Author details

Full Name

Oliver Limbo

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37276407	Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.	Proc Natl Acad Sci U S A	2023
37582161	Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.	Sci Signal	2023
35291291	Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease.	bioRxiv	2022
35971553	Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.	iScience	2022
36300787	HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway.	Elife	2022
36068229	Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.	Nat Commun	2022
34183368	A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs.	J Immunol	2021
34197737	EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.	Mol Cell	2021
32511387	Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model.	bioRxiv	2020
32540903	Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.	Science	2020
30867290	Molecular basis of chromatin remodeling by Rhp26, a yeast CSB ortholog.	Proc Natl Acad Sci U S A	2019
30348841	Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress.	Mol Cell Biol	2019
29622660	RNase H eliminates R-loops that disrupt DNA replication but is nonessential for efficient DSB repair.	EMBO Rep	2018
30104346	Mre11 complex links sister chromatids to promote repair of a collapsed replication fork.	Proc Natl Acad Sci U S A	2018
29851556	Mre11-Rad50-dependent activity of ATM/Tel1 at DNA breaks and telomeres in the absence of Nbs1.	Mol Biol Cell	2018
28922417	Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast.	PLoS Genet	2017
27037288	ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.	EMBO J	2016
26368543	Critical Function of Î³H2A in S-Phase.	PLoS Genet	2015
24493214	ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.	EMBO J	2014
25533348	Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability.	Cell Rep	2014
25512493	Regulation of the Rhp26ERCC6/CSB chromatin remodeler by a novel conserved leucine latch motif.	Proc Natl Acad Sci U S A	2014
23080121	Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.	Nucleic Acids Res	2012
21931565	Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.	PLoS Genet	2011
21441914	ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.	Nat Struct Mol Biol	2011
21098122	Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.	Mol Cell Biol	2011
20421724	Phosphorylation-regulated binding of Ctp1 to Nbs1 is critical for repair of DNA double-strand breaks.	Cell Cycle	2010
20885790	Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.	PLoS Genet	2010
20937798	Tonoplast-localized Abc2 transporter mediates phytochelatin accumulation in vacuoles and confers cadmium tolerance.	J Biol Chem	2010
20679485	BRCT domain interactions with phospho-histone H2A target Crb2 to chromatin at double-strand breaks and maintain the DNA damage checkpoint.	Mol Cell Biol	2010
19804755	Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair.	Cell	2009
18854158	Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.	Cell	2008
17936710	Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination.	Mol Cell	2007