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Author Details

Martin Friedlander
the Scripps Research Institute
1977
126
48
PMIDPaper TitleJournal TitlePublished Year
37433773Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity.Nat Commun2023
37869029Applications of Deep Learning: Automated Assessment of Vascular Tortuosity in Mouse Models of Oxygen-Induced Retinopathy.Ophthalmol Sci2023
37335016Integrating human iPSC-derived macrophage progenitors into retinal organoids to generate a mature retinal microglial niche.Glia2023
33229343Deep learning-based classification and segmentation of retinal cavitations on optical coherence tomography images of macular telangiectasia type 2.Br J Ophthalmol2022
35611927Deletion of Tgfβ signal in activated microglia prolongs hypoxia-induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis.Glia2022
35639473Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration.JCI Insight2022
36846105Macular Telangiectasia Type 2: A Classification System Using MultiModal Imaging MacTel Project Report Number 10.Ophthalmol Sci2022
34954780Reply.Retina2022
35303433Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids.Dev Cell2022
32513667Optical coherence tomography-angiography for monitoring neovascularisations in macular telangiectasia type 2.Br J Ophthalmol2021
33654266Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder.Commun Biol2021
33926775Interferon-γ inhibits retinal neovascularization in a mouse model of ischemic retinopathy.Cytokine2021
33758422Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease.Nat Metab2021
33837246Author Correction: Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder.Commun Biol2021
33749682Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery.J Vis Exp2021
33661283Functional Relevance of Hyper-Reflectivity in Macular Telangiectasia Type 2.Invest Ophthalmol Vis Sci2021
32437334Retinal microglia are critical for subretinal neovascular formation.JCI Insight2020
32019699Beyond Performance Metrics: Automatic Deep Learning Retinal OCT Analysis Reproduces Clinical Trial Outcome.Ophthalmology2020
33106407An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization.Proc Natl Acad Sci U S A2020
33230067WITHDRAWN: Hyper-reflectivity on optical coherence tomography in macular telangiectasia type 2.Retina2020
32699277Systemic lipid dysregulation is a risk factor for macular neurodegenerative disease.Sci Rep2020
32780864CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10.Invest Ophthalmol Vis Sci2020
30484883miR-30a-5p inhibition promotes interaction of Fas<sup>+</sup> endothelial cells and FasL<sup>+</sup> microglia to decrease pathological neovascularization and promote physiological angiogenesis.Glia2019
31232702Anti-VEGF therapy: higher potency and long-lasting antagonism are not necessarily better.J Clin Invest2019
31199961The long dystrophin gene product Dp427 modulates retinal function and vascular morphology in response to age and retinal ischemia.Neurochem Int2019
31509666Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.N Engl J Med2019
30423446Metabolomics in the study of retinal health and disease.Prog Retin Eye Res2019
30292541Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.Ophthalmology2019
29190235Global Connections to Study Idiopathic Macular Telangiectasia Type 2.Retina2018
30237865Correction: Antibody targeting TSPAN12/β-catenin signaling in vasoproliferative retinopathy.Oncotarget2018
27918307VEGF regulates local inhibitory complement proteins in the eye and kidney.J Clin Invest2017
28365209Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative.Ophthalmology2017
28138561CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect.JCI Insight2017
28250457Genome-wide analyses identify common variants associated with macular telangiectasia type 2.Nat Genet2017
28356444Antibody-Mediated Inhibition of Tspan12 Ameliorates Vasoproliferative Retinopathy Through Suppression of β-Catenin Signaling.Circulation2017
29560082Antibody targeting TSPAN12/β-catenin signaling in vasoproliferative retinopathy.Oncotarget2017
28973315Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2.Invest Ophthalmol Vis Sci2017
29263301Fully automated, deep learning segmentation of oxygen-induced retinopathy images.JCI Insight2017
26974308Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.Nat Med2016
26617478Global metabolomics reveals metabolic dysregulation in ischemic retinopathy.Metabolomics2016
27644974Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation.Philos Trans A Math Phys Eng Sci2016
27834402Macrophages form functional vascular mimicry channels in vivo.Sci Rep2016
27805590Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay.J Vis Exp2016
27270778Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1.Nat Med2016
27494343CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy.Invest Ophthalmol Vis Sci2016
26880994iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study.Stem Cells Int2016
26978795Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.Elife2016
25601659Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids.Nat Commun2015
28532369Angiogenesis and Eye Disease.Annu Rev Vis Sci2015
26299572Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells.Cell Stem Cell2015
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Collaborators

Edith Aguilar
the Scripps Research Institute
Co-authored papers 46
Felicitas Bucher
Medical Center, University of Freiburg
Co-authored papers 12
Lea Scheppke
Lowy Medical Research Institute, California The Scripps Research Institute
Co-authored papers 9
Gary Siuzdak
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 8
Marcus Fruttiger
UCL Institute of Ophthalmology
Co-authored papers 7
Emily Y Chew
National Eye Institute, National Institutes of Health
Co-authored papers 7
Catherine Egan
Moorfields Eye Hospital NHS Foundation Trust
Co-authored papers 6
Marin L Gantner
Lowy Medical Research Institute
Co-authored papers 6
Melanie Bahlo
Co-authored papers 6
Rando Allikmets
Columbia University Medical Center
Co-authored papers 6
Tjebo F C Heeren
Moorfields Eye Hospital, NHS Foundation Trust
Co-authored papers 6
Kyle V Marra
the Scripps Research Institute
Co-authored papers 5
Sophia Diaz-Aguilar
The Scripps Research Institute
Co-authored papers 5
Traci E Clemons
The EMMES Corporation
Co-authored papers 4
G??nter Blobel
Howard Hughes Medical Institute, The Rockefeller University
Co-authored papers 4
Regis Fallon
Lowy Medical Research Institute
Co-authored papers 4
Sina Farsiu
Duke University
Co-authored papers 4
Robyn H Guymer
Royal Victorian Eye and Ear Hospital, the University of Melbourne
Co-authored papers 3
Frank G Holz
University of Bonn
Co-authored papers 3
Mark C Gillies
The University of Sydney Save Sight Institute
Co-authored papers 3
Julijana Ivanisevic
University of Lausanne
Co-authored papers 2
Nikolas Pontikos
Moorfields Eye Hospital, UK UCL Institute of Ophthalmology, University College London
Co-authored papers 2
Joan W Miller
Harvard Medical School
Co-authored papers 2
Robert S Ross
Co-authored papers 2
Chandra L Theesfeld
Lewis-Sigler Institute for Integrative Genomics, Princeton University
Co-authored papers 2
Tunde Peto
Queen's University Belfast
Co-authored papers 2
Fran??ois-Michel Boisvert
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
Co-authored papers 2
Clary B Clish
Broad Institute of MIT and Harvard
Co-authored papers 2
Eleonora M Lad
Duke University Medical Center
Co-authored papers 2
Martina Wallace
University College Dublin
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