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Author Details

Peter Van Loo
The Francis Crick Institute
2003
122
63
PMIDPaper TitleJournal TitlePublished Year
36219477Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.J Pathol2023
37828555Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.Genome Med2023
37871126Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.PLoS Comput Biol2023
37098241The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia.J Clin Oncol2023
35145300Biallelic mutations in cancer genomes reveal local mutational determinants.Nat Genet2022
35705807A pan-cancer compendium of chromosomal instability.Nature2022
35705804Signatures of copy number alterations in human cancer.Nature2022
35438189Leveraging single-cell sequencing to unravel intratumour heterogeneity and tumour evolution in human cancers.J Pathol2022
35697807Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression.Nat Biotechnol2022
36042521A genetic model for central chondrosarcoma evolution correlates with patient outcome.Genome Med2022
36376909MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution.Genome Biol2022
32449758Allele-specific multi-sample copy number segmentation in ASCAT.Bioinformatics2021
33879792An integrative analysis of the age-associated multi-omic landscape across cancers.Nat Commun2021
33762732Breast tumours maintain a reservoir of subclonal diversity during expansion.Nature2021
33508232Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.Cell2021
33782566Promises and challenges of adoptive T-cell therapies for solid tumours.Br J Cancer2021
34824211Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture.Nat Commun2021
34672959DeCiFering the subclonal composition of tumors.Cell Syst2021
34734190Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia.Nat Cancer2021
34836952Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.Nat Commun2021
34145398E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion.Oncogene2021
34282324A pan-cancer landscape of somatic mutations in non-unique regions of the human genome.Nat Biotechnol2021
33398189A practical guide to cancer subclonal reconstruction from DNA sequencing.Nat Methods2021
32694532Ethanol exposure increases mutation rate through error-prone polymerases.Nat Commun2020
32879494Pervasive chromosomal instability and karyotype order in tumour evolution.Nature2020
32866294Drivers underpinning the malignant transformation of giant cell tumour of bone.J Pathol2020
30643118Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.Nat Commun2019
30925887Translating insights into tumor evolution to clinical practice: promises and challenges.Genome Med2019
30692535Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.Nat Commun2019
29258292Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.Nature2018
29858576Recurrent rearrangements of FOS and FOSB define osteoblastoma.Nat Commun2018
29906452Universal Patterns of Selection in Cancer and Somatic Tissues.Cell2018
30041675Timing somatic events in the evolution of cancer.Genome Biol2018
30010265Association between crural vessel patency and successful transmetatarsal amputation: a single centre experience.S Afr J Surg2018
30497530Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations.Genome Med2018
30374075Neutral tumor evolution?Nat Genet2018
30559362Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.Nat Commun2018
30327465Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.Nat Commun2018
29662167Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.Nat Genet2018
29656894Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.Cell2018
27062498Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution.Br J Haematol2017
28270531Principles of Reconstructing the Subclonal Architecture of Cancers.Cold Spring Harb Perspect Med2017
28445469Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.Nature2017
28445112Tracking the Evolution of Non-Small-Cell Lung Cancer.N Engl J Med2017
29107330Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution.Cell2017
29056346Universal Patterns of Selection in Cancer and Somatic Tissues.Cell2017
29089486Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors.Nat Commun2017
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
28810143Genomic Evolution of Breast Cancer Metastasis and Relapse.Cancer Cell2017
28643781Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma.Nat Commun2017
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Michael R Stratton
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Keiran Raine
Wellcome Sanger Institute
Co-authored papers 25
Adam Butler
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Jon Teague
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Moores Cancer Center, university of california san diego
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Wellcome Sanger Institute
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Phillip A Futreal
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Sarah O'Meara
Clinical Research Facility, Mercy University Hospital
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Susanna L Cooke
Institute of Cancer Sciences, University of Glasgow
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Vessela N Kristensen
Faculty of Clinical Medicine, University of Oslo
Co-authored papers 13
Yves Moreau
KU Leuven - University of Leuven
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Jonathan Hinton
Inivata Ltd
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Charles Swanton
Francis Crick Institute
Co-authored papers 12
Maxime Tarabichi
ULB-Cancer Research Center (U-CRC), Universite Libre de Bruxelles
Co-authored papers 12
Adrienne M Flanagan
University College London, UCL Cancer Institute
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Moritz Gerstung
German Cancer Research Centre DKFZ
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Manasa Ramakrishna
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Jonas Demeulemeester
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Ultan McDermott
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