| 35076389 | Structure of the human ATM kinase and mechanism of Nbs1 binding. | Elife | 2022 |
| 34592688 | Insights into homology search from cryo-EM structures of RecA-DNA recombination intermediates. | Curr Opin Genet Dev | 2021 |
| 33686268 | Structure of the FA core ubiquitin ligase closing the ID clamp on DNA. | Nat Struct Mol Biol | 2021 |
| 32269332 | DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex. | Nature | 2020 |
| 33057191 | Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures. | Nature | 2020 |
| 31577956 | A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. | Cell Rep | 2019 |
| 29236692 | Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40. | Nature | 2017 |
| 27006647 | N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis. | J Biomol Tech | 2016 |
| 26328598 | Correction to N-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent. | J Med Chem | 2015 |
| 26491943 | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. | Elife | 2015 |
| 25430771 | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. | Science | 2014 |
| 23636326 | mTOR kinase structure, mechanism and regulation. | Nature | 2013 |
| 23070815 | Structure and conformational change of a replication protein A heterotrimer bound to ssDNA. | Genes Dev | 2012 |
| 21764741 | Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway. | Science | 2011 |
| 20801936 | Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. | Genes Dev | 2010 |
| 19782031 | Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. | Mol Cell | 2009 |
| 18497818 | Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. | Nature | 2008 |
| 19109893 | Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. | Cell | 2008 |
| 17218261 | Ubiquitination regulates PTEN nuclear import and tumor suppression. | Cell | 2007 |
| 17882165 | Recognition of DNA damage by the Rad4 nucleotide excision repair protein. | Nature | 2007 |
| 17434132 | Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases. | Mol Cell | 2007 |
| 17170710 | The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity. | EMBO J | 2007 |
| 15806108 | Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54. | Nat Struct Mol Biol | 2005 |
| 16209941 | Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase. | Mol Cell | 2005 |
| 16275325 | High-level expression and purification of recombinant SCF ubiquitin ligases. | Methods Enzymol | 2005 |
| 16360038 | Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release. | Cell | 2005 |
| 15703751 | The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction. | Nature | 2005 |
| 15027863 | N-(cycloalkylamino)acyl-2-aminothiazole inhibitors of cyclin-dependent kinase 2. N-[5-[[[5-(1,1-dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a highly efficacious and selective antitumor agent. | J Med Chem | 2004 |
| 15242600 | Structural differences in the DNA binding domains of human p53 and its C. elegans ortholog Cep-1. | Structure | 2004 |
| 12820959 | Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase. | Mol Cell | 2003 |
| 12962634 | Crystal structure of a human Mob1 protein: toward understanding Mob-regulated cell cycle pathways. | Structure | 2003 |
| 14534320 | Werner syndrome protein contains three structure-specific DNA binding domains. | J Biol Chem | 2003 |
| 14580353 | The BRCA2-interacting protein DSS1 is vital for DNA repair, recombination, and genome stability in Ustilago maydis. | Mol Cell | 2003 |
| 12686552 | Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding. | J Biol Chem | 2003 |
| 11877378 | Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. | Genes Dev | 2002 |
| 16033158 | Structural biology of ubiquitin-protein ligases. | Harvey Lect | 2002 |
| 12190313 | Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities. | J Med Chem | 2002 |
| 12228710 | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. | Science | 2002 |
| 12467573 | Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography. | Structure | 2002 |
| 11961546 | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. | Nature | 2002 |
| 12004076 | Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling. | Science | 2002 |
| 12121644 | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate. | Structure | 2002 |
| 11029468 | Kinetic basis for activation of CDK2/cyclin A by phosphorylation. | J Biol Chem | 2001 |
| 11226270 | Role of the F-box protein Skp2 in lymphomagenesis. | Proc Natl Acad Sci U S A | 2001 |
| 11427894 | Structure of the histone deacetylase SIRT2. | Nat Struct Biol | 2001 |
| 11156408 | Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor. | Cancer Res | 2000 |
| 10860994 | Identification and characterization of a p53 homologue in Drosophila melanogaster. | Proc Natl Acad Sci U S A | 2000 |
| 10878807 | Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. | Nat Cell Biol | 2000 |
| 10966114 | Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. | Cell | 2000 |
| 11099048 | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. | Nature | 2000 |