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Author Details

Farrukh Afaq
1995
112
61
PMIDPaper TitleJournal TitlePublished Year
38039923Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma.Neoplasia2024
37483698Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients.Heliyon2023
38074464An integrated computational biology approach defines the crucial role of TRIP13 in pancreatic cancer.2023
37067340BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.Mol Cancer Res2023
35194944DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.Mol Oncol2022
36304424Age-Dependent Heterogeneity of Lymph Node Metastases and Survival Identified by Analysis of a National Breast Cancer Registry.2022
36430867Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics.Int J Mol Sci2022
36388691A signature of and depletion, and a link with bacterial glutamate degradation in the Kenyan colorectal cancer patients.Journal of Gastrointestinal Oncology2022
31890904Autocrine/paracrine actions of growth hormone in human melanoma cell lines.Biochem Biophys Rep2019
29314395Editorial.Photodermatol Photoimmunol Photomed2018
29044724Tea polyphenols for the prevention of UVB-induced skin cancer.Photodermatol Photoimmunol Photomed2018
28131904Potential therapeutic targets of epithelial-mesenchymal transition in melanoma.Cancer Letters2017
28063168Phytochemicals for the Prevention of Photocarcinogenesis.Photochemistry and Photobiology2017
28125044Pomegranate for Prevention and Treatment of Cancer: An Update.Molecules2017
27671819Fisetin and Its Role in Chronic Diseases.Advances in Experimental Medicine and Biology2016
26864554Phytochemicals for the Management of Melanoma.Mini Rev Med Chem2016
26517521Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.Oncotarget2016
27528504Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.Am J Pathol2016
27638049ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis.Arch Biochem Biophys2016
27725709Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype.Sci Rep2016
25169110Fisetin inhibits UVB-induced cutaneous inflammation and activation of PI3K/AKT/NFκB signaling pathways in SKH-1 hairless mice.Photochem Photobiol2015
25533330Topical application of delphinidin reduces psoriasiform lesions in the flaky skin mouse model by inducing epidermal differentiation and inhibiting inflammation.Br J Dermatol2015
25620035Prodifferentiation, anti-inflammatory and antiproliferative effects of delphinidin, a dietary anthocyanidin, in a full-thickness three-dimensional reconstituted human skin model of psoriasis.Skin Pharmacol Physiol2015
25597784Targeting drivers of melanoma with synthetic small molecules and phytochemicals.Cancer Lett2015
26299806Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells.Oncotarget2015
25094045Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch.Biochem Biophys Res Commun2014
24217507Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway.Cancer Prev Res (Phila)2014
24466036Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways.PLoS One2014
23614741Delphinidin, a dietary antioxidant, induces human epidermal keratinocyte differentiation but not apoptosis: studies in submerged and three-dimensional epidermal equivalent models.Experimental Dermatology2013
24124611Delphinidin reduces cell proliferation and induces apoptosis of non-small-cell lung cancer cells by targeting EGFR/VEGFR2 signaling pathways.PLoS One2013
23954561Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption.Toxicol Appl Pharmacol2013
24260338Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis.PLoS One2013
23942117Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein.Biochem Biophys Res Commun2013
23800058Fisetin inhibits growth, induces Gâ¿¿ /M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation.Exp Dermatol2013
23668485Chlorine induces the unfolded protein response in murine lungs and skin.Am J Respir Cell Mol Biol2013
22114764Butein induces apoptosis and inhibits prostate tumor growth in vitro and in vivo.Antioxidants and Redox Signaling2012
22335604Differential activation of signaling pathways by UVA and UVB radiation in normal human epidermal keratinocytes.Photochemistry and Photobiology2012
22820192Combined inhibition of p38 and Akt signaling pathways abrogates cyclosporine A-mediated pathogenesis of aggressive skin SCCs.Biochem Biophys Res Commun2012
21618507Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.International Journal of Cancer2012
22181855Pomegranate fruit extract inhibits UVB-induced inflammation and proliferation by modulating NF-κB and MAPK signaling pathways in mouse skin.Photochemistry and Photobiology2012
22070679Polyphenols: skin photoprotection and inhibition of photocarcinogenesis.Mini-Reviews in Medicinal Chemistry2011
21346776Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels.2011
21147060Natural agents: cellular and molecular mechanisms of photoprotection.Archives of Biochemistry and Biophysics2011
20080335Lifestyle as risk factor for cancer: Evidence from human studies.Cancer Letters2010
20946358Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.Photochemistry and Photobiology2010
20224992In vitro and in vivo effects of water extract of white cocoa tea (Camellia ptilophylla) against human prostate cancer.Pharmaceutical Research2010
20530556Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.Carcinogenesis2010
18729103Delphinidin, an anthocyanidin in pigmented fruits and vegetables, induces apoptosis and cell cycle arrest in human colon cancer HCT116 cells.Molecular Carcinogenesis2009
19320737Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin.Experimental Dermatology2009
19037088A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways.Carcinogenesis2009
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