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Author Details

Eleni M Tomazou
St. Anna Children's Cancer Research Institute (CCRI)
2007
26
15
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36462556High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-X<sub>L</sub> inhibition against Ewing sarcoma.Cancer Lett2023
37365178Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis.Nat Commun2023
36699368LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data.Bioinform Adv2022
33479542Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression.Nat Struct Mol Biol2021
34426444Quantification of Translocation-Specific ctDNA Provides an Integrating Parameter for Early Assessment of Treatment Response and Risk Stratification in Ewing Sarcoma.Clin Cancer Res2021
34050156Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.Nat Commun2021
33047515Sarcoma treatment in the era of molecular medicine.EMBO Mol Med2020
31392992EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex.Nucleic Acids Res2019
31406155Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.Cell Death Dis2019
29506020MIRA: an R package for DNA methylation-based inference of regulatory activity.Bioinformatics2018
30038364Correction: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.Cell Death Dis2018
29977059Ewing sarcoma.Nat Rev Dis Primers2018
27760381High-throughput RNAi screen in Ewing sarcoma cells identifies leucine rich repeats and WD repeat domain containing 1 (LRWD1) as a regulator of EWS-FLI1 driven cell viability.Gene2017
28134926DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.Nat Med2017
28671673EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma.Oncogene2017
27735950Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.Cell Death Dis2016
25704812Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Cell Rep2015
25625846Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs.Epigenetics2014
20062050Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution.Nat Methods2010
21222197Epigenetic regulation of pluripotency.Adv Exp Med Biol2010
20852634Quantitative comparison of genome-wide DNA methylation mapping technologies.Nat Biotechnol2010
18612301A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.Nat Biotechnol2008
18849521Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.Genome Res2008
18577705An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).Genome Res2008
18513384Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis.BMC Med Genomics2008
17680006Look who's talking too: graduates developing skills through communication.Nat Rev Genet2007
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Collaborators

St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 11
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 8
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Co-authored papers 5
Balgrist University Hospital, University of Zurich (UZH)
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Georgetown University Medical Center
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University Hospital Essen, West German Cancer Center
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UCL Cancer Institute, University College London
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PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
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The Blizard Institute, Queen Mary University of London
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University of Virginia
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Children's Cancer Research Center
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Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna
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Co-authored papers 3
Broad Institute
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St. Anna Children's Cancer Research Institute (CCRI)
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CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
University Hospital Erlangen
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Institute of Pathology, Friedrich-Alexander University Erlangen-Nurnberg (FAU)
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Children's Cancer Research Institute
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Cancer Research UK Cambridge Institute, University of Cambridge
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Hopp-Children's Cancer Center (KiTZ)
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St. Anna Children's Cancer Research Institute
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Children's Cancer Research Institute
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Heart and Lung Research Institute, University of Cambridge
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University Hospital Erlangen
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Irving Institute for Cancer Dynamics, Columbia University
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St. Anna Children's Cancer Research Institute
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