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Author Details
Full Name
Hamilton O Smith
Affiliation
J. Craig Venter Institute
ORCID
Career Start Year
1964
Papers
149
H Index
68
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
35063075
Fundamental behaviors emerge from simulations of a living minimal cell.
Cell
2022
32993167
Gross Chromosomal Rearrangements in <i>Kluyveromyces marxianus</i> Revealed by Illumina and Oxford Nanopore Sequencing.
Int J Mol Sci
2020
30657448
Essential metabolism for a minimal cell.
Elife
2019
31850364
Kinetic Modeling of the Genetic Information Processes in a Minimal Cell.
Front Mol Biosci
2019
31262838
Polar Effects of Transposon Insertion into a Minimal Bacterial Genome.
J Bacteriol
2019
29786424
Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells.
ACS Synth Biol
2018
28348033
Minimal Cells-Real and Imagined.
Cold Spring Harb Perspect Biol
2017
27013737
Design and synthesis of a minimal bacterial genome.
Science
2016
27489041
One step engineering of the small-subunit ribosomal RNA using CRISPR/Cas9.
Sci Rep
2016
25603181
Designed surface residue substitutions in [NiFe] hydrogenase that improve electron transfer characteristics.
Int J Mol Sci
2015
26185218
The Sequence of the Human Genome.
Clin Chem
2015
25897682
Designer diatom episomes delivered by bacterial conjugation.
Nat Commun
2015
25654978
Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling.
Genome Res
2015
24603933
Transferring whole genomes from bacteria to yeast spheroplasts using entire bacterial cells to reduce DNA shearing.
Nat Protoc
2014
25101070
Rescue of mutant fitness defects using in vitro reconstituted designer transposons in Mycoplasma mycoides.
Front Microbiol
2014
24934472
A broad survey reveals substitution tolerance of residues ligating FeS clusters in [NiFe] hydrogenase.
BMC Biochem
2014
23542886
Direct transfer of whole genomes from bacteria to yeast.
Nat Methods
2013
24325901
Assembly of eukaryotic algal chromosomes in yeast.
J Biol Eng
2013
23819621
Dual organism design cycle reveals small subunit substitutions that improve [NiFe] hydrogenase hydrogen evolution.
J Biol Eng
2013
22941652
Sequence analysis of a complete 1.66 Mb Prochlorococcus marinus MED4 genome cloned in yeast.
Nucleic Acids Res
2012
23651249
Assembly of large, high G+C bacterial DNA fragments in yeast.
ACS Synth Biol
2012
23651007
Cloning the Acholeplasma laidlawii PG-8A genome in Saccharomyces cerevisiae as a yeast centromeric plasmid.
ACS Synth Biol
2012
21257809
[NiFe] hydrogenase from Alteromonas macleodii with unusual stability in the presence of oxygen and high temperature.
Appl Environ Microbiol
2011
21637846
Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Synechococcus elongatus.
PLoS One
2011
21718346
Genetic analysis of the Alteromonas macleodii [NiFe]-hydrogenase.
FEMS Microbiol Lett
2011
21349975
Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Escherichia coli.
Microbiology (Reading)
2011
21107654
Single-step linker-based combinatorial assembly of promoter and gene cassettes for pathway engineering.
Biotechnol Lett
2011
20211840
Cloning whole bacterial genomes in yeast.
Nucleic Acids Res
2010
20935651
Chemical synthesis of the mouse mitochondrial genome.
Nat Methods
2010
20488990
Creation of a bacterial cell controlled by a chemically synthesized genome.
Science
2010
19363495
Enzymatic assembly of DNA molecules up to several hundred kilobases.
Nat Methods
2009
19953084
A systems biology tour de force for a near-minimal bacterium.
Mol Syst Biol
2009
19841849
The evolution of RecD outside of the RecBCD complex.
J Mol Evol
2009
19633107
Discovery of [NiFe] hydrogenase genes in metagenomic DNA: cloning and heterologous expression in Thiocapsa roseopersicina.
Appl Environ Microbiol
2009
19696314
Creating bacterial strains from genomes that have been cloned and engineered in yeast.
Science
2009
18218864
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.
Science
2008
19073939
One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome.
Proc Natl Acad Sci U S A
2008
17355176
The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific.
PLoS Biol
2007
17600181
Genome transplantation in bacteria: changing one species to another.
Science
2007
16407165
Essential genes of a minimal bacterium.
Proc Natl Acad Sci U S A
2006
16286637
Cell-free cloning using phi29 DNA polymerase.
Proc Natl Acad Sci U S A
2005
15001713
Environmental genome shotgun sequencing of the Sargasso Sea.
Science
2004
14657399
Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides.
Proc Natl Acad Sci U S A
2003
16576752
The independence of our genome assemblies.
Proc Natl Acad Sci U S A
2003
11904395
On the sequencing and assembly of the human genome.
Proc Natl Acad Sci U S A
2002
12368868
Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14.
Nature
2002
12368865
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.
Nature
2002
12368813
Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.
Nat Biotechnol
2002
12364791
The genome sequence of the malaria mosquito Anopheles gambiae.
Science
2002
12040188
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.
Science
2002
1 - 50 of 149
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The J. Craig Venter Institute
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Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers
18
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Case Western Reserve University School of Medicine
Co-authored papers
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Center for Computational Biology, Johns Hopkins University
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13
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13
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Mayo Clinic
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12
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University of Maryland School of Medicine, Institute for Genome Sciences
Co-authored papers
12
Robert J Dodson
Northwestern University Biomedical Informatics Center and Center for Genetic Medicine
Co-authored papers
10
Karen A Ketchum
Yale University School of Medicine
Co-authored papers
9
Karen E Nelson
J. Craig Venter Institute, 9605 Medical Center Drive
Co-authored papers
9
Jonathan A Eisen
McLean Hospital
Co-authored papers
8
Stephen L Hoffman
Inc., 9800 Medical Center Drive
Co-authored papers
8
Malcolm J Gardner
J. Craig Venter Institute
Co-authored papers
8
Jeannine D Gocayne
National Institute of Neurological and Communicative Disorders and Stroke
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7
William C Nelson
Pacific Northwest National Laboratory
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7
Daniel J Carucci
US Military Malaria Vaccine Program, Naval Medical Research Center
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7
Leda M Cummings
Institute for Genome Research
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7
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7
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6
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