Skip to Main Content

Author Details

James DeGregori
University of Colorado Anschutz Medical Campus
1991
161
59
PMIDPaper TitleJournal TitlePublished Year
37492150The paradox of cooperation among selfish cancer cells.Evol Appl2023
37537258Our ancestry dictates clonal architecture and skin cancer susceptibility.Nat Genet2023
37639330Reduced Progenitor Function and Altered Immune Landscape Contribute to Field Cancerization of Lung Adenocarcinoma.Am J Respir Crit Care Med2023
36188489Cancer and aging: A call to action.Aging Cancer2022
35838049Dissecting stepwise mutational impairment of megakaryopoiesis in a model of Down syndrome-associated leukemia.J Clin Invest2022
35726685The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging-related disease.Mol Oncol2022
35494229Resilience integrates concepts in aging research.iScience2022
35394495Dnmt3a-Mutant Hematopoietic Stem Cell Rewire IFNγ Signaling to Gain Clonal Advantage.Blood Cancer Discov2022
35659875Clonal hematopoiesis: Mutation-specific adaptation to environmental change.Cell Stem Cell2022
35781581Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes.Med Oncol2022
36196576Dangerous Liaisons between Tet2 Mutation, Inflammatory Monocytes, and Leukemogenesis.Cancer Discov2022
36259537Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation.Elife2022
33480151Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.Aging Cell2021
33649199Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.Proc Natl Acad Sci U S A2021
33787858Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation.Blood Adv2021
33897809Identifying key questions in the ecology and evolution of cancer.Evol Appl2021
33784238Group phenotypic composition in cancer.Elife2021
33531425Shedding Light on Mutant Clonal Dynamics and Cancer Risk in the Skin.Cancer Discov2021
33857288PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.J Exp Med2021
33914855Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors.J Exp Med2021
34888527Cells with Cancer-associated Mutations Overtake Our Tissues as We Age.Aging Cancer2021
34079113Cancer stem cells in the gut have a bad influence on neighbouring cells.Nature2021
32645167Aging, inflammation, and HSC.Blood2020
31642480Molecular Biology and Evolution of Cancer: From Discovery to Action.Mol Biol Evol2020
32042067Cancer as a disease of old age: changing mutational and microenvironmental landscapes.Br J Cancer2020
32005650Of mice, genes and aging.Haematologica2020
33134891Approaching Cancer Evolution from Different Angles.iScience2020
32946774Cancer Screening, Surrogates of Survival, and the Soma.Cancer Cell2020
32822582Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells.Cell Stem Cell2020
32821282The special issue on cancer and evolution: Lessons learned.Evol Appl2020
32821273The three dimensions of somatic evolution: Integrating the role of genetic damage, life-history traits, and aging in carcinogenesis.Evol Appl2020
32699207A somatic evolutionary model of the dynamics of aneuploid cells during hematopoietic reconstitution.Sci Rep2020
30606720SIX2 Mediates Late-Stage Metastasis via Direct Regulation of <i>SOX2</i> and Induction of a Cancer Stem Cell Program.Cancer Res2019
31439547Studying Cancer Evolution and Therapeutic Responses in Different Organs: The Pros and Cons of a Broad Focus.Cancer Res2019
31352405FERMI: A Novel Method for Sensitive Detection of Rare Mutations in Somatic Tissue.G3 (Bethesda)2019
31321426Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors.J Natl Cancer Inst2019
31311815TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.Blood2019
31443631Somatic maintenance impacts the evolution of mutation rate.BMC Evol Biol2019
31101624Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II.Blood2019
30808730Urea Cycle Sustains Cellular Energetics upon EGFR Inhibition in EGFR-Mutant NSCLC.Mol Cancer Res2019
30980033Elimination of unfit cells in young and ageing skin.Nature2019
31034356A generalized theory of age-dependent carcinogenesis.Elife2019
30940653Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.Clin Cancer Res2019
30848555Decoy fitness peaks, tumor suppression, and aging.Aging Cell2019
30753831Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2019
28947392Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.Exp Hematol2018
29872579Adenoviral vectors transduce alveolar macrophages in lung cancer models.Oncoimmunology2018
30423294Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.Cancer Cell2018
29507657ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer.Oncotarget2018
27663586AZ1366: An Inhibitor of Tankyrase and the Canonical Wnt Pathway that Limits the Persistence of Non-Small Cell Lung Cancer Cells Following EGFR Inhibition.Clin Cancer Res2017
  • 1 - 50 of 161

Recommended Authors

Weill Cornell Medical College.
Career Start Year 2013
Number of shared co-authors 0
Helen Diller Family Comprehensive Cancer Center
Career Start Year 2004
Number of shared co-authors 1
University of California los angeles
Career Start Year 2003
Number of shared co-authors 1
The University of Texas MD Anderson Cancer Center
Career Start Year 2001
Number of shared co-authors 1
Center for Cancer Research, National Cancer Institute
Career Start Year 2000
Number of shared co-authors 0
Roswell Park Comprehensive Cancer Center
Career Start Year 1999
Number of shared co-authors 0
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
The University of Texas MD Anderson Cancer Center
Career Start Year 1997
Number of shared co-authors 0
University of Rochester
Career Start Year 1997
Number of shared co-authors 1
University of California San Francisco
Career Start Year 1993
Number of shared co-authors 0
Department of Pediatrics Stanford University Stanford California USA.
Career Start Year 1993
Number of shared co-authors 0
St Jude Children's Research Hospital
Career Start Year 1991
Number of shared co-authors 1
Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 1991
Number of shared co-authors 1
Broad Institute of Harvard and MIT
Career Start Year 1990
Number of shared co-authors 2
University of Minnesota
Career Start Year 1990
Number of shared co-authors 0
University of California San Francisco
Career Start Year 1989
Number of shared co-authors 0
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 4
St. Jude Children's Research Hospital
Career Start Year 1989
Number of shared co-authors 1
University of Toronto
Career Start Year 1988
Number of shared co-authors 1
Netherlands Cancer Institute
Career Start Year 1987
Number of shared co-authors 0
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Career Start Year 1987
Number of shared co-authors 4
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Career Start Year 1987
Number of shared co-authors 1
USA The Jackson Laboratory Cancer Center
Career Start Year 1982
Number of shared co-authors 0
University of Cambridge, Hutchison Research Centre
Career Start Year 1982
Number of shared co-authors 0
UCSF Helen Diller Family Comprehensive Cancer Center
Career Start Year 1982
Number of shared co-authors 2
Wellcome Sanger Institute
Career Start Year 1980
Number of shared co-authors 2
Johns Hopkins University School of Medicine
Career Start Year 1978
Number of shared co-authors 1
Baylor College of Medicine
Career Start Year 1975
Number of shared co-authors 0
National Cancer Institute
Career Start Year 1945
Number of shared co-authors 2

Collaborators

University of Colorado Anschutz Medical Campus
Co-authored papers 16
University of Colorado Anschutz Medical Campus
Co-authored papers 14
Huntsman Cancer Institute, The University of Utah
Co-authored papers 12
Emory University School of Medicine
Co-authored papers 11
University of Colorado Anschutz Medical Campus
Co-authored papers 11
Harvard Medical School
Co-authored papers 9
University of Colorado Anschutz Medical Campus
Co-authored papers 9
University of Colorado Anschutz Medical Campus
Co-authored papers 8
University of Colorado Division of Hematology
Co-authored papers 7
University of Colorado School of Medicine
Co-authored papers 6
The Broad Institute of MIT and Harvard
Co-authored papers 5
University of Colorado Anschutz Medical Campus
Co-authored papers 5
Zhejiang University Medical Center
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
University of Colorado Anschutz Medical Campus
Co-authored papers 4
University of Colorado Anschutz Medical Campus
Co-authored papers 4
University of Colorado Anschutz Medical Campus
Co-authored papers 3
University of Colorado, Aurora CO.
Co-authored papers 3
Institute of Metabolism & Integrative Biology, Fudan University
Co-authored papers 3
University of Colorado School of Medicine
Co-authored papers 3
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
University of Colorado Anschutz Medical Campus
Co-authored papers 3
Co-authored papers 2
Duke University
Co-authored papers 2
Oregon Health and Science University
Co-authored papers 2
University of Colorado Denver | Anschutz Medical Campus
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
University of Colorado Anschutz Medical Campus
Co-authored papers 2
University of Colorado School of Medicine
Co-authored papers 1