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Author Details

Jeffrey N Agar
Northeastern University
1998
75
32
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37311097Structure Relaxation Approximation (SRA) for Elucidation of Protein Structures from Ion Mobility Measurements (II). Protein Complexes.J Phys Chem B2023
34383057Multimodal platform for assessing drug distribution and response in clinical trials.Neuro Oncol2022
35463966Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging.Front Mol Biosci2022
35040929massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation.Bioinformatics2022
33315366Spatial Distribution of Transcytosis Relevant Phospholipids in Response to Omega-3 Dietary Deprivation.ACS Chem Biol2021
33653954Raf promotes dimerization of the Ras G-domain with increased allosteric connections.Proc Natl Acad Sci U S A2021
33844516Increasing Top-Down Mass Spectrometry Sequence Coverage by an Order of Magnitude through Optimized Internal Fragment Generation and Assignment.Anal Chem2021
33606505Cyclic Thiosulfinates as a Novel Class of Disulfide Cleavable Cross-Linkers for Rapid Hydrogel Synthesis.Bioconjug Chem2021
34545087Peak learning of mass spectrometry imaging data using artificial neural networks.Nat Commun2021
32111867Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration.Sci Rep2020
31746669Dysregulation of very-long-chain fatty acid metabolism causes membrane saturation and induction of the unfolded protein response.Mol Biol Cell2020
31767628Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma.Cancer Res2020
32812765Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.J Am Soc Mass Spectrom2020
30745465Molecular Characterization of Prostate Cancer with Associated Gleason Score Using Mass Spectrometry Imaging.Mol Cancer Res2019
31451767A five-level classification system for proteoform identifications.Nat Methods2019
31510675Unsupervised segmentation of mass spectrometric ion images characterizes morphology of tissues.Bioinformatics2019
31249407Best practices and benchmarks for intact protein analysis for top-down mass spectrometry.Nat Methods2019
30839199Genetically Encoded Fluorescent Proteins Enable High-Throughput Assignment of Cell Cohorts Directly from MALDI-MS Images.Anal Chem2019
30932478Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data.Anal Chem2019
29253688Secretion, isotopic labeling and deglycosylation of N-acylethanolamine acid amidase for biophysical studies.Protein Expr Purif2018
30128689Rapid discrimination of pediatric brain tumors by mass spectrometry imaging.J Neurooncol2018
29851341Cyclic Thiosulfinates and Cyclic Disulfides Selectively Cross-Link Thiols While Avoiding Modification of Lone Thiols.J Am Chem Soc2018
30464169Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma.Nat Commun2018
29443976How many human proteoforms are there?Nat Chem Biol2018
29608279In Vitro Liquid Extraction Surface Analysis Mass Spectrometry (ivLESA-MS) for Direct Metabolic Analysis of Adherent Cells in Culture.Anal Chem2018
29397739ProForma: A Standard Proteoform Notation.J Proteome Res2018
28558143Parsing disease-relevant protein modifications from epiphenomena: perspective on the structural basis of SOD1-mediated ALS.J Mass Spectrom2017
29096433Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.Anal Chem2017
28558907Cold-induced aqueous acetonitrile phase separation: A salt-free way to begin quick, easy, cheap, effective, rugged, safe.J Chromatogr A2017
27744677Heavy Sugar and Heavy Water Create Tunable Intact Protein Mass Increases for Quantitative Mass Spectrometry in Any Feed and Organism.Anal Chem2016
25879418The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation.BMC Genomics2015
26542720Imaging and Mapping of Tissue Constituents at the Single-Cell Level Using MALDI MSI and Quantitative Laser Scanning Cytometry.Methods Mol Biol2015
23329739Performance comparisons of nano-LC systems, electrospray sources and LC-MS-MS platforms.J Chromatogr Sci2014
25495703QUDeX-MS: hydrogen/deuterium exchange calculation for mass spectra with resolved isotopic fine structure.BMC Bioinformatics2014
25164820Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.J Biol Chem2014
24644084The first pilot project of the consortium for top-down proteomics: a status report.Proteomics2014
24634066Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation.Proteomics2014
24328359Resolving isotopic fine structure to detect and quantify natural abundance- and hydrogen/deuterium exchange-derived isotopomers.Anal Chem2014
23927036Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage.Biochemistry2013
24373546A rapid MALDI-TOF mass spectrometry workflow for Drosophila melanogaster differential neuropeptidomics.Mol Brain2013
24091529Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging.Sci Rep2013
23919400Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase.Biochemistry2013
22632443Impaired proteasome function in sporadic amyotrophic lateral sclerosis.Amyotroph Lateral Scler2012
22821539Mass spectrometry tools for analysis of intermolecular interactions.Methods Mol Biol2012
21473592Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.Biochemistry2011
21999830Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact.Expert Rev Proteomics2011
22006323A soluble α-synuclein construct forms a dynamic tetramer.Proc Natl Acad Sci U S A2011
20303285Structural characterization of intact proteins is enhanced by prevalent fragmentation pathways rarely observed for peptides.J Am Soc Mass Spectrom2010
21098299Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis.Proc Natl Acad Sci U S A2010
20814974Memory-efficient calculation of the isotopic mass states of a molecule.Rapid Commun Mass Spectrom2010
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Co-authored papers 22
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Co-authored papers 3
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Co-authored papers 3
Brigham and Women's Hospital
Co-authored papers 3
Northwestern University
Co-authored papers 3
Barnett Institute of Chemical and Biological Analysis, Northeastern University
Co-authored papers 3
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 2
University of Oklahoma
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Genentech Inc.
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Northwestern University
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Florida State University
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University Medical Center Hamburg-Eppendorf
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EMBL-European Bioinformatics Institute (EMBL-EBI)
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University of Massachusetts Chan Medical School
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