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Author Details

Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
1982
270
78
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36861323Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE).Nucleic Acids Res2023
37961208Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glycosylase 1.bioRxiv2023
37873231Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.bioRxiv2023
37459531Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity.Proc Natl Acad Sci U S A2023
37373320UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct Role in Base Excision Repair.Int J Mol Sci2023
36971122UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridine moieties.Nucleic Acids Res2023
36888663UV irradiation remodels the specificity landscape of transcription factors.Proc Natl Acad Sci U S A2023
36650165DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer.Nat Commun2023
35190564Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins.Nat Commun2022
35773409Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.Nat Struct Mol Biol2022
36511855Cooperative interaction between AAG and UV-DDB in the removal of modified bases.Nucleic Acids Res2022
36563578Editors' note on "p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1".DNA Repair (Amst)2022
36305644The role of UV-DDB in processing 8-oxoguanine during base excision repair.Biochem Soc Trans2022
36289721Targeting Mitochondrial Function with Chemoptogenetics.Biomedicines2022
34232996Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover.Nucleic Acids Res2021
33620094Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair.Bioessays2021
33671338The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer.Int J Mol Sci2021
34805281Searching for DNA Damage: Insights From Single Molecule Analysis.Front Mol Biosci2021
34020698Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs.Arthritis Res Ther2021
33940558PARP1: Structural insights and pharmacological targets for inhibition.DNA Repair (Amst)2021
34118769The life and legacy of Sam Wilson (1939-2021).DNA Repair (Amst)2021
32542366AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.Nucleic Acids Res2020
33087275Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing.DNA Repair (Amst)2020
33087271Graphical snapshot of Samuel H. Wilson.DNA Repair (Amst)2020
33035543Mitochondrial behavior during nuclear and mitochondrial DNA repair in Trypanosoma cruzi epimastigotes.Exp Parasitol2020
32739133Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer.DNA Repair (Amst)2020
33010169The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage.Nucleic Acids Res2020
32180546Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity.Elife2020
32141475Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins.Genet Mol Biol2020
32170071Single molecule analysis reveals monomeric XPA bends DNA and undergoes episodic linear diffusion during damage search.Nat Commun2020
30445591Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers.Hum Mol Genet2019
31993494Sick mitochondria cause telomere damage: implications for disease.Mol Cell Oncol2019
31383866The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.Nat Commun2019
31399292Huntington's Disease: Astrocytes Shift to Fatty Acid Metabolism.Trends Endocrinol Metab2019
31451640Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.Proc Natl Acad Sci U S A2019
31332353Damage sensor role of UV-DDB during base excision repair.Nat Struct Mol Biol2019
31002926Oxidative stress-induced senescence markedly increases disc cell bioenergetics.Mech Ageing Dev2019
30652106Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.Microb Cell2019
28673677Studying protein-DNA interactions using atomic force microscopy.Semin Cell Dev Biol2018
29946022Single-cell mutagenic responses and cell death revealed in real time.Proc Natl Acad Sci U S A2018
30180878Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer.Breast Cancer Res2018
30451844Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.Nat Commun2018
30334244Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics.Eur Cell Mater2018
29769197Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression.Cancer Res2018
29739984Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism.Sci Rep2018
29240933Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival.Nucleic Acids Res2018
29348607Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency.Sci Rep2018
29159324DNA repair after oxidative stress: current challenges.Curr Opin Toxicol2018
27939760Rad4 recognition-at-a-distance: Physical basis of conformation-specific anomalous diffusion of DNA repair proteins.Prog Biophys Mol Biol2017
32263555Dispersed single wall carbon nanotubes do not impact mitochondria structure or function, but technical issues during analysis could yield incorrect results.J Mater Chem B2017
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Collaborators

Janine H Santos
National Institute of Environmental Health Sciences
Co-authored papers 14
Joel N Meyer
Duke University Nicholas School of the Environment.
Co-authored papers 13
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 13
Emily C Beckwitt
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 8
Nicholas P Farrell
Virginia Commonwealth University, United States of America Massey Cancer Center
Co-authored papers 7
Robert W Sobol
University of South Alabama
Co-authored papers 6
William C Copeland
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 4
Jerry Vockley
Co-authored papers 4
Astrid C Haugen
National Institute of Environmental Health Sciences
Co-authored papers 4
Leona D Samson
Massachusetts Institute of Technology
Co-authored papers 3
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 3
Timothy R Billiar
University of Pittsburgh
Co-authored papers 3
Eric S Goetzman
Co-authored papers 2
Thomas P Conrads
Women's Health Integrated Research Center, Inova Health System
Co-authored papers 2
Andrew P VanDemark
University of Pittsburgh
Co-authored papers 2
Laura J Niedernhofer
University of Minnesota
Co-authored papers 2
Jianfeng Li
Mitchell Cancer Institute, University of South Alabama
Co-authored papers 2
Douglas J Taatjes
Co-authored papers 2
Serah Choi
University Hospitals Cleveland Medical Center and Case Comprehensive Cancer Center
Co-authored papers 2
Yuxun Zhang
Co-authored papers 2
Gregory A Gibson
University of Pittsburgh
Co-authored papers 2
Brian L Hood
The Henry M. Jackson Foundation for the Advancement of Military Medicine
Co-authored papers 2
Jennifer B Collins
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 2
Richard S Paules
Co-authored papers 2
Pierre R Bushel
Co-authored papers 2
John M Kirkwood
UPMC Hillman Cancer Center
Co-authored papers 2
Paul D Robbins
University of Minnesota
Co-authored papers 2
Christopher J Bakkenist
UPMC Hillman Cancer Center, University of Pittsburgh
Co-authored papers 2
Charles J Tucker
National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 2
Thomas J Begley
University at Albany
Co-authored papers 2
Release 1.2