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Author Details

Hamilton O Smith
J. Craig Venter Institute
1964
149
68
PMIDPaper TitleJournal TitlePublished Year
35063075Fundamental behaviors emerge from simulations of a living minimal cell.Cell2022
32993167Gross Chromosomal Rearrangements in <i>Kluyveromyces marxianus</i> Revealed by Illumina and Oxford Nanopore Sequencing.Int J Mol Sci2020
30657448Essential metabolism for a minimal cell.Elife2019
31850364Kinetic Modeling of the Genetic Information Processes in a Minimal Cell.Front Mol Biosci2019
31262838Polar Effects of Transposon Insertion into a Minimal Bacterial Genome.J Bacteriol2019
29786424Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells.ACS Synth Biol2018
28348033Minimal Cells-Real and Imagined.Cold Spring Harb Perspect Biol2017
27013737Design and synthesis of a minimal bacterial genome.Science2016
27489041One step engineering of the small-subunit ribosomal RNA using CRISPR/Cas9.Sci Rep2016
25603181Designed surface residue substitutions in [NiFe] hydrogenase that improve electron transfer characteristics.Int J Mol Sci2015
26185218The Sequence of the Human Genome.Clin Chem2015
25897682Designer diatom episomes delivered by bacterial conjugation.Nat Commun2015
25654978Bacterial genome reduction using the progressive clustering of deletions via yeast sexual cycling.Genome Res2015
24603933Transferring whole genomes from bacteria to yeast spheroplasts using entire bacterial cells to reduce DNA shearing.Nat Protoc2014
25101070Rescue of mutant fitness defects using in vitro reconstituted designer transposons in Mycoplasma mycoides.Front Microbiol2014
24934472A broad survey reveals substitution tolerance of residues ligating FeS clusters in [NiFe] hydrogenase.BMC Biochem2014
23542886Direct transfer of whole genomes from bacteria to yeast.Nat Methods2013
24325901Assembly of eukaryotic algal chromosomes in yeast.J Biol Eng2013
23819621Dual organism design cycle reveals small subunit substitutions that improve [NiFe] hydrogenase hydrogen evolution.J Biol Eng2013
22941652Sequence analysis of a complete 1.66 Mb Prochlorococcus marinus MED4 genome cloned in yeast.Nucleic Acids Res2012
23651249Assembly of large, high G+C bacterial DNA fragments in yeast.ACS Synth Biol2012
23651007Cloning the Acholeplasma laidlawii PG-8A genome in Saccharomyces cerevisiae as a yeast centromeric plasmid.ACS Synth Biol2012
21257809[NiFe] hydrogenase from Alteromonas macleodii with unusual stability in the presence of oxygen and high temperature.Appl Environ Microbiol2011
21637846Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Synechococcus elongatus.PLoS One2011
21718346Genetic analysis of the Alteromonas macleodii [NiFe]-hydrogenase.FEMS Microbiol Lett2011
21349975Heterologous expression of Alteromonas macleodii and Thiocapsa roseopersicina [NiFe] hydrogenases in Escherichia coli.Microbiology (Reading)2011
21107654Single-step linker-based combinatorial assembly of promoter and gene cassettes for pathway engineering.Biotechnol Lett2011
20211840Cloning whole bacterial genomes in yeast.Nucleic Acids Res2010
20935651Chemical synthesis of the mouse mitochondrial genome.Nat Methods2010
20488990Creation of a bacterial cell controlled by a chemically synthesized genome.Science2010
19363495Enzymatic assembly of DNA molecules up to several hundred kilobases.Nat Methods2009
19953084A systems biology tour de force for a near-minimal bacterium.Mol Syst Biol2009
19841849The evolution of RecD outside of the RecBCD complex.J Mol Evol2009
19633107Discovery of [NiFe] hydrogenase genes in metagenomic DNA: cloning and heterologous expression in Thiocapsa roseopersicina.Appl Environ Microbiol2009
19696314Creating bacterial strains from genomes that have been cloned and engineered in yeast.Science2009
18218864Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome.Science2008
19073939One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome.Proc Natl Acad Sci U S A2008
17355176The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific.PLoS Biol2007
17600181Genome transplantation in bacteria: changing one species to another.Science2007
16407165Essential genes of a minimal bacterium.Proc Natl Acad Sci U S A2006
16286637Cell-free cloning using phi29 DNA polymerase.Proc Natl Acad Sci U S A2005
15001713Environmental genome shotgun sequencing of the Sargasso Sea.Science2004
14657399Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides.Proc Natl Acad Sci U S A2003
16576752The independence of our genome assemblies.Proc Natl Acad Sci U S A2003
11904395On the sequencing and assembly of the human genome.Proc Natl Acad Sci U S A2002
12368868Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14.Nature2002
12368865Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.Nature2002
12368813Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.Nat Biotechnol2002
12364791The genome sequence of the malaria mosquito Anopheles gambiae.Science2002
12040188A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.Science2002
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Collaborators

The J. Craig Venter Institute
Co-authored papers 55
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 18
Case Western Reserve University School of Medicine
Co-authored papers 18
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 17
Center for Computational Biology, Johns Hopkins University
Co-authored papers 15
The Institute for Genomic Research, 9712 Medical Center Drive
Co-authored papers 13
J. Craig Venter Institute
Co-authored papers 13
Mayo Clinic
Co-authored papers 12
University of Maryland School of Medicine, Institute for Genome Sciences
Co-authored papers 12
Northwestern University Biomedical Informatics Center and Center for Genetic Medicine
Co-authored papers 10
Yale University School of Medicine
Co-authored papers 9
J. Craig Venter Institute, 9605 Medical Center Drive
Co-authored papers 9
McLean Hospital
Co-authored papers 8
Inc., 9800 Medical Center Drive
Co-authored papers 8
J. Craig Venter Institute
Co-authored papers 8
National Institute of Neurological and Communicative Disorders and Stroke
Co-authored papers 7
Pacific Northwest National Laboratory
Co-authored papers 7
US Military Malaria Vaccine Program, Naval Medical Research Center
Co-authored papers 7
Institute for Genome Research
Co-authored papers 7
Co-authored papers 7
The J. Craig Venter Institute.
Co-authored papers 6
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 6
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 6
Oncology R&D
Co-authored papers 5
Illumina Inc.
Co-authored papers 5
University of Central Florida
Co-authored papers 5
Johns Hopkins Bayview Research Campus
Co-authored papers 5
Center for Genomics and Bioinformatics, Indiana University
Co-authored papers 5
Institute of Psychology, Jagiellonian University
Co-authored papers 5
National Cancer Institute
Co-authored papers 5