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Author Details

Paul Taylor
Hospital for Sick Children
1999
48
24
PMIDPaper TitleJournal TitlePublished Year
36214668Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non-Small Cell Lung Cancer.Mol Cancer Res2023
35595168Proteomic Characterization of a Candidate Polygenic Driver of Metabolism in Non-small Cell Lung Cancer.J Mol Biol2022
35383171Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes.Nat Commun2022
32903271Cancer proteome and metabolite changes linked to SHMT2.PLoS One2020
30297534Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma.Cancer Res2018
29986722"It's better to have three brains working instead of one": a qualitative study of building therapeutic alliance with family members of critically ill patients.BMC Health Serv Res2018
27750381Molecular heterogeneity of non-small cell lung carcinoma patient-derived xenografts closely reflect their primary tumors.Int J Cancer2017
28176486Integrated analysis of proteome, phosphotyrosine-proteome, tyrosine-kinome, and tyrosine-phosphatome in acute myeloid leukemia.Proteomics2017
28673317The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis.J Hematol Oncol2017
27880036Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS.Proteomics2017
26825710The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice.Blood2016
25403733Comprehensive identification of phosphorylation sites on the Numb endocytic adaptor protein.Proteomics2015
26378716Tracking the Dynamic Relationship between Cellular Systems and Extracellular Subproteomes in Pseudomonas aeruginosa Biofilms.J Proteome Res2015
26237434Distinct Regulation of Transmitter Release at the Drosophila NMJ by Different Isoforms of nemy.PLoS One2015
25721092Comprehensive proteome analysis of fresh frozen and optimal cutting temperature (OCT) embedded primary non-small cell lung carcinoma by LC-MS/MS.Methods2015
25784717CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.Mol Cancer Res2015
25587033Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.Mol Cell Proteomics2015
25311528Differential regulation of FGFR3 by PTPN1 and PTPN2.Proteomics2015
25330774The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation.Proteomics2015
24453208Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches.Proteomics2014
25429762Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact.Nat Commun2014
25326145Purification of protein C from canine plasma.BMC Vet Res2014
24797263Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.Mol Cell Proteomics2014
24532839A temporal examination of the planktonic and biofilm proteome of whole cell Pseudomonas aeruginosa PAO1 using quantitative mass spectrometry.Mol Cell Proteomics2014
23211419Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.Mol Cell Proteomics2013
23825523Odin (ANKS1A) modulates EGF receptor recycling and stability.PLoS One2013
23701117A phosphoproteomics approach to identify candidate kinase inhibitor pathway targets in lymphoma-like primary cell lines.Curr Drug Discov Technol2013
22653920Proteomic profiling of the planarian Schmidtea mediterranea and its mucous reveals similarities with human secretions and those predicted for parasitic flatworms.Mol Cell Proteomics2012
22554165Selected Reaction Monitoring (SRM) Analysis of Epidermal Growth Factor Receptor (EGFR) in Formalin Fixed Tumor Tissue.Clin Proteomics2012
20815376Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.J Proteome Res2011
21884940Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome".Cell2011
21609022Quantitative phospho-proteomic profiling of hepatocyte growth factor (HGF)-MET signaling in colorectal cancer.J Proteome Res2011
20368691Long C terminal splice variant CaV2.2 identified in presynaptic membrane by mass spectrometric analysis.Channels (Austin)2010
20651058System-level analysis of neuroblastoma tumor-initiating cells implicates AURKB as a novel drug target for neuroblastoma.Clin Cancer Res2010
20205385Measurement of protein phosphorylation stoichiometry by selected reaction monitoring mass spectrometry.J Proteome Res2010
19156871Distinct properties of murine alpha 5 gamma-aminobutyric acid type a receptors revealed by biochemical fractionation and mass spectroscopy.J Neurosci Res2009
19901323Multiple myeloma phosphotyrosine proteomic profile associated with FGFR3 expression, ligand activation, and drug inhibition.Proc Natl Acad Sci U S A2009
19531499Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.Mol Cell Proteomics2009
19178303Automated 2D peptide separation on a 1D nano-LC-MS system.J Proteome Res2009
18271526Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.J Proteome Res2008
19064935nemy encodes a cytochrome b561 that is required for Drosophila learning and memory.Proc Natl Acad Sci U S A2008
17353931Large-scale mapping of human protein-protein interactions by mass spectrometry.Mol Syst Biol2007
16889898Emerging applications for phospho-proteomics in cancer molecular therapeutics.Biochim Biophys Acta2006
15324660Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.Curr Biol2004
11805837Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.Nature2002
11238945Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.Mol Cell Biol2001
10848605Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors.Mol Cell Biol2000
10917634Synaptic targeting and regulation of GABA(A) receptors.Biochem Soc Trans1999
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Collaborators

Hospital for Sick Children, University of Toronto
Co-authored papers 40
Hospital for Sick Children
Co-authored papers 22
University Health Network, University of Toronto
Co-authored papers 13
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 9
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 8
Margaret Cancer Center
Co-authored papers 6
The Princess Margaret Cancer Centre/University of Toronto
Co-authored papers 6
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 5
National Cancer Center Exploratory Oncology Research & Clinical Trial Center
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Rosalind and Morris Goodman Cancer Institute, McGill University
Co-authored papers 5
Hospital for Sick Children
Co-authored papers 4
Nanjing Agricultural University
Co-authored papers 4
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Yamagata Prefectural Central Hospital
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
University of Toronto
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Sheffield Institute of Translational Neuroscience, University of Sheffield
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Toronto General Hospital
Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
University of Toronto
Co-authored papers 2