Author details

Full Name

Sriram Venneti

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38039965	A road map for the treatment of pediatric diffuse midline glioma.	Cancer Cell	2024
37129912	Î²-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer.	Cancer Res	2023
35605606	Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma.	Neuro Oncol	2023
38045418	Single-molecule systems for detection and monitoring of plasma circulating nucleosomes and oncoproteins in Diffuse Midline Glioma.	bioRxiv	2023
37851269	Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations.	Acta Neuropathol	2023
37657463	Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.	Lancet Oncol	2023
37584601	Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.	Cancer Discov	2023
37790517	Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma.		2023
37961582	Rewiring of cortical glucose metabolism fuels human brain cancer growth.		2023
37094128	Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas.	Proc Natl Acad Sci U S A	2023
36759899	Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways.	Acta Neuropathol Commun	2023
35021084	ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization.	Cell Reports	2022
35587280	Recurrent ACVR1 mutations in posterior fossa ependymoma.	Acta Neuropathol	2022
36332566	Glioblastoma stem cell HISTArionics.		2022
36125896	H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.	J Clin Invest	2022
34644147	Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.	Sci Transl Med	2021
34162441	Autopsy findings of previously described case of diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma.	Acta Neuropathol Commun	2021
34576156	Comparative Molecular Analysis of Primary Central Nervous System Lymphomas and Matched Vitreoretinal Lymphomas by Vitreous Liquid Biopsy.	Int J Mol Sci	2021
34613815	Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.	Sci Transl Med	2021
32603316	Everolimus improves the efficacy of dasatinib in PDGFRÎ±-driven glioma.	J Clin Invest	2020
31912158	SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors.	Neuro Oncol	2020
32197665	Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma.	Acta Neuropathol Commun	2020
32601911	H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in a young adult with COVID-19-associated coagulopathy.	Acta Neuropathologica	2020
32644976	Multiple system atrophy pathology is associated with primary SjÃ¶gren's syndrome.	JCI insight	2020
32796101	Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy.	Mol Cancer Ther	2020
32568882	Incidental Massive Hydrocephalus Associated With an Unruptured Choroid Plexus Arteriovenous Malformation and Complete Agenesis of the Corpus Callosum Found in an Adult at Autopsy.	Am J Forensic Med Pathol	2020
32558936	SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors.	J Pathol	2020
32502305	cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors.	Brain Pathol	2020
30718506	SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.	Nat Commun	2019
31652923	Glutamine Metabolism in Brain Tumors.	Cancers	2019
30760578	IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.	Sci Transl Med	2019
31086175	PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism.	Nat Commun	2019
31227500	Radiosensitization by Histone H3 Demethylase Inhibition in Diffuse Intrinsic Pontine Glioma.	Clin Cancer Res	2019
31402383	Integrating ependymoma molecular subgroups into clinical trials.	Neuro-Oncology	2019
31262833	Poly Combs the Immune System: PRC2 Loss in Malignant Peripheral Nerve Sheath Tumors Can Dampen Immune Responses.	Cancer Research	2019
30948375	Pediatric Atypical Teratoid/Rhabdoid Tumors of the Brain: Identification of Metabolic Subgroups Using In Vivo <sup>1</sup>H-MR Spectroscopy.	AJNR Am J Neuroradiol	2019
30718512	CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.	Nat Commun	2019
29544532	BRAF activating mutations involving the Î²3-Î±C loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma.	Acta Neuropathol Commun	2018
32832832	Clinically Integrated Sequencing Alters Therapy in Children and Young Adults With High-Risk Glial Brain Tumors.	JCO Precis Oncol	2018
30111355	CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.	Acta Neuropathol Commun	2018
30049282	Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.	Acta Neuropathol Commun	2018
29302777	Circumscribed/non-diffuse histology confers a better prognosis in H3K27M-mutant gliomas.	Acta Neuropathol	2018
29388903	In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of <sup>18</sup>F-(2S,4R)-4-Fluoroglutamine.	Radiology	2018
28167297	Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis.	Neoplasia	2017
28955599	Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy.	Nature Biomedical Engineering	2017
28733933	Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome.	Acta Neuropathol	2017
28860053	Blood-brain barrier-adapted precision medicine therapy for pediatric brain tumors.	Transl Res	2017
29872713	Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event.	NPJ Precis Oncol	2017
27810966	Brainstem Low-Grade Gliomas in Children-Excellent Outcomes With Multimodality Therapy.	J Child Neurol	2017
28301735	Glutaminolysis: A Hallmark of Cancer Metabolism.	Annual Review of Biomedical Engineering	2017