Author details

Full Name

David P Toczyski

Affiliation

University of California San Francisco

ORCID

Career Start Year

1991

Papers

H Index

Expertise

CM4AI Collaborator

Nevan J Krogan (CM4AI)

PMID	Paper Title	Journal Title	Published Year
33063175	Redundant targeting of Isr1 by two CDKs in mitotic cells.	Curr Genet	2021
33539788	A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis.	Mol Cell	2021
34382013	Chemical-genetic CRISPR-Cas9 screens in human cells using a pathway-specific library.	STAR Protoc	2021
32579556	The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae.	PLoS Genet	2020
33320706	Fifty years of cycling.	Mol Biol Cell	2020
30420521	Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.	EMBO Rep	2019
31671089	Mck1 kinase is a new player in the DNA damage checkpoint pathway.	PLoS Genet	2019
30850062	A genetic approach to study polyubiquitination in Saccharomyces cerevisiae.	Methods Enzymol	2019
30547882	Genetic analysis reveals functions of atypical polyubiquitin chains.	Elife	2018
30228242	Phosphorylation and Proteasome Recognition of the mRNA-Binding Protein Cth2 Facilitates Yeast Adaptation to Iron Deficiency.	mBio	2018
30377154	The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1.	G3 (Bethesda)	2018
26766115	Isolation of ubiquitinated substrates by tandem affinity purification of E3 ligase-polyubiquitin-binding domain fusions (ligase traps).	Nat Protoc	2016
25381059	Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1.	Mol Cell Proteomics	2015
26431023	Parallel Parkin: Cdc20 Takes a New Partner.	Mol Cell	2015
26161950	Prb1 Protease Activity Is Required for Its Recognition by the F-Box Protein Saf1.	Biochemistry	2015
26091241	DNA Damage Regulates Translation through Î²-TRCP Targeting of CReP.	PLoS Genet	2015
25894965	Ndd1 turnover by SCF(Grr1) is inhibited by the DNA damage checkpoint in Saccharomyces cerevisiae.	PLoS Genet	2015
24389104	Ubiquitin ligase trapping identifies an SCF(Saf1) pathway targeting unprocessed vacuolar/lysosomal proteins.	Mol Cell	2014
24845677	Polymerase stalling during replication, transcription and translation.	Curr Biol	2014
24715726	Hst3 is turned over by a replication stress-responsive SCF(Cdc4) phospho-degron.	Proc Natl Acad Sci U S A	2014
24324011	Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1.	Mol Cell Biol	2014
23973296	Gcn5 and sirtuins regulate acetylation of the ribosomal protein transcription factor Ifh1.	Curr Biol	2013
22426190	Ubiquitin ligases: Taming the APC.	Nat Chem Biol	2012
22844257	F-box protein specificity for g1 cyclins is dictated by subcellular localization.	PLoS Genet	2012
22298423	Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo.	Mol Biol Cell	2012
22405272	Keeping it together in times of stress: checkpoint function at stalled replication forks.	Mol Cell	2012
21307929	Structural biology: a new look for the APC.	Nature	2011
22079111	Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism.	Curr Biol	2011
20126259	CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation.	PLoS Biol	2010
21179023	Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.	Mol Syst Biol	2010
20865002	Damage-induced phosphorylation of Sld3 is important to block late origin firing.	Nature	2010
20962588	Cdc5 blocks in vivo Rad53 activity, but not in situ activity (ISA).	Cell Cycle	2010
20670884	Repair scaffolding reaches new heights at blocked replication forks.	Mol Cell	2010
19285942	Functionally distinct isoforms of Cik1 are differentially regulated by APC/C-mediated proteolysis.	Mol Cell	2009
18471973	Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage.	Mol Cell	2008
19026776	Cdc20, an activator at last.	Mol Cell	2008
17314980	Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.	Nature	2007
17590086	Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase.	PLoS Genet	2007
17828247	A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic-gluconeogenic switch.	Nat Cell Biol	2007
16481473	An architectural map of the anaphase-promoting complex.	Genes Dev	2006
17106263	Taking it off: regulation of H3 K56 acetylation by Hst3 and Hst4.	Cell Cycle	2006
17114580	Precise destruction: an emerging picture of the APC.	Genes Dev	2006
16793400	Methods for studying adaptation to the DNA damage checkpoint in yeast.	Methods Enzymol	2006
16818235	Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4.	Mol Cell	2006
15691649	Damage in transition.	Trends Biochem Sci	2005
15989948	Complicated tails: histone modifications and the DNA damage response.	Cell	2005
15034296	Cycling without the cyclosome: modeling a yeast strain lacking the APC.	Cell Cycle	2004
15589151	DNA breaks promote genomic instability by impeding proper chromosome segregation.	Curr Biol	2004
14634663	Securin and B-cyclin/CDK are the only essential targets of the APC.	Nat Cell Biol	2003
11891124	A unified view of the DNA-damage checkpoint.	Curr Opin Cell Biol	2002

1 - 50 of 57

Nicole Hustedt

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital

Career Start Year 2012

Number of shared co-authors 3

David Gallo

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital

Career Start Year 2010

Number of shared co-authors 2

Laura Pontano Vaites

Harvard Medical School

Career Start Year 2007

Number of shared co-authors 2

Vincent Vanoosthuyse

Ecole Normale Superieure de Lyon, CNRS

Career Start Year 2001

Number of shared co-authors 6

Haico van Attikum

Leiden University Medical Center

Career Start Year 2001

Number of shared co-authors 3

Junjie Chen

The University of Texas MD Anderson Cancer Center

Career Start Year 2000

Number of shared co-authors 0

Rachel Toth

University of Dundee

Career Start Year 1999

Number of shared co-authors 7

Claudia Lukas

Novo Nordisk Foundation Center for Protein Research, University of Copenhagen

Career Start Year 1999

Number of shared co-authors 1

Elah Pick

University of Haifa

Career Start Year 1998

Number of shared co-authors 2

Xiaolan Zhao

Memorial Sloan-Kettering Cancer Center

Career Start Year 1998

Number of shared co-authors 2

Aaron Aslanian

Salk Institute for Biological Studies

Career Start Year 1998

Number of shared co-authors 2

Marcus B Smolka

Weill Institute for Cell and Molecular Biology, Cornell University

Career Start Year 1998

Number of shared co-authors 3

Michael Rape

Howard Hughes Medical Institute, University of California at Berkeley

Career Start Year 1998

Number of shared co-authors 4

Peter H Thorpe

Queen Mary University

Career Start Year 1997

Number of shared co-authors 1

Kenji Shimada

Friedrich Miescher Institute for Biomedical Research

Career Start Year 1997

Number of shared co-authors 0

Simon J Boulton

The Francis Crick Institute

Career Start Year 1996

Number of shared co-authors 1

Kristin Baetz

Ottawa Institute of Systems Biology, University of Ottawa, University of Calgary

Career Start Year 1994

Number of shared co-authors 10

Jennifer L Gerton

Stowers Institute for Medical Research

Career Start Year 1992

Number of shared co-authors 0

Alex Vassilev

National Institute of Child Health & Human Development, National Institutes of Health

Career Start Year 1991

Number of shared co-authors 1

Matthias Peter

Institute of Biochemistry, ETH Zurich

Career Start Year 1989

Number of shared co-authors 11

Peter K Jackson

Stanford University School of Medicine, Center for Clinical Sciences Research

Career Start Year 1989

Number of shared co-authors 5

Stephen P Jackson

Mission Therapeutics Ltd. Glenn Berge Building

Career Start Year 1987

Number of shared co-authors 2

Mike Tyers

Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal

Career Start Year 1986

Number of shared co-authors 10

David Lydall

Institute for Cell and Molecular Biosciences, Newcastle University Medical School

Career Start Year 1986

Number of shared co-authors 7

Yolanda Sanchez

Collegeville

Career Start Year 1985

Number of shared co-authors 1

Susan M Gasser

L'Institut Suisse de Recherche Experimentale sur le Cancer (ISREC) Foundation

Career Start Year 1982

Number of shared co-authors 5

Ashok R Venkitaraman

University of Cambridge, Hutchison Research Centre

Career Start Year 1982

Number of shared co-authors 1

J. Wade Harper

Harvard Medical School

Career Start Year 1981

Number of shared co-authors 6

Rodney Rothstein

Columbia University Vagelos College of Physicians & Surgeons

Career Start Year 1977

Number of shared co-authors 5

Paul Russell

The Scripps Research Institute

Career Start Year 1973

Number of shared co-authors 4

row(s) 1 - 30 of 30

Nevan J Krogan (CM4AI)

University of California San Francisco

Co-authored papers 7

James A Wohlschlegel

David Geffen School of Medicine, University of California Los Angeles

Co-authored papers 7

Ajay A Vashisht

David Geffen School of Medicine, University of California los angeles

Co-authored papers 5

Kevin G Mark

University of California at Berkeley

Co-authored papers 4

Nancy L Maas

University of Pennsylvania

Co-authored papers 4

Jeffrey R Johnson

Gladstone Institutes

Co-authored papers 4

Michael Downey

Ottawa Institute of Systems Biology, University of Ottawa

Co-authored papers 4

Kyle M Miller

The University of Texas at Austin

Co-authored papers 3

Billy W Newton

University of California San Francisco

Co-authored papers 3

Charles A Seller

Cell and Developmental Biology Department University of California San Diego

Co-authored papers 3

Theresa J Berens

University of California san francisco

Co-authored papers 3

Fernando Meza-Gutierrez

University of California san francisco

Co-authored papers 3

Katie M Ulrich

University of California san francisco

Co-authored papers 2

Michael Shales

University of California, USA Quantitative Biosciences Institute (QBI) san francisco

Co-authored papers 2

Shastyn Galaang

University of California san francisco

Co-authored papers 2

Deniz Simsek

Eskisehir Technical University

Co-authored papers 2

Michelle Nguyen

School of Medicine Stanford University

Co-authored papers 1

Jiewei Xu

Quantitative Biosciences Institute (QBI), University of California san francisco

Co-authored papers 1

C David Allis

The Rockefeller University

Co-authored papers 1

Lars M Steinmetz

Stanford University

Co-authored papers 1

Shelley L Berger

Penn Epigenetics Institute, Perelman School of Medicine

Co-authored papers 1

Emma B Alme

University of California San Francisco

Co-authored papers 1

Benjamin Cheng

Co-authored papers 1

Raquel Tamse-Kuehn

Stanford University

Co-authored papers 1

Norman E Davey

The Institute of Cancer Research

Co-authored papers 1

Eul??lia de Nadal

Universitat Pompeu Fabra

Co-authored papers 1

Adam M Deutschbauer

Lawrence Berkeley National Laboratory

Co-authored papers 1

James E Haber

Brandeis University

Co-authored papers 1

Sarah Galicia

Co-authored papers 1

Sigurd Braun

Biomedical Center, Ludwig-Maximilians-Universitat of Munich

Co-authored papers 1

1 - 30

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