Author details

Full Name

Anthony D Whetton

Affiliation

ORCID

Career Start Year

1980

Papers

251

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37253035	Identification of curaxin as a potential new therapeutic for JAK2 V617F mutant patients.		2023
36590164	THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate.		2023
36577137	HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.	Blood	2023
36264332	High Throughput LC-MS Platform for Large Scale Screening of Bioactive Polar Lipids in Human Plasma and Serum.	Journal of Proteome Research	2022
36171271	HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.	Oncogene	2022
35701060	RadBone: bone toxicity following pelvic radiotherapy - a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecological cancers undergoing pelvic radiotherapy.	BMJ Open	2022
36292938	Multi-Omics Reveals Mechanisms of Partial Modulation of COVID-19 Dysregulation by Glucocorticoid Treatment.	International Journal of Molecular Sciences	2022
36005585	Metabolomics Markers of COVID-19 Are Dependent on Collection Wave.	Metabolites	2022
35358275	Combination of curaxin and tyrosine kinase inhibitors display enhanced killing of primitive Chronic Myeloid Leukaemia cells.	PLoS ONE	2022
34359700	Comprehensive Library Generation for Identification and Quantification of Endometrial Cancer Protein Biomarkers in Cervico-Vaginal Fluid.	Cancers	2021
33857200	OptiMissP: A dashboard to assess missingness in proteomic data-independent acquisition mass spectrometry.	PLoS One	2021
34069985	Discovery and Evaluation of Protein Biomarkers as a Signature of Wellness in Late-Stage Cancer Patients in Early Phase Clinical Trials.	Cancers	2021
33903600	Generation of a mouse SWATH-MS spectral library to quantify 10148 proteins involved in cell reprogramming.	Scientific data	2021
33578729	Metabolomic Biomarkers for the Detection of Obesity-Driven Endometrial Cancer.	Cancers	2021
33816475	An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions.	Front Cell Dev Biol	2021
34441954	Changes in the Proteome Profile of People Achieving Remission of Type 2 Diabetes after Bariatric Surgery.	Journal of Clinical Medicine	2021
34381042	Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells.	Nat Commun	2021
34771740	A Prostate Cancer Proteomics Database for SWATH-MS Based Protein Quantification.	Cancers	2021
32657586	Proteomics and Informatics for Understanding Phases and Identifying Biomarkers in COVID-19 Disease.	Journal of Proteome Research	2020
31790148	The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination.	Bioinformatics	2020
31611628	Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia.	Leukemia	2020
31657576	Proteomic Analysis of an Induced Pluripotent Stem Cell Model Reveals Strategies to Treat Juvenile Myelomonocytic Leukemia.	J Proteome Res	2020
33311975	A Paradigm to Discover Biomarkers Associated With Chronic Kidney Disease Progression.	Biomarker Insights	2020
32979164	EVI1 oncoprotein expression and CtBP1-association oscillate through the cell cycle.	Molecular Biology Reports	2020
32751940	Metabolomic Biomarkers for Detection, Prognosis and Identifying Recurrence in Endometrial Cancer.	Metabolites	2020
32746922	A consideration of publication-derived immune-related associations in Coronavirus and related lung damaging diseases.	Journal of Translational Medicine	2020
32693407	Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome.	Blood	2020
33082307	EVI1 phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal.	Cell Death and Disease	2020
32631121	Pride and prejudice - What can we learn from peer review?	Med Teach	2020
33224875	Urinary Biomarkers and Their Potential for the Non-Invasive Detection of Endometrial Cancer.	Frontiers in Oncology	2020
33117088	Application of SWATH mass spectrometry in the identification of circulating proteins does not predict future weight gain in early psychosis.	Clinical Proteomics	2020
31408348	Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients.	Journal of Proteome Research	2019
31723838	AXL Inhibition Extinguishes Primitive JAK2 Mutated Myeloproliferative Neoplasm Progenitor Cells.	HemaSphere	2019
31623106	Proteomic Biomarkers for the Detection of Endometrial Cancer.	Cancers	2019
31290668	PTMProphet: Fast and Accurate Mass Modification Localization for the Trans-Proteomic Pipeline.	J Proteome Res	2019
31455158	Oncogenic MYC amplifies mitotic perturbations.	Open Biology	2019
30691056	Data Independent Acquisition Mass Spectrometry Can Identify Circulating Proteins That Predict Future Weight Loss with a Diet and Exercise Programme.	Journal of Clinical Medicine	2019
31388184	Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel.	Br J Cancer	2019
29257138	Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches.	Leukemia	2018
29929532	Candidate plasma biomarkers for predicting ascending aortic aneurysm in bicuspid aortic valve disease.	J Cardiothorac Surg	2018
30102373	Erratum: EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.	Nucleic Acids Research	2018
29939287	EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association.	Nucleic Acids Research	2018
29437554	<i>hsa-mir183/EGR1</i>-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.	Blood	2018
27903971	Novel risk models for early detection and screening of ovarian cancer.	Oncotarget	2017
28935859	A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response.	Scientific Reports	2017
28533538	Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches.	Leukemia	2017
28665046	Features of lineage-specific hematopoietic metabolism revealed by mitochondrial proteomics.	Proteomics	2017
28664912	A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours.	Br J Cancer	2017
28617445	Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.	Cell Death Dis	2017
27683124	Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids.	Oncotarget	2016