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Author Details

Candelaria Gomez-Manzano
The University of Texas M.D. Anderson Cancer Center
1990
125
43
PMIDPaper TitleJournal TitlePublished Year
37603323Development of a rabbit human glioblastoma model for testing of endovascular selective intra-arterial infusion (ESIA) of novel stem cell-based therapeutics.Neuro Oncol2024
37379361Adjuvant Therapy with Oncolytic Adenovirus Delta-24-RGDOX After Intratumoral Adoptive T-cell Therapy Promotes Antigen Spread to Sustain Systemic Antitumor Immunity.Cancer Res Commun2023
37188783Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial.Nat Med2023
34965961Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory.Mol Cancer Ther2022
35767439Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma.N Engl J Med2022
35580289A Window of Opportunity to Overcome Therapeutic Failure in Neuro-Oncology.Am Soc Clin Oncol Educ Book2022
35702422Remission of liquid tumors and SARS-CoV-2 infection: A literature review.Mol Ther Oncolytics2022
35393952Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas.JCI Insight2022
35902132Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.J Immunother Cancer2022
33376098Delta-24-RGD, an Oncolytic Adenovirus, Increases Survival and Promotes Proinflammatory Immune Landscape Remodeling in Models of AT/RT and CNS-PNET.Clin Cancer Res2021
33795384Current strategies to circumvent the antiviral immunity to optimize cancer virotherapy.J Immunother Cancer2021
34888488Erratum: miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs.Arch Clin Biomed Res2021
34450587Characterization of patient-derived bone marrow human mesenchymal stem cells as oncolytic virus carriers for the treatment of glioblastoma.J Neurosurg2021
34214494Hitchhiking to brain tumours: stem cell delivery of oncolytic viruses.Lancet Oncol2021
34059921An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus.Neuro Oncol2021
34281988CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models.J Immunother Cancer2021
32905473miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs.Arch Clin Biomed Res2020
33231254Endovascular Selective Intra-Arterial Infusion of Mesenchymal Stem Cells Loaded With Delta-24 in a Canine Model.Neurosurgery2020
31138805The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models.Nat Commun2019
31608328GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory.Neurooncol Adv2019
31348516Antitumor immune response during glioma virotherapy.Neuro Oncol2019
31455679Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.Clin Cancer Res2019
31036068Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models.Acta Neuropathol Commun2019
29088386Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients.Neurosurgery2018
29987215Oncolytic Viruses as Therapeutic Tools for Pediatric Brain Tumors.Cancers (Basel)2018
29635349Linking inflammation and cancer: the unexpected SYK world.Neuro Oncol2018
29432077Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.J Clin Oncol2018
29594041DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report.Front Oncol2018
28760776TIE2 Associates with Caveolae and Regulates Caveolin-1 To Promote Their Nuclear Translocation.Mol Cell Biol2017
29166609GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma.Cell Rep2017
28944168Normalizing Tumoral Vessels to Treat Cancer: An Out-of-the-Box Strategy Involving TIE2 Pathway.Transl Cancer Res2017
28566332Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.Cancer Res2017
26951384Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.Neuro Oncol2016
27669421Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells.PLoS One2016
27757426TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.Sci Adv2016
27121320Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma.Oncotarget2016
27515302Tumor-associated stromal cells as key contributors to the tumor microenvironment.Breast Cancer Res2016
27093696Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens.PLoS One2016
26910374Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas.Oncotarget2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
25619840C-Jun N-terminal kinases are required for oncolytic adenovirus-mediated autophagy.Oncogene2015
26661633Delta-24-RGD Induces Cytotoxicity of Glioblastoma Spheroids in Three Dimensional PEG Microwells.IEEE Trans Nanobioscience2015
25863716Oncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpoints.Curr Opin Virol2015
25925380Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model.Neoplasia2015
24737304The oncolytic adenovirus ο24-RGD in combination with cisplatin exerts a potent anti-osteosarcoma activity.J Bone Miner Res2014
25002413Intratumoral heterogeneity and intraclonal plasticity: from warburg to oxygen and back again.Neuro Oncol2014
24809734Anti-vascular endothelial growth factor therapy-induced glioma invasion is associated with accumulation of Tie2-expressing monocytes.Oncotarget2014
24827739Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.PLoS One2014
23632480Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells.Br J Cancer2013
21948473Targeting brain tumor stem cells with oncolytic adenoviruses.Methods Mol Biol2012
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Collaborators

The University of Texas M.D. Anderson Cancer Center
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CIMA-Universidad de Navarra
Co-authored papers 56
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Co-authored papers 41
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Co-authored papers 34
Center for Applied Medical Research.
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Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine
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MD Anderson Cancer Center
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The University of Texas M.D. Anderson Cancer Center, American University of Beirut
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Huntsman Cancer Institute, University of Utah
Co-authored papers 4
University of Navarra
Co-authored papers 4
Co-authored papers 3
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Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Frederick National Laboratory for Cancer Research
Co-authored papers 3
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Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 2
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Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
CNRS UMR9018, Institut Gustave Roussy, Universite Paris-Saclay
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University of Pennsylvania
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Instituto Universitario de Oncologia, Universidad de Oviedo
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New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 2
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
Armed Forces Radiobiology Research Institute
Co-authored papers 2
Winship Cancer Institute, Emory University
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University at Albany
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