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Author Details

Shwetal Mehta
Barrow Neurological Institute, St. Joseph's Hospital and Medical Center
1998
42
19
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
372879085-aminolevulinic acid, fluorescein sodium, and indocyanine green for glioma margin detection: analysis of operating wide-field and confocal microscopy in glioma models of various grades.Front Oncol2023
37991020Quisinostat is a brain-penetrant radiosensitizer in glioblastoma.JCI Insight2023
34702773A Phase 0 Trial of Ceritinib in Patients with Brain Metastases and Recurrent Glioblastoma.Clin Cancer Res2022
35619544Investigating the Interactions of Glioma Stem Cells in the Perivascular Niche at Single-Cell Resolution using a Microfluidic Tumor Microenvironment Model.Adv Sci (Weinh)2022
36550391Evaluation of two-stage designs of Phase 2 single-arm trials in glioblastoma: a systematic review.BMC Med Res Methodol2022
35174096Imaging Glioblastoma With <sup>18</sup>F-Fluciclovine Amino Acid Positron Emission Tomography.Front Oncol2022
34994746PNJ scaffolds promote microenvironmental regulation of glioblastoma stem-like cell enrichment and radioresistance.Biomater Sci2022
34740197Novel experimental model of brain arteriovenous malformations using conditional Alk1 gene deletion in transgenic mice.J Neurosurg2021
33544308Molecular Imaging of Glucose Metabolism for Intraoperative Fluorescence Guidance During Glioma Surgery.Mol Imaging Biol2021
34494550Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells.JCI Insight2021
33057180A practical method for multimodal registration and assessment of whole-brain disease burden using PET, MRI, and optical imaging.Sci Rep2020
31285369A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort.Clin Cancer Res2019
30098794A three-dimensional (3D) organotypic microfluidic model for glioma stem cells - Vascular interactions.Biomaterials2019
31215437Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer.J Transl Med2019
28821904Developmentally regulated signaling pathways in glioma invasion.Cell Mol Life Sci2018
29441325Editorial: The Role of Microenvironment in the Homing, Maintenance, and Release of Glioma Stem-Like Cells.Front Oncol2018
29718398Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas.J Neuropathol Exp Neurol2018
29681511A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.Cancer Cell2018
29798906Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients.Clin Cancer Res2018
29533842pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma.Colloids Surf B Biointerfaces2018
28040478Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells.Biochim Biophys Acta Mol Cell Res2017
29136454Immediate Label-Free Ex Vivo Evaluation of Human Brain Tumor Biopsies With Confocal Reflectance Microscopy.J Neuropathol Exp Neurol2017
28676785Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment.Front Neurol2017
28806136Harnessing OLIG2 function in tumorigenicity and plasticity to target malignant gliomas.Cell Cycle2017
28802102PNIPAAm-co-Jeffamine<sup>®</sup> (PNJ) scaffolds as in vitro models for niche enrichment of glioblastoma stem-like cells.Biomaterials2017
28614724Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway.Cell Rep2017
27396340Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway.Cell Rep2016
27626655Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells.Cell Rep2016
24948806An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.J Neurosci2014
23165259Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.Nat Rev Neurosci2012
21397859The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.Cancer Cell2011
21382551Phosphorylation state of Olig2 regulates proliferation of neural progenitors.Neuron2011
17296553Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.Neuron2007
15870297A novel role for the mitotic spindle during DNA segregation in yeast: promoting 2 microm plasmid-cohesin association.Mol Cell Biol2005
15169893Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation.Mol Cell Biol2004
15196892Site-specific recombination and partitioning systems in the stable high copy propagation of the 2-micron yeast plasmid.Prog Nucleic Acid Res Mol Biol2004
15109823Segregation of the yeast plasmid: similarities and contrasts with bacterial plasmid partitioning.Plasmid2004
14584724Selfishness in moderation: evolutionary success of the yeast plasmid.Curr Top Dev Biol2003
14517366Stable propagation of 'selfish' genetic elements.J Biosci2003
12177044The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation?J Cell Biol2002
9872416Repression of enzymes of the pentose phosphate pathway by glucose in fission yeast.FEBS Lett1998
9457874Std1, a gene involved in glucose transport in Schizosaccharomyces pombe.J Bacteriol1998
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Collaborators

Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 7
Wellcome Trust-Medical Research Council Stem Cell Institute and.
Co-authored papers 7
Co-authored papers 6
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Co-authored papers 5
Barrow Neurological Institute
Co-authored papers 4
Co-authored papers 4
Barrow Neurological Institute, St. Joseph's Hospital & Medical Center
Co-authored papers 4
Co-authored papers 3
INSERM, CNRS, Institut du Cerveau-Paris Brain Institute (ICM), Sorbonne Universite
Co-authored papers 3
Arizona State University
Co-authored papers 2
Wayne State University School of Medicine, Barbara Ann Karmanos Cancer Institute
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Co-authored papers 1
Massachusetts General Hospital, Harvard Medical School
Co-authored papers 1
Weizmann Institute of Medical Sciences
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Nencki Institute of Experimental Biology of Polish Academy of Sciences
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1
Co-authored papers 1
Innovative Genomics Institute, University of California berkeley
Co-authored papers 1
University of California san francisco
Co-authored papers 1
Genentech Inc.
Co-authored papers 1
Institute of Pediatric Hematology and Oncology
Co-authored papers 1
Massachusetts General Hospital Cancer Center, Harvard Medical School
Co-authored papers 1
University of Lausanne
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California san francisco
Co-authored papers 1