|
| 33332995 | Inflammatory Endotype-associated Airway Microbiome in Chronic Obstructive Pulmonary Disease Clinical Stability and Exacerbations: A Multicohort Longitudinal Analysis. | Am J Respir Crit Care Med | 2021 |
| 33674782 | Expanding the drug discovery space with predicted metabolite-target interactions. | Commun Biol | 2021 |
| 34702186 | Correction to: Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK2140944). | BMC Microbiol | 2021 |
| 34130619 | Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK140944). | BMC Microbiol | 2021 |
| 32483366 | PICRUSt2 for prediction of metagenome functions. | Nat Biotechnol | 2020 |
| 31802667 | The Microbiome Factor in Drug Discovery and Development. | Chem Res Toxicol | 2020 |
| 31818823 | In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure Infections. | Antimicrob Agents Chemother | 2020 |
| 32719402 | Multi-omic meta-analysis identifies functional signatures of airway microbiome in chronic obstructive pulmonary disease. | ISME J | 2020 |
| 32664956 | The sputum microbiome is distinct between COPD and health, independent of smoking history. | Respir Res | 2020 |
| 32359474 | Microbiome Metabolite Mimics Accelerate Drug Discovery. | Trends Mol Med | 2020 |
| 31170986 | Airway host-microbiome interactions in chronic obstructive pulmonary disease. | Respir Res | 2019 |
| 31836714 | Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients. | Nat Commun | 2019 |
| 31217489 | Shared Molecular Signatures Across Neurodegenerative Diseases and Herpes Virus Infections Highlights Potential Mechanisms for Maladaptive Innate Immune Responses. | Sci Rep | 2019 |
| 29269441 | Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study. | Thorax | 2018 |
| 29386298 | Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations. | Thorax | 2018 |
| 29321020 | Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets. | BMC Syst Biol | 2018 |
| 30815546 | Gut microbiome differences between metformin- and liraglutide-treated T2DM subjects. | Endocrinol Diabetes Metab | 2017 |
| 26916596 | Human microbial metabolites as a source of new drugs. | Drug Discov Today | 2016 |
| 26917613 | Lung microbiome dynamics in COPD exacerbations. | Eur Respir J | 2016 |
| 25348524 | Bacterial resistance to leucyl-tRNA synthetase inhibitor GSK2251052 develops during treatment of complicated urinary tract infections. | Antimicrob Agents Chemother | 2015 |
| 26642067 | Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery. | PLoS One | 2015 |
| 26709835 | Selective Spectrum Antibiotic Modulation of the Gut Microbiome in Obesity and Diabetes Rodent Models. | PLoS One | 2015 |
| 25740547 | New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource. | Sci Rep | 2015 |
| 25487798 | Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase. | Antimicrob Agents Chemother | 2015 |
| 24586911 | HIV-1 transmission patterns in antiretroviral therapy-naïve, HIV-infected North Americans based on phylogenetic analysis by population level and ultra-deep DNA sequencing. | PLoS One | 2014 |
| 24988476 | Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus. | PLoS One | 2014 |
| 25092471 | No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank. | BMC Res Notes | 2014 |
| 23563424 | Translating the human microbiome. | Nat Biotechnol | 2013 |
| 24098102 | Target prediction for an open access set of compounds active against Mycobacterium tuberculosis. | PLoS Comput Biol | 2013 |
| 24086587 | Host response to respiratory bacterial pathogens as identified by integrated analysis of human gene expression data. | PLoS One | 2013 |
| 24244970 | Modulating the human gut microbiome as an emerging therapeutic paradigm. | Sci Prog | 2013 |
| 23602889 | Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development. | Toxicol Appl Pharmacol | 2013 |
| 22432004 | Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis. | PLoS One | 2012 |
| 22445903 | Data mining the human gut microbiota for therapeutic targets. | Brief Bioinform | 2012 |
| 21277381 | Computational biology approaches for selecting host-pathogen drug targets. | Drug Discov Today | 2011 |
| 21746949 | Comparative genomics of Klebsiella pneumoniae strains with different antibiotic resistance profiles. | Antimicrob Agents Chemother | 2011 |
| 21208444 | Phylogenomics of phosphoinositide lipid kinases: perspectives on the evolution of second messenger signaling and drug discovery. | BMC Evol Biol | 2011 |
| 20124449 | Molecular evolutionary analysis of cancer cell lines. | Mol Cancer Ther | 2010 |
| 20485427 | Thousands of chemical starting points for antimalarial lead identification. | Nature | 2010 |
| 19519485 | Computational biology in anti-tuberculosis drug discovery. | Infect Disord Drug Targets | 2009 |
| 18366743 | The evolution of core proteins involved in microRNA biogenesis. | BMC Evol Biol | 2008 |
| 18801459 | Novel drug target strategies against Mycobacterium tuberculosis. | Curr Opin Microbiol | 2008 |
| 17655757 | Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. | BMC Infect Dis | 2007 |
| 17727328 | The micro RNA target paradigm: a fundamental and polymorphic control layer of cellular expression. | Expert Opin Biol Ther | 2007 |
| 16816197 | Phylogenomic and biochemical characterization of three Legionella pneumophila polypeptide deformylases. | J Bacteriol | 2006 |
| 15837603 | A computational view of microRNAs and their targets. | Drug Discov Today | 2005 |
| 16189113 | Molecular evolution perspectives on intraspecific lateral DNA transfer of topoisomerase and gyrase loci in Streptococcus pneumoniae, with implications for fluoroquinolone resistance development and spread. | Antimicrob Agents Chemother | 2005 |
| 15112225 | Phylogeny of gamma-proteobacteria: resolution of one branch of the universal tree? | Bioessays | 2004 |
| 15476560 | Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs. | BMC Evol Biol | 2004 |
| 15019585 | Evidence from the evolutionary analysis of nucleotide sequences for a recombinant history of SARS-CoV. | Infect Genet Evol | 2004 |