|
| 37321988 | Adaptive bias correction for improved subseasonal forecasting. | | 2023 |
| 36764301 | Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects. | Neuron | 2023 |
| 35115730 | Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. | Nat Neurosci | 2022 |
| 36181583 | Single cell metabolism: current and future trends. | Metabolomics | 2022 |
| 35758799 | Self-supervised learning of cell type specificity from immunohistochemical images. | | 2022 |
| 36207580 | A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses. | Commun Biol | 2022 |
| 36543778 | Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. | Nat Commun | 2022 |
| 34465166 | Phenotyping Neurodegeneration in Human iPSCs. | | 2021 |
| 34296279 | Immortalized striatal precursor neurons from Huntington's disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics. | Human Molecular Genetics | 2021 |
| 34253920 | Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. | Nat Genet | 2021 |
| 33311497 | Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. | NPJ Parkinsons Dis | 2020 |
| 31969612 | A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules. | Scientific Reports | 2020 |
| 31696228 | Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice. | Human Molecular Genetics | 2020 |
| 32109367 | Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. | Stem Cell Reports | 2020 |
| 32152337 | APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice. | Scientific Reports | 2020 |
| 30963076 | Shallow Sparsely-Connected Autoencoders for Gene Set Projection. | Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing | 2019 |
| 31744868 | Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease. | Proceedings of the National Academy of Sciences of the United States of America | 2019 |
| 30295334 | Characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident. | Am J Hematol | 2019 |
| 31455666 | Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development. | Blood advances | 2019 |
| 29199020 | The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. | Cell Syst | 2018 |
| 29018056 | Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding. | Mol Cancer Res | 2018 |
| 30257219 | Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data. | Cell Rep | 2018 |
| 30205044 | Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. | Cancer Cell | 2018 |
| 30149217 | Turning omics data into therapeutic insights. | Current Opinion in Pharmacology | 2018 |
| 29765022 | Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease. | Nature Communications | 2018 |
| 29566793 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. | Neuron | 2018 |
| 29344883 | Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data. | Methods in Molecular Biology | 2018 |
| 28131822 | Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. | Cell Syst | 2017 |
| 28726821 | The whole-genome landscape of medulloblastoma subtypes. | Nature | 2017 |
| 28759592 | PCSF: An R-package for network-based interpretation of high-throughput data. | PLoS Computational Biology | 2017 |
| 28931805 | Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements. | Nat Commun | 2017 |
| 29023490 | Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens. | PLoS One | 2017 |
| 28514657 | Huntington's Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits. | Cell Reports | 2017 |
| 29241556 | Hepatic Dysfunction Caused by Consumption of a High-Fat Diet. | Cell Rep | 2017 |
| 28282965 | Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis. | Scientific Reports | 2017 |
| 27479327 | Revealing disease-associated pathways by network integration of untargeted metabolomics. | Nat Methods | 2016 |
| 26748710 | Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements. | Cell Rep | 2016 |
| 27146274 | Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. | Sci Rep | 2016 |
| 27012813 | DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. | Clin Cancer Res | 2016 |
| 27096930 | Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package. | PLoS Comput Biol | 2016 |
| 26864203 | Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. | Proc Natl Acad Sci U S A | 2016 |
| 27315426 | Pathway-based network modeling finds hidden genes in shRNA screen for regulators of acute lymphoblastic leukemia. | Integr Biol (Camb) | 2016 |
| 27354287 | Network Modeling Identifies Patient-specific Pathways in Glioblastoma. | Sci Rep | 2016 |
| 25385494 | Bmi1 promotes erythroid development through regulating ribosome biogenesis. | Stem Cells | 2015 |
| 25414365 | SAMNetWeb: identifying condition-specific networks linking signaling and transcription. | Bioinformatics | 2015 |
| 24297532 | Sharing information to reconstruct patient-specific pathways in heterogeneous diseases. | Pac Symp Biocomput | 2014 |
| 23703590 | The small molecule, genistein, increases hepcidin expression in human hepatocytes. | Hepatology | 2013 |
| 23811269 | Integrated network analyses for functional genomic studies in cancer. | Semin Cancer Biol | 2013 |
| 24095730 | Analysis of in vitro insulin-resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance. | Cell Rep | 2013 |
| 23872847 | Targeting H3K4 trimethylation in Huntington disease. | Proc Natl Acad Sci U S A | 2013 |