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Author Details
Full Name
Jonathan Hinton
Affiliation
Inivata Ltd
ORCID
Career Start Year
2005
Papers
30
H Index
29
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
29543828
Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling.
PLoS One
2018
25730763
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Nat Genet
2015
26647970
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.
Nat Commun
2015
26678382
cgpPindel: Identifying Somatically Acquired Insertion and Deletion Events from Paired End Sequencing.
Curr Protoc Bioinformatics
2015
26099045
Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Nat Med
2015
26018901
Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.
Nat Genet
2015
24413735
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Nat Genet
2014
25260652
Polygenic in vivo validation of cancer mutations using transposons.
Genome Biol
2014
24429703
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
Nat Commun
2014
23770606
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma.
Nat Genet
2013
24325359
Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.
N Engl J Med
2013
24030381
Clinical and biological implications of driver mutations in myelodysplastic syndromes.
Blood
2013
23778141
Whole exome sequencing of adenoid cystic carcinoma.
J Clin Invest
2013
22608083
The life history of 21 breast cancers.
Cell
2012
22722201
The landscape of cancer genes and mutational processes in breast cancer.
Nature
2012
22608084
Mutational processes molding the genomes of 21 breast cancers.
Cell
2012
21995386
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts.
N Engl J Med
2011
21998214
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms.
Blood
2011
19837654
PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data.
Biostatistics
2010
20877315
Public data archives for genomic structural variation.
Nat Genet
2010
20164919
Signatures of mutation and selection in the cancer genome.
Nature
2010
19330029
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.
Nat Genet
2009
17436253
Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus.
Am J Hum Genet
2007
17344846
Patterns of somatic mutation in human cancer genomes.
Nature
2007
16175573
Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults.
Genes Chromosomes Cancer
2006
17088437
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.
Mol Cancer Ther
2006
17186471
Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.
Am J Hum Genet
2006
16618716
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.
Cancer Res
2006
15908952
A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer.
Nat Genet
2005
16140923
Somatic mutations of the protein kinase gene family in human lung cancer.
Cancer Res
2005
1 - 30 of 30
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Serena Nik-Zainal
Early Cancer Institute, University of Cambridge
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Rebecca Shepherd
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