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Author Details
Full Name
Michael Xavier Doss
Affiliation
BioMarin Pharmaceutical Inc.
ORCID
Career Start Year
2003
Papers
40
H Index
19
Expertise
CM4AI Collaborator
Kirsten Obernier (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36348622
Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells.
Mol Ther
2022
34831333
Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research-What We Have Learnt and Not Learnt until Now.
Cells
2021
31052294
Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications.
Cells
2019
31083689
Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis.
PLoS One
2019
29079788
Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives.
Sci Rep
2017
28480311
STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation.
Mol Ther Methods Clin Dev
2017
29281682
Overexpression of Map3k7 activates sinoatrial node-like differentiation in mouse ES-derived cardiomyocytes.
PLoS One
2017
25591772
Electrophysiological characteristics of embryonic stem cell-derived cardiomyocytes are cell line-dependent.
Cell Physiol Biochem
2015
26473594
Differences in the Early Development of Human and Mouse Embryonic Stem Cells.
PLoS One
2015
24464846
A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure.
Eur J Heart Fail
2014
25010986
Fam40b is required for lineage commitment of murine embryonic stem cells.
Cell Death Dis
2014
24770696
Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
Nat Commun
2014
24723659
Unique metabolic features of stem cells, cardiomyocytes, and their progenitors.
Circ Res
2014
23542310
Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.
J Mol Cell Cardiol
2013
21617963
Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.
Stem Cell Rev Rep
2012
22815737
Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).
PLoS One
2012
22420508
Gene expression signatures defining fundamental biological processes in pluripotent, early, and late differentiated embryonic stem cells.
Stem Cells Dev
2012
21519850
Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells.
Stem Cell Rev Rep
2012
20088756
Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.
Curr Med Chem
2010
24693063
Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells.
J Stem Cells Regen Med
2010
20711519
A comparative analysis of extra-embryonic endoderm cell lines.
PLoS One
2010
20975998
eXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formation.
PLoS One
2010
20511704
Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells.
Cell Physiol Biochem
2010
20184659
Global transcriptomic analysis of murine embryonic stem cell-derived brachyury(+) (T) cells.
Genes Cells
2010
19203379
Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives.
BMC Genomics
2009
19727443
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.
PLoS One
2009
19345177
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.
Cell Stem Cell
2009
19064816
Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells.
Hypertension
2009
18772879
Generation of a double-fluorescent double-selectable Cre/loxP indicator vector for monitoring of intracellular recombination events.
Nat Protoc
2008
19088448
Entrapment of embryonic stem cells-derived cardiomyocytes in macroporous biodegradable microspheres: preparation and characterization.
Cell Physiol Biochem
2008
19112880
Human ES cell derived cardiomyocytes for cell replacement therapy: a current update.
Chin J Physiol
2008
17428332
Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes.
Genome Biol
2007
24692927
Global transcriptomic analysis of murine embryonic stem cell-derived cardiomyocytes.
J Stem Cells Regen Med
2007
17784959
Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.
Genome Biol
2007
16846026
Generation and characterization of cardiomyocytes under serum-free conditions.
Methods Mol Biol
2006
16787199
Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases.
Curr Med Chem
2006
15866224
Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases.
J Nutr Biochem
2005
16270623
An optimized embryonic stem cell model for consistent gene expression and developmental studies: a fundamental study.
Thromb Haemost
2005
15601575
Embryonic stem cells: a promising tool for cell replacement therapy.
J Cell Mol Med
2004
14765621
Distribution of C282Y and H63D mutations in the HFE gene in healthy Asian Indians and patients with thalassaemia major.
Natl Med J India
2003
1 - 40 of 40
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