, University of California los angeles
Co-authored papers 15
National Cancer Institute
Co-authored papers 13
Center for Cancer Research, National Cancer Institute
Co-authored papers 8
Center for Cellular Engineering, NIH Clinical Center, National Institutes of Health
Co-authored papers 7
National Institute of Arthritis, National Institutes of Health
Co-authored papers 6
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
National Eye Institute, National Institutes of Health
Co-authored papers 6
Center for Cancer Research, National Cancer Institute
Co-authored papers 6
Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences
Co-authored papers 5
Science Applications International Corporation/Frederick
Co-authored papers 5
Co-authored papers 4
Co-authored papers 4
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
National Institute of Allergy and Infectious Diseases
Co-authored papers 3
Co-authored papers 3
Institute of Stem Cells and Regenerative Medicine (inStem)
Co-authored papers 3
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
National Cancer Institute, National Institutes of Health
Co-authored papers 3
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Co-authored papers 2
Queen's University
Co-authored papers 2
Center for Cancer Research National Cancer Institute, National Institutes of Health
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 2
College of Health and Life Sciences, Hamad Bin Khalifa University, Qatar Foundation
Co-authored papers 2
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
National Cancer Institute, National Institutes of Health (NIH)
Co-authored papers 2