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Author Details

J S Emtage
1973
61
40
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
25825497LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.J Biol Chem2015
22544723Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.Proteins2012
23071334Crystal structure of the human PRMT5:MEP50 complex.Proc Natl Acad Sci U S A2012
21365675Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.Proteins2011
21998098The catalase activity of diiron adenine deaminase.Protein Sci2011
21779408Structural and functional profiling of the human histone methyltransferase SMYD3.PLoS One2011
20310066Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.Proteins2010
20687133Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide-binding domain 1.Protein Sci2010
20737437Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.Proteins2010
20943661Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.J Biol Chem2010
20156452Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.J Mol Biol2010
20150177Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.Protein Eng Des Sel2010
19934279SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.Mol Cancer Ther2009
18235434Protein production and purification.Nat Methods2008
18542890High throughput protein production and crystallization at NYSGXRC.Methods Mol Biol2008
18058037Structural genomics of protein phosphatases.J Struct Funct Genomics2007
15528182Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.J Biol Chem2005
16211523New York-Structural GenomiX Research Consortium (NYSGXRC): a large scale center for the protein structure initiative.J Struct Funct Genomics2005
16021622Structural analysis of a set of proteins resulting from a bacterial genomics project.Proteins2005
14685259Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.EMBO J2004
11259407The epithelium-specific ETS protein EHF/ESE-3 is a context-dependent transcriptional repressor downstream of MAPK signaling cascades.J Biol Chem2001
10514907Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity.Arzneimittelforschung1999
9698918Pulmonary biology of anti-interleukin 5 antibodies.Mem Inst Oswaldo Cruz1997
7490135The N-terminal end of the CH2 domain of chimeric human IgG1 anti-HLA-DR is necessary for C1q, Fc gamma RI and Fc gamma RIII binding.Immunology1995
7794042Role of TNF alpha in the induction of antigen induced arthritis in the rabbit and the anti-arthritic effect of species specific TNF alpha neutralising monoclonal antibodies.Ann Rheum Dis1995
7613159Inhibition of pulmonary eosinophilia and hyperreactivity by antibodies to interleukin-5.Int Arch Allergy Immunol1995
7558164Comprehensive pharmacokinetics of a humanized antibody and analysis of residual anti-idiotypic responses.Immunology1995
8113678Differential effect of isotype on efficacy of anti-tumor necrosis factor alpha chimeric antibodies in experimental septic shock.J Exp Med1994
1422059Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli. 1980.Biotechnology1992
1522589Crystal structure of a chimeric Fab' fragment of an antibody binding tumour cells.J Mol Biol1992
2481270A 6-fold difference in the half-life of immunoglobulin mu heavy chain mRNA in cell lines representing two stages of B cell differentiation.Nucleic Acids Res1989
3153139Expression of heterologous genes in E. coli.Microbiol Sci1986
3090401Cloning of cDNA coding for human tissue-type plasminogen activator and its expression in Escherichia coli.Mol Biol Med1986
3920532The synthesis and in vivo assembly of functional antibodies in yeast.Nature1985
3861941DNA makes protein makes money.Nature1985
3839077Molecular cloning and nucleotide sequence of rat lingual lipase cDNA.Nucleic Acids Res1985
6091031Codon usage can affect efficiency of translation of genes in Escherichia coli.Nucleic Acids Res1984
6328446The influence of messenger RNA secondary structure on expression of an immunoglobulin heavy chain in Escherichia coli.Nucleic Acids Res1984
6328437Assembly of functional antibodies from immunoglobulin heavy and light chains synthesised in E. coli.Nucleic Acids Res1984
6304731Synthesis of calf prochymosin (prorennin) in Escherichia coli.Proc Natl Acad Sci U S A1983
6313478Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae.Gene1983
6195046Expression plasmid vectors containing Escherichia coli tryptophan promoter transcriptional units lacking the attenuator.Gene1983
7196502Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes.Nature1981
6246398The construction and characterisation of plasmid vectors suitable for the expression of all DNA phases under the control of the E. coli tryptophan promoter.Mol Gen Genet1980
7010377The production of vaccines by recombinant DNA techniques.Prog Clin Biol Res1980
6159597The amino-terminal sequence of human fibroblast interferon as deduced from reverse transcripts obtained using synthetic oligonucleotide primers.Nucleic Acids Res1980
6159580The complete amino acid sequence of human fibroblast interferon as deduced using synthetic oligodeoxyribonucleotide primers of reverse transcriptase.Nucleic Acids Res1980
6153930Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA.Cell1980
6153123Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli.Nature1980
6254054Nucleotide sequence of influenza virus RNA segment 8 indicates that coding regions for NS1 and NS2 proteins overlap.Proc Natl Acad Sci U S A1980
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Collaborators

Eli Lilly and Co.
Co-authored papers 16
The State University of New Jersey
Co-authored papers 13
New York SGX Research Center for Structural Genomics
Co-authored papers 12
Lilly Research Laboratories
Co-authored papers 10
Argonne National Laboratory
Co-authored papers 10
NYU Langone Hospital - Brooklyn Brooklyn
Co-authored papers 10
Stanford University
Co-authored papers 8
University of California San Francisco
Co-authored papers 7
Albert Einstein College of Medicine
Co-authored papers 6
Co-authored papers 5
Albert Einstein College of Medicine
Co-authored papers 5
Co-authored papers 5
Brookhaven National Laboratory
Co-authored papers 5
Columbia University
Co-authored papers 5
New York University Grossman School of Medicine
Co-authored papers 5
Albert Einstein College of Medicine
Co-authored papers 4
Case Western Reserve University
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Co-authored papers 4
University of California
Co-authored papers 3
Co-authored papers 3
US Department of Energy Joint Genome Institute, Lawrence Berkeley National Laboratory
Co-authored papers 3
Creighton University
Co-authored papers 3
Korea Advanced Institute of Science and Technology (KAIST)
Co-authored papers 3
Co-authored papers 3
The Rockefeller University
Co-authored papers 3
The Rockefeller University
Co-authored papers 3
Stanford University
Co-authored papers 3
Co-authored papers 2
Brookhaven National Laboratory
Co-authored papers 2