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Author Details

Xueling Sim
1997
177
55
PMIDPaper TitleJournal TitlePublished Year
36658435The Singapore National Precision Medicine Strategy.Nat Genet2023
38028628Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.Front Genet2023
37591346Risk prediction models for type 2 diabetes using either fasting plasma glucose or HbA1c in Chinese, Malay, and Indians: Results from three multi-ethnic Singapore cohorts.Diabetes Res Clin Pract2023
37986948Genome-Wide Interaction Analysis with DASH Diet Score Identified Novel Loci for Systolic Blood Pressure.medRxiv2023
36963499Isocaloric Substitution of Plant-Based Protein for Animal-Based Protein and Cardiometabolic Risk Factors in a Multiethnic Asian Population.2023
36706097Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study.Diabetes Care2023
37123247A five-safes approach to a secure and scalable genomics data repository.iScience2023
37169822Prioritization of genes associated with type 2 diabetes mellitus for functional studies.2023
36991119An atlas of genetic scores to predict multi-omic traits.Nature2023
37034649Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.medRxiv2023
35084436Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes.JAMA Oncol2022
36047523Nationwide study of the characteristics of frequent attenders with multiple emergency department attendance patterns.Annals of the Academy of Medicine, Singapore2022
36107630Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans.J Clin Invest2022
35393509Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.Commun Biol2022
35390150Circulating Metabolic Biomarkers Are Consistently Associated With Type 2 Diabetes Risk in Asian and European Populations.J Clin Endocrinol Metab2022
35585913Multidisciplinary Effort to Drive Precision-Medicine for the Future.Frontiers in Digital Health2022
35585550Breast cancer risks associated with missense variants in breast cancer susceptibility genes.Genome Med2022
35513483Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.Commun Biol2022
35697829Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.Commun Biol2022
35551307Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.Nat Genet2022
35468796Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification.BMC Medicine2022
34376796Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.J Hum Genet2022
34754432Association of leukocyte telomere length with chronic kidney disease in East Asians with type 2 diabetes: a Mendelian randomization study.CKJ: Clinical Kidney Journal2021
33901219Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers.PLoS ONE2021
33846905Progress in Defining the Genetic Contribution to Type 2 Diabetes in Individuals of East Asian Ancestry.Current Diabetes Reports2021
34108472Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.Nat Commun2021
33889958Association of Genetic Variants for Plasma LRG1 With Rapid Decline in Kidney Function in Patients With Type 2 Diabetes.Journal of Clinical Endocrinology and Metabolism2021
33727701Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2021
32591784Using off-target data from whole-exome sequencing to improve genotyping accuracy, association analysis and polygenic risk prediction.Briefings in Bioinformatics2021
34670603Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals.Clin Epigenetics2021
34548093APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups.Lipids Health Dis2021
34604815Genetic discovery and risk characterization in type 2 diabetes across diverse populations.HGG Adv2021
33004401Serum acylcarnitines and amino acids and risk of type 2 diabetes in a multiethnic Asian population.BMJ Open Diabetes Research and Care2020
31769241Multiple Biomarkers Improved Prediction for the Risk of Type 2 Diabetes Mellitus in Singapore Chinese Men and Women.Diabetes and Metabolism Journal2020
32209585Association of <i>G6PD</i> variants with hemoglobin A1c and impact on diabetes diagnosis in East Asian individuals.BMJ Open Diabetes Res Care2020
32474429Cohort profile: the Singapore diabetic cohort study.BMJ Open2020
32383070Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood.Eur J Epidemiol2020
32936915Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia.J Clin Endocrinol Metab2020
33311586Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract.Commun Biol2020
32867058Diet, Physical Activity and Adiposity as Determinants of Circulating Amino Acid Levels in a Multiethnic Asian Population.Nutrients2020
32737321European polygenic risk score for prediction of breast cancer shows similar performance in Asian women.Nat Commun2020
33230300Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nat Genet2020
33120436Coffee, Black Tea, and Green Tea Consumption in Relation to Plasma Metabolites in an Asian Population.Molecular Nutrition and Food Research2020
32511069Exploring Factors Underlying Ethnic Difference in Age-related Macular Degeneration Prevalence.Ophthalmic Epidemiol2020
31548146Factors influencing communication of traditional Chinese medicine use between patients and doctors: A multisite cross-sectional study.Journal of integrative medicine2019
31600355Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.PLoS One2019
30137523Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.Journal of Clinical Endocrinology and Metabolism2019
31539074Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.JAMA Netw Open2019
31127295A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.Hum Mol Genet2019
31415580Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium.PLoS One2019
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