| 36818551 | Discovery of pyrazolopyrrolidinones as potent, broad-spectrum inhibitors of <i>Leishmania</i> infection. | Front Trop Dis | 2023 |
| 37719668 | Molecular identification of phlebotomine sand flies and the harbored <i>Leishmania</i> spp. in Sokoto State, Nigeria. | Front Cell Infect Microbiol | 2023 |
| 37851179 | Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines. | Parasitol Res | 2023 |
| 37435731 | Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors. | Future Med Chem | 2023 |
| 34730959 | Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L. | J Med Chem | 2022 |
| 35709506 | Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. | J Med Chem | 2022 |
| 35745663 | Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L. | Pharmaceuticals (Basel) | 2022 |
| 36365024 | Identification of Novel Genes and Proteoforms in <i>Angiostrongylus costaricensis</i> through a Proteogenomic Approach. | Pathogens | 2022 |
| 35960688 | Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M<sup>pro</sup> and Papain-like Protease PL<sup>pro</sup> of SARS-CoV-2. | J Chem Inf Model | 2022 |
| 35188371 | Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against <i>Trypanosoma cruzi</i>. | J Med Chem | 2022 |
| 35284725 | Identification of Leucinostatins from <i>Ophiocordyceps</i> sp. as Antiparasitic Agents against <i>Trypanosoma cruzi</i>. | ACS Omega | 2022 |
| 35018373 | Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2. | bioRxiv | 2022 |
| 33466870 | An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease. | Pathogens | 2021 |
| 33787221 | A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. | ACS Chem Biol | 2021 |
| 33503071 | First report on prevalence of SARS-CoV-2 infection among health-care workers in Nicaragua. | PLoS One | 2021 |
| 33929276 | <i>Acanthamoeba</i> Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs. | Expert Rev Anti Infect Ther | 2021 |
| 34606502 | Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease. | PLoS Negl Trop Dis | 2021 |
| 34461718 | Structure-Based Optimization of Quinazolines as Cruzain and <i>Tbr</i>CATL Inhibitors. | J Med Chem | 2021 |
| 33992862 | Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases. | Bioorg Med Chem | 2021 |
| 34068119 | Dysregulation of Glycerophosphocholines in the Cutaneous Lesion Caused by <i>Leishmania major</i> in Experimental Murine Models. | Pathogens | 2021 |
| 32125159 | Peptidomimetic Vinyl Heterocyclic Inhibitors of Cruzain Effect Antitrypanosomal Activity. | J Med Chem | 2020 |
| 31876154 | Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 1. Amide Linked Analogs. | ACS Infect Dis | 2020 |
| 31876143 | Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs. | ACS Infect Dis | 2020 |
| 32094126 | The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii. | Antimicrob Agents Chemother | 2020 |
| 33140046 | A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells. | bioRxiv | 2020 |
| 33398273 | Potent <i>in vitro</i> anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. | bioRxiv | 2020 |
| 32970692 | Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole. | PLoS Negl Trop Dis | 2020 |
| 32184953 | Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors. | ACS Med Chem Lett | 2020 |
| 32433643 | Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. | PLoS Negl Trop Dis | 2020 |
| 32322173 | Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling. | Cancer Cell Int | 2020 |
| 32224991 | High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for <i>Trypanosoma cruzi</i>. | Microorganisms | 2020 |
| 31583882 | Identification of Four Amoebicidal Nontoxic Compounds by a Molecular Docking Screen of <i>Naegleria fowleri</i> Sterol ο8-ο7-Isomerase and Phenotypic Assays. | ACS Infect Dis | 2019 |
| 29559968 | <i>In Vitro</i> Efficacy of Ebselen and BAY 11-7082 Against <i>Naegleria fowleri</i>. | Front Microbiol | 2018 |
| 30138311 | The diverse roles of cysteine proteases in parasites and their suitability as drug targets. | PLoS Negl Trop Dis | 2018 |
| 30138309 | Update on drug development targeting parasite cysteine proteases. | PLoS Negl Trop Dis | 2018 |
| 30166569 | Predictions of novel Schistosoma mansoni - human protein interactions consistent with experimental data. | Sci Rep | 2018 |
| 30630278 | Impact of Single Dose Praziquantel Treatment on Schistosoma haematobium Infection among School Children in an Endemic Nigerian Community. | Korean J Parasitol | 2018 |
| 30379807 | Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms. | PLoS Negl Trop Dis | 2018 |
| 29551628 | Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri. | Exp Parasitol | 2018 |
| 29725596 | Substrate Specificity of Cysteine Proteases Beyond the S<sub>2</sub> Pocket: Mutagenesis and Molecular Dynamics Investigation of <i>Fasciola hepatica</i> Cathepsins L. | Front Mol Biosci | 2018 |
| 29688342 | Why Funding for Neglected Tropical Diseases Should Be a Global Priority. | Clin Infect Dis | 2018 |
| 29565998 | Two key cathepsins, TgCPB and TgCPL, are targeted by the vinyl sulfone inhibitor K11777 in in vitro and in vivo models of toxoplasmosis. | PLoS One | 2018 |
| 27977118 | Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast. | ACS Chem Biol | 2017 |
| 28440429 | Cathepsin B expression in colorectal cancer in a Middle East population: Potential value as a tumor biomarker for late disease stages. | Oncol Rep | 2017 |
| 28421063 | Editorial: Drug Development for Parasite-Induced Diarrheal Diseases. | Front Microbiol | 2017 |
| 29284029 | CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). | PLoS Negl Trop Dis | 2017 |
| 29281643 | 4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection. | PLoS Negl Trop Dis | 2017 |
| 28704396 | Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target. | PLoS Negl Trop Dis | 2017 |
| 28623818 | The rule of five should not impede anti-parasitic drug development. | Int J Parasitol Drugs Drug Resist | 2017 |
| 28892370 | Mass Spectrometry-Based Chemical Cartography of a Cardiac Parasitic Infection. | Anal Chem | 2017 |