|
| 36222588 | Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice. | Toxicol Sci | 2023 |
| 37789023 | Characterizing the impact of simvastatin co-treatment of cell specific TCDD-induced gene expression and systemic toxicity. | Sci Rep | 2023 |
| 37602218 | Generative modeling of single-cell gene expression for dose-dependent chemical perturbations. | Patterns (N Y) | 2023 |
| 37352010 | A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data. | Environ Health Perspect | 2023 |
| 37184393 | Cystine/Glutamate Xc<sup>-</sup> Antiporter Induction Compensates for Transsulfuration Pathway Repression by 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) to Ensure Cysteine for Hepatic Glutathione Biosynthesis. | Chem Res Toxicol | 2023 |
| 36914879 | Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver. | Sci Rep | 2023 |
| 35061903 | Benchmarking of a Bayesian single cell RNAseq differential gene expression test for dose-response study designs. | Nucleic Acids Res | 2022 |
| 36422908 | A Physiologically Based Pharmacokinetic (PBPK) Modeling Framework for Mixtures of Dioxin-like Compounds. | Toxics | 2022 |
| 35931118 | Dioxin-elicited decrease in cobalamin redirects propionyl-CoA metabolism to the β-oxidation-like pathway resulting in acrylyl-CoA conjugate buildup. | J Biol Chem | 2022 |
| 35163483 | Genome-Wide ChIPseq Analysis of AhR, COUP-TF, and HNF4 Enrichment in TCDD-Treated Mouse Liver. | Int J Mol Sci | 2022 |
| 32791302 | Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin. | Cell Mol Gastroenterol Hepatol | 2021 |
| 33720361 | Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse Liver. | Toxicol Sci | 2021 |
| 34830313 | Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin (TCDD) Dose-Dependently Shifts the Gut Microbiome Consistent with the Progression of Non-Alcoholic Fatty Liver Disease. | Int J Mol Sci | 2021 |
| 34344994 | Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic β-oxidation. | Sci Rep | 2021 |
| 32387183 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic polyunsaturated fatty acid metabolism and eicosanoid biosynthesis in female Sprague-Dawley rats. | Toxicol Appl Pharmacol | 2020 |
| 31728591 | Gene co-regulation and co-expression in the aryl hydrocarbon receptor-mediated transcriptional regulatory network in the mouse liver. | Arch Toxicol | 2020 |
| 31881176 | A toxicogenomic approach for the risk assessment of the food contaminant acetamide. | Toxicol Appl Pharmacol | 2020 |
| 32908189 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice. | Sci Rep | 2020 |
| 31015483 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice. | Sci Rep | 2019 |
| 31676775 | Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice. | Sci Rep | 2019 |
| 29752288 | Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin-Treated Mice Demonstrates NRF2-Independent PKM2 Induction. | Mol Pharmacol | 2018 |
| 29673856 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice. | Toxicol Appl Pharmacol | 2018 |
| 29501526 | Corrigendum to "Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity" [Toxicol. Appl. Pharmacol. 321 (2017) 1-17]. | Toxicol Appl Pharmacol | 2018 |
| 27913140 | Comparative analysis of TCDD-induced AhR-mediated gene expression in human, mouse and rat primary B cells. | Toxicol Appl Pharmacol | 2017 |
| 28475713 | TCDD influences reservoir of antibiotic resistance genes in murine gut microbiome. | FEMS Microbiol Ecol | 2017 |
| 28213091 | Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity. | Toxicol Appl Pharmacol | 2017 |
| 28238261 | Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. | Chem Res Toxicol | 2017 |
| 28948239 | Beyond the Aryl Hydrocarbon Receptor: Pathway Interactions in the Hepatotoxicity of 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-dioxin and Related Compounds. | Curr Opin Toxicol | 2017 |
| 28725001 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism. | Sci Rep | 2017 |
| 28922406 | Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice. | PLoS One | 2017 |
| 26203683 | Ozone-Induced Type 2 Immunity in Nasal Airways. Development and Lymphoid Cell Dependence in Mice. | Am J Respir Cell Mol Biol | 2016 |
| 26582802 | Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. | Toxicol Sci | 2016 |
| 27613713 | From the Cover: Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis. | Toxicol Sci | 2016 |
| 27562557 | Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis. | Toxicol Sci | 2016 |
| 26921287 | Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism. | Blood | 2016 |
| 25274660 | Development of a computational high-throughput tool for the quantitative examination of dose-dependent histological features. | Toxicol Pathol | 2015 |
| 26377647 | 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice. | Toxicol Sci | 2015 |
| 26377646 | Atrazine-Mediated Disruption of Steroidogenesis in BLTK1 Murine Leydig Cells. | Toxicol Sci | 2015 |
| 26422241 | Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice. | PLoS One | 2015 |
| 25958198 | RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice. | BMC Genomics | 2015 |
| 22977169 | TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice. | Toxicol Sci | 2013 |
| 24096037 | o-p'-DDT-mediated uterotrophy and gene expression in immature C57BL/6 mice and Sprague-Dawley rats. | Toxicol Appl Pharmacol | 2013 |
| 23864506 | Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice. | Toxicol Sci | 2013 |
| 23994337 | Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver. | Toxicol Lett | 2013 |
| 23811191 | PPARα-mediated responses in human adult liver stem cells: In vivo/in vitro and cross-species comparisons. | J Steroid Biochem Mol Biol | 2013 |
| 23418086 | Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes. | Toxicol Sci | 2013 |
| 23591565 | Triazine herbicides and their chlorometabolites alter steroidogenesis in BLTK1 murine Leydig cells. | Toxicol Sci | 2013 |
| 23238561 | Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice. | Toxicol Appl Pharmacol | 2013 |
| 21964420 | Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver. | Toxicol Sci | 2012 |
| 22539624 | Dietary fat is a lipid source in 2,3,7,8-tetrachlorodibenzo-Ï-dioxin (TCDD)-elicited hepatic steatosis in C57BL/6 mice. | Toxicol Sci | 2012 |