|
| 36300783 | PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. | Autophagy | 2023 |
| 36370710 | Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis. | Neuron | 2023 |
| 36300783 | PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805. | Autophagy | 2023 |
| 36206490 | PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. | Blood | 2023 |
| 36973833 | Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. | Angew Chem Int Ed Engl | 2023 |
| 37280243 | Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion. | Sci Rep | 2023 |
| 37397992 | A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. | bioRxiv | 2023 |
| 36933698 | A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators to treat Alzheimer's disease. | SLAS Discov | 2023 |
| 37500611 | A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. | Nat Commun | 2023 |
| 36917636 | Nano-DESI Mass Spectrometry Imaging of Proteoforms in Biological Tissues with High Spatial Resolution. | Anal Chem | 2023 |
| 37500611 | A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. | Nat Commun | 2023 |
| 37280243 | Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion. | Sci Rep | 2023 |
| 36973833 | Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. | Angew Chem Int Ed Engl | 2023 |
| 37397992 | A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. | bioRxiv | 2023 |
| 36917636 | Nano-DESI Mass Spectrometry Imaging of Proteoforms in Biological Tissues with High Spatial Resolution. | Anal Chem | 2023 |
| 36933698 | A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators to treat Alzheimer's disease. | SLAS Discov | 2023 |
| 36370710 | Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis. | Neuron | 2023 |
| 36206490 | PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. | Blood | 2023 |
| 34931516 | Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. | J Med Chem | 2022 |
| 36103635 | An Integrated Proteomic Strategy to Identify SHP2 Substrates. | J Proteome Res | 2022 |
| 35640720 | The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors. | J Biol Chem | 2022 |
| 35637605 | PTPN22: structure, function, and developments in inhibitor discovery with applications for immunotherapy. | Expert Opin Drug Discov | 2022 |
| 35496809 | Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells. | STAR Protoc | 2022 |
| 36336374 | High-throughput screening strategies for space-based radiation countermeasure discovery. | Life Sci Space Res (Amst) | 2022 |
| 36059958 | Exploration of beta-arrestin isoform signaling pathways in delta opioid receptor agonist-induced convulsions. | Front Pharmacol | 2022 |
| 36323237 | Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance. | Cell Metab | 2022 |
| 36197449 | Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. | J Med Chem | 2022 |
| 36969745 | Tumor Cell-Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer. | Cancer Res Commun | 2022 |
| 34931516 | Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. | J Med Chem | 2022 |
| 35640720 | The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors. | J Biol Chem | 2022 |
| 35637605 | PTPN22: structure, function, and developments in inhibitor discovery with applications for immunotherapy. | Expert Opin Drug Discov | 2022 |
| 35496809 | Purification and cryo-EM structure determination of VCP/p97 dodecamers from mammalian and bacterial cells. | STAR Protoc | 2022 |
| 36969745 | Tumor Cell-Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer. | Cancer Res Commun | 2022 |
| 36336374 | High-throughput screening strategies for space-based radiation countermeasure discovery. | Life Sci Space Res (Amst) | 2022 |
| 36103635 | An Integrated Proteomic Strategy to Identify SHP2 Substrates. | J Proteome Res | 2022 |
| 36059958 | Exploration of beta-arrestin isoform signaling pathways in delta opioid receptor agonist-induced convulsions. | Front Pharmacol | 2022 |
| 36197449 | Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. | J Med Chem | 2022 |
| 36323237 | Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance. | Cell Metab | 2022 |
| 34283806 | Systemic inhibition of PTPN22 augments anticancer immunity. | J Clin Invest | 2021 |
| 34283806 | Systemic inhibition of PTPN22 augments anticancer immunity. | J Clin Invest | 2021 |
| 33764618 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. | EMBO Rep | 2021 |
| 33714893 | Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription. | Curr Opin Chem Biol | 2021 |
| 34725361 | The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. | Nat Commun | 2021 |
| 34431504 | Functional interrogation and therapeutic targeting of protein tyrosine phosphatases. | Biochem Soc Trans | 2021 |
| 34765927 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. | iScience | 2021 |
| 33714893 | Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription. | Curr Opin Chem Biol | 2021 |
| 33764618 | PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. | EMBO Rep | 2021 |
| 34765927 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. | iScience | 2021 |
| 34431504 | Functional interrogation and therapeutic targeting of protein tyrosine phosphatases. | Biochem Soc Trans | 2021 |
| 34725361 | The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. | Nat Commun | 2021 |